These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 2167153)

  • 1. Role of P450IIE1 in the metabolism of 3-hydroxypyridine, a constituent of tobacco smoke: redox cycling and DNA strand scission by the metabolite 2,5-dihydroxypyridine.
    Kim SG; Novak RF
    Cancer Res; 1990 Sep; 50(17):5333-9. PubMed ID: 2167153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases.
    Kim SG; Philpot RM; Novak RF
    J Pharmacol Exp Ther; 1991 Oct; 259(1):470-7. PubMed ID: 1920133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine.
    Kaul KL; Novak RF
    J Pharmacol Exp Ther; 1987 Oct; 243(1):384-90. PubMed ID: 3668864
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidation of 1,1,1,2-tetrafluoroethane in rat liver microsomes is catalyzed primarily by cytochrome P-450IIE1.
    Olson MJ; Kim SG; Reidy CA; Johnson JT; Novak RF
    Drug Metab Dispos; 1991; 19(2):298-303. PubMed ID: 1676626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N,N',N''-triethylenethiophosphoramide (thio-TEPA) oxygenation by constitutive hepatic P450 enzymes and modulation of drug metabolism and clearance in vivo by P450-inducing agents.
    Ng SF; Waxman DJ
    Cancer Res; 1991 May; 51(9):2340-5. PubMed ID: 1707751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450.
    Kokkinakis DM; Koop DR; Scarpelli DG; Coon MJ; Hollenberg PF
    Cancer Res; 1985 Feb; 45(2):619-24. PubMed ID: 3967237
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyridine induction of cytochrome P-450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation.
    Kim SG; Williams DE; Schuetz EG; Guzelian PS; Novak RF
    J Pharmacol Exp Ther; 1988 Sep; 246(3):1175-82. PubMed ID: 3418515
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G; Longo V; Mazzaccaro A; Gervasi PG
    Chem Res Toxicol; 1996; 9(5):882-90. PubMed ID: 8828925
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxidation of tolualdehydes to toluic acids catalyzed by cytochrome P450-dependent aldehyde oxygenase in the mouse liver.
    Watanabe K; Matsunaga T; Yamamoto I; Yashimura H
    Drug Metab Dispos; 1995 Feb; 23(2):261-5. PubMed ID: 7736922
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
    Ng SF; Waxman DJ
    Cancer Res; 1990 Feb; 50(3):464-71. PubMed ID: 2105156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The mechanism of stimulation of NADPH oxidation during the mechanism-based inactivation of cytochrome P450 2B1 by N-methylcarbazole: redox cycling and DNA scission.
    Shen T; Hollenberg PF
    Chem Res Toxicol; 1994; 7(2):231-8. PubMed ID: 8199313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of halothane oxidation by hepatic microsomes and purified cytochromes P-450 using a gas chromatographic mass spectrometric assay.
    Gruenke LD; Konopka K; Koop DR; Waskell LA
    J Pharmacol Exp Ther; 1988 Aug; 246(2):454-9. PubMed ID: 3404442
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
    Ferrara R; Tolando R; King LJ; Manno M
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytochrome P450IIE1 metabolism of pyridines: evidence for production of a reactive intermediate which exhibits redox-cycling activity and causes DNA damage.
    Kim SG; Novak RF
    Adv Exp Med Biol; 1991; 283():753-8. PubMed ID: 1648871
    [No Abstract]   [Full Text] [Related]  

  • 16. Bioreduction of idarubicin and formation of ROS responsible for DNA cleavage by NADPH-cytochrome P450 reductase and its potential role in the antitumor effect.
    Celik H; Arinç E
    J Pharm Pharm Sci; 2008; 11(4):68-82. PubMed ID: 19183515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation.
    Clarke L; Waxman DJ
    Cancer Res; 1989 May; 49(9):2344-50. PubMed ID: 2706622
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein.
    Chaurasia CS; Alterman MA; Lu P; Hanzlik RP
    Arch Biochem Biophys; 1995 Feb; 317(1):161-9. PubMed ID: 7872779
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
    Cribb AE; Spielberg SP; Griffin GP
    Drug Metab Dispos; 1995 Mar; 23(3):406-14. PubMed ID: 7628308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
    Dekant W; Assmann M; Urban G
    Toxicol Appl Pharmacol; 1995 Dec; 135(2):200-7. PubMed ID: 8545828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.