BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 21676867)

  • 1. Monoubiquitination of H2AX protein regulates DNA damage response signaling.
    Pan MR; Peng G; Hung WC; Lin SY
    J Biol Chem; 2011 Aug; 286(32):28599-607. PubMed ID: 21676867
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.
    Ginjala V; Nacerddine K; Kulkarni A; Oza J; Hill SJ; Yao M; Citterio E; van Lohuizen M; Ganesan S
    Mol Cell Biol; 2011 May; 31(10):1972-82. PubMed ID: 21383063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA damage signaling in response to double-strand breaks during mitosis.
    Giunta S; Belotserkovskaya R; Jackson SP
    J Cell Biol; 2010 Jul; 190(2):197-207. PubMed ID: 20660628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MDC1 is a mediator of the mammalian DNA damage checkpoint.
    Stewart GS; Wang B; Bignell CR; Taylor AM; Elledge SJ
    Nature; 2003 Feb; 421(6926):961-6. PubMed ID: 12607005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH; Lin L; Zhang X; Nguyen TA; Darlington Y; Waldman AS; Lu X; Donehower LA
    J Biol Chem; 2010 Apr; 285(17):12935-47. PubMed ID: 20118229
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.
    Neumayer G; Helfricht A; Shim SY; Le HT; Lundin C; Belzil C; Chansard M; Yu Y; Lees-Miller SP; Gruss OJ; van Attikum H; Helleday T; Nguyen MD
    J Biol Chem; 2012 Dec; 287(50):42206-22. PubMed ID: 23045526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair.
    Ismail IH; Andrin C; McDonald D; Hendzel MJ
    J Cell Biol; 2010 Oct; 191(1):45-60. PubMed ID: 20921134
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK.
    Meyer B; Voss KO; Tobias F; Jakob B; Durante M; Taucher-Scholz G
    Nucleic Acids Res; 2013 Jul; 41(12):6109-18. PubMed ID: 23620287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.
    Savic V; Yin B; Maas NL; Bredemeyer AL; Carpenter AC; Helmink BA; Yang-Iott KS; Sleckman BP; Bassing CH
    Mol Cell; 2009 May; 34(3):298-310. PubMed ID: 19450528
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells.
    Toller IM; Neelsen KJ; Steger M; Hartung ML; Hottiger MO; Stucki M; Kalali B; Gerhard M; Sartori AA; Lopes M; Müller A
    Proc Natl Acad Sci U S A; 2011 Sep; 108(36):14944-9. PubMed ID: 21896770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
    Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
    EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nucleolin participates in DNA double-strand break-induced damage response through MDC1-dependent pathway.
    Kobayashi J; Fujimoto H; Sato J; Hayashi I; Burma S; Matsuura S; Chen DJ; Komatsu K
    PLoS One; 2012; 7(11):e49245. PubMed ID: 23145133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.
    Marteijn JA; Bekker-Jensen S; Mailand N; Lans H; Schwertman P; Gourdin AM; Dantuma NP; Lukas J; Vermeulen W
    J Cell Biol; 2009 Sep; 186(6):835-47. PubMed ID: 19797077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.
    Moon SH; Nguyen TA; Darlington Y; Lu X; Donehower LA
    Cell Cycle; 2010 Jun; 9(11):2092-6. PubMed ID: 20495376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.
    Pfeiffer A; Luijsterburg MS; Acs K; Wiegant WW; Helfricht A; Herzog LK; Minoia M; Böttcher C; Salomons FA; van Attikum H; Dantuma NP
    EMBO J; 2017 Apr; 36(8):1066-1083. PubMed ID: 28275011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
    Noon AT; Shibata A; Rief N; Löbrich M; Stewart GS; Jeggo PA; Goodarzi AA
    Nat Cell Biol; 2010 Feb; 12(2):177-84. PubMed ID: 20081839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.
    Lee KY; Im JS; Shibata E; Dutta A
    Mol Cell; 2017 Oct; 68(1):61-75.e5. PubMed ID: 28943310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
    An J; Huang YC; Xu QZ; Zhou LJ; Shang ZF; Huang B; Wang Y; Liu XD; Wu DC; Zhou PK
    BMC Mol Biol; 2010 Mar; 11():18. PubMed ID: 20205745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.
    Kobayashi J; Tauchi H; Chen B; Burma S; Tashiro S; Matsuura S; Tanimoto K; Chen DJ; Komatsu K
    Biochem Biophys Res Commun; 2009 Mar; 380(4):752-7. PubMed ID: 19338747
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.