These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
79 related articles for article (PubMed ID: 21676615)
1. Efficient synthesis of 3-O-thia-cPA and preliminary analysis of its biological activity toward autotaxin. Tanaka R; Kato M; Suzuki T; Nakazaki A; Nozaki E; Gotoh M; Murakami-Murofushi K; Kobayashi S Bioorg Med Chem Lett; 2011 Jul; 21(14):4180-2. PubMed ID: 21676615 [TBL] [Abstract][Full Text] [Related]
2. Synthesis of enantiopure 2-carba-cyclic phosphatidic acid and effects of its chirality on biological functions. Nozaki E; Gotoh M; Hotta H; Hanazawa S; Kobayashi S; Murakami-Murofushi K Biochim Biophys Acta; 2011 Apr; 1811(4):271-7. PubMed ID: 21277386 [TBL] [Abstract][Full Text] [Related]
3. Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Gupte R; Siddam A; Lu Y; Li W; Fujiwara Y; Panupinthu N; Pham TC; Baker DL; Parrill AL; Gotoh M; Murakami-Murofushi K; Kobayashi S; Mills GB; Tigyi G; Miller DD Bioorg Med Chem Lett; 2010 Dec; 20(24):7525-8. PubMed ID: 21051230 [TBL] [Abstract][Full Text] [Related]
4. Development of an activity-based probe for autotaxin. Cavalli S; Houben AJ; Albers HM; van Tilburg EW; de Ru A; Aoki J; van Veelen P; Moolenaar WH; Ovaa H Chembiochem; 2010 Nov; 11(16):2311-7. PubMed ID: 20941725 [TBL] [Abstract][Full Text] [Related]
5. Discovery and optimization of boronic acid based inhibitors of autotaxin. Albers HM; van Meeteren LA; Egan DA; van Tilburg EW; Moolenaar WH; Ovaa H J Med Chem; 2010 Jul; 53(13):4958-67. PubMed ID: 20536182 [TBL] [Abstract][Full Text] [Related]
7. Autotaxin: a protein with two faces. Tania M; Khan MA; Zhang H; Li J; Song Y Biochem Biophys Res Commun; 2010 Oct; 401(4):493-7. PubMed ID: 20888793 [TBL] [Abstract][Full Text] [Related]
8. Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. North EJ; Howard AL; Wanjala IW; Pham TC; Baker DL; Parrill AL J Med Chem; 2010 Apr; 53(8):3095-105. PubMed ID: 20349977 [TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors. Cui P; Tomsig JL; McCalmont WF; Lee S; Becker CJ; Lynch KR; Macdonald TL Bioorg Med Chem Lett; 2007 Mar; 17(6):1634-40. PubMed ID: 17257836 [TBL] [Abstract][Full Text] [Related]
10. Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. Gupte R; Patil R; Liu J; Wang Y; Lee SC; Fujiwara Y; Fells J; Bolen AL; Emmons-Thompson K; Yates CR; Siddam A; Panupinthu N; Pham TC; Baker DL; Parrill AL; Mills GB; Tigyi G; Miller DD ChemMedChem; 2011 May; 6(5):922-35. PubMed ID: 21465666 [TBL] [Abstract][Full Text] [Related]
11. Cyclic phosphatidic acid is produced by autotaxin in blood. Tsuda S; Okudaira S; Moriya-Ito K; Shimamoto C; Tanaka M; Aoki J; Arai H; Murakami-Murofushi K; Kobayashi T J Biol Chem; 2006 Sep; 281(36):26081-8. PubMed ID: 16837466 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX). East JE; Kennedy AJ; Tomsig JL; De Leon AR; Lynch KR; Macdonald TL Bioorg Med Chem Lett; 2010 Dec; 20(23):7132-6. PubMed ID: 20951039 [TBL] [Abstract][Full Text] [Related]
13. S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool. Ferry G; Moulharat N; Pradère JP; Desos P; Try A; Genton A; Giganti A; Beucher-Gaudin M; Lonchampt M; Bertrand M; Saulnier-Blache JS; Tucker GC; Cordi A; Boutin JA J Pharmacol Exp Ther; 2008 Dec; 327(3):809-19. PubMed ID: 18755937 [TBL] [Abstract][Full Text] [Related]
15. Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. Baker DL; Fujiwara Y; Pigg KR; Tsukahara R; Kobayashi S; Murofushi H; Uchiyama A; Murakami-Murofushi K; Koh E; Bandle RW; Byun HS; Bittman R; Fan D; Murph M; Mills GB; Tigyi G J Biol Chem; 2006 Aug; 281(32):22786-93. PubMed ID: 16782709 [TBL] [Abstract][Full Text] [Related]
16. Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal. Ferry G; Giganti A; Cogé F; Bertaux F; Thiam K; Boutin JA FEBS Lett; 2007 Jul; 581(18):3572-8. PubMed ID: 17628547 [TBL] [Abstract][Full Text] [Related]
17. Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood. Endo T; Kano K; Motoki R; Hama K; Okudaira S; Ishida M; Ogiso H; Tanaka M; Matsuki N; Taguchi R; Kanai M; Shibasaki M; Arai H; Aoki J J Biochem; 2009 Aug; 146(2):283-93. PubMed ID: 19416959 [TBL] [Abstract][Full Text] [Related]
18. Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid. Altman MK; Gopal V; Jia W; Yu S; Hall H; Mills GB; McGinnis AC; Bartlett MG; Jiang G; Madan D; Prestwich GD; Xu Y; Davies MA; Murph MM Mol Cancer; 2010 Jun; 9():140. PubMed ID: 20529378 [TBL] [Abstract][Full Text] [Related]