271 related articles for article (PubMed ID: 21673986)
1. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
Wang Z; Banerjee S; Ahmad A; Li Y; Azmi AS; Gunn JR; Kong D; Bao B; Ali S; Gao J; Mohammad RM; Miele L; Korc M; Sarkar FH
PLoS One; 2011; 6(6):e20537. PubMed ID: 21673986
[TBL] [Abstract][Full Text] [Related]
2. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Wang Z; Ali S; Banerjee S; Bao B; Li Y; Azmi AS; Korc M; Sarkar FH
J Cell Physiol; 2013 Mar; 228(3):556-562. PubMed ID: 22806240
[TBL] [Abstract][Full Text] [Related]
3. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis.
Chang Z; Ju H; Ling J; Zhuang Z; Li Z; Wang H; Fleming JB; Freeman JW; Yu D; Huang P; Chiao PJ
PLoS One; 2014; 9(7):e101452. PubMed ID: 25029561
[TBL] [Abstract][Full Text] [Related]
4. Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways.
Wang Z; Li Y; Banerjee S; Kong D; Ahmad A; Nogueira V; Hay N; Sarkar FH
J Cell Biochem; 2010 Mar; 109(4):726-36. PubMed ID: 20052673
[TBL] [Abstract][Full Text] [Related]
5. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Bardeesy N; Aguirre AJ; Chu GC; Cheng KH; Lopez LV; Hezel AF; Feng B; Brennan C; Weissleder R; Mahmood U; Hanahan D; Redston MS; Chin L; Depinho RA
Proc Natl Acad Sci U S A; 2006 Apr; 103(15):5947-52. PubMed ID: 16585505
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer.
Ali S; Banerjee S; Logna F; Bao B; Philip PA; Korc M; Sarkar FH
J Cell Physiol; 2012 Oct; 227(10):3373-80. PubMed ID: 22213426
[TBL] [Abstract][Full Text] [Related]
7. Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis.
Cano CE; Hamidi T; Garcia MN; Grasso D; Loncle C; Garcia S; Calvo E; Lomberk G; Dusetti N; Bartholin L; Urrutia R; Iovanna JL
Gut; 2014 Jun; 63(6):984-95. PubMed ID: 24026351
[TBL] [Abstract][Full Text] [Related]
8. The NOTCH ligand JAGGED2 promotes pancreatic cancer metastasis independent of NOTCH signaling activation.
Hu Y; Su H; Li X; Guo G; Cheng L; Qin R; Qing G; Liu H
Mol Cancer Ther; 2015 Jan; 14(1):289-97. PubMed ID: 25351917
[TBL] [Abstract][Full Text] [Related]
9. Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Chalabi-Dchar M; Cassant-Sourdy S; Duluc C; Fanjul M; Lulka H; Samain R; Roche C; Breibach F; Delisle MB; Poupot M; Dufresne M; Shimaoka T; Yonehara S; Mathonnet M; Pyronnet S; Bousquet C
Gastroenterology; 2015 Jun; 148(7):1452-65. PubMed ID: 25683115
[TBL] [Abstract][Full Text] [Related]
10. The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling.
Maity G; Haque I; Ghosh A; Dhar G; Gupta V; Sarkar S; Azeem I; McGregor D; Choudhary A; Campbell DR; Kambhampati S; Banerjee SK; Banerjee S
J Biol Chem; 2018 Mar; 293(12):4334-4349. PubMed ID: 29414775
[TBL] [Abstract][Full Text] [Related]
11. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
Ling J; Kang Y; Zhao R; Xia Q; Lee DF; Chang Z; Li J; Peng B; Fleming JB; Wang H; Liu J; Lemischka IR; Hung MC; Chiao PJ
Cancer Cell; 2012 Jan; 21(1):105-20. PubMed ID: 22264792
[TBL] [Abstract][Full Text] [Related]
12. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.
Wang Z; Li Y; Kong D; Banerjee S; Ahmad A; Azmi AS; Ali S; Abbruzzese JL; Gallick GE; Sarkar FH
Cancer Res; 2009 Mar; 69(6):2400-7. PubMed ID: 19276344
[TBL] [Abstract][Full Text] [Related]
13. Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway.
Ogawa K; Lin Q; Li L; Bai X; Chen X; Chen H; Kong R; Wang Y; Zhu H; He F; Xu Q; Liu L; Li M; Zhang S; Nagaoka K; Carlson R; Safran H; Charpentier K; Sun B; Wands J; Dong X
J Hematol Oncol; 2019 Dec; 12(1):144. PubMed ID: 31888763
[TBL] [Abstract][Full Text] [Related]
14. Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1.
Botta GP; Reginato MJ; Reichert M; Rustgi AK; Lelkes PI
Mol Cancer Res; 2012 Feb; 10(2):183-96. PubMed ID: 22160930
[TBL] [Abstract][Full Text] [Related]
15. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Bardeesy N; Cheng KH; Berger JH; Chu GC; Pahler J; Olson P; Hezel AF; Horner J; Lauwers GY; Hanahan D; DePinho RA
Genes Dev; 2006 Nov; 20(22):3130-46. PubMed ID: 17114584
[TBL] [Abstract][Full Text] [Related]
16. p53 and p16
Azzopardi S; Pang S; Klimstra DS; Du YN
Neoplasia; 2016 Oct; 18(10):610-617. PubMed ID: 27664376
[TBL] [Abstract][Full Text] [Related]
17. Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
Maniati E; Bossard M; Cook N; Candido JB; Emami-Shahri N; Nedospasov SA; Balkwill FR; Tuveson DA; Hagemann T
J Clin Invest; 2011 Dec; 121(12):4685-99. PubMed ID: 22056382
[TBL] [Abstract][Full Text] [Related]
18. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
Aguirre AJ; Bardeesy N; Sinha M; Lopez L; Tuveson DA; Horner J; Redston MS; DePinho RA
Genes Dev; 2003 Dec; 17(24):3112-26. PubMed ID: 14681207
[TBL] [Abstract][Full Text] [Related]
19. The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways.
Vasseur R; Skrypek N; Duchêne B; Renaud F; Martínez-Maqueda D; Vincent A; Porchet N; Van Seuningen I; Jonckheere N
Biochim Biophys Acta; 2015 Dec; 1849(12):1375-84. PubMed ID: 26477488
[TBL] [Abstract][Full Text] [Related]
20. Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.
Lashinger LM; Harrison LM; Rasmussen AJ; Logsdon CD; Fischer SM; McArthur MJ; Hursting SD
Cancer Prev Res (Phila); 2013 Oct; 6(10):1046-55. PubMed ID: 23980075
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
