BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

993 related articles for article (PubMed ID: 21677139)

  • 1. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.
    Clayton A; Al-Taei S; Webber J; Mason MD; Tabi Z
    J Immunol; 2011 Jul; 187(2):676-83. PubMed ID: 21677139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2.
    Clayton A; Mitchell JP; Court J; Mason MD; Tabi Z
    Cancer Res; 2007 Aug; 67(15):7458-66. PubMed ID: 17671216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.
    Regateiro FS; Howie D; Nolan KF; Agorogiannis EI; Greaves DR; Cobbold SP; Waldmann H
    Eur J Immunol; 2011 Oct; 41(10):2955-65. PubMed ID: 21770045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.
    Schuler PJ; Saze Z; Hong CS; Muller L; Gillespie DG; Cheng D; Harasymczuk M; Mandapathil M; Lang S; Jackson EK; Whiteside TL
    Clin Exp Immunol; 2014 Aug; 177(2):531-43. PubMed ID: 24749746
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity.
    Bastid J; Regairaz A; Bonnefoy N; Déjou C; Giustiniani J; Laheurte C; Cochaud S; Laprevotte E; Funck-Brentano E; Hemon P; Gros L; Bec N; Larroque C; Alberici G; Bensussan A; Eliaou JF
    Cancer Immunol Res; 2015 Mar; 3(3):254-65. PubMed ID: 25403716
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation.
    Morandi F; Horenstein AL; Chillemi A; Quarona V; Chiesa S; Imperatori A; Zanellato S; Mortara L; Gattorno M; Pistoia V; Malavasi F
    J Immunol; 2015 Aug; 195(3):965-72. PubMed ID: 26091716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation and Function of Non-cell-bound CD73 in Inflammation.
    Schneider E; Rissiek A; Winzer R; Puig B; Rissiek B; Haag F; Mittrücker HW; Magnus T; Tolosa E
    Front Immunol; 2019; 10():1729. PubMed ID: 31404305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice.
    Bao R; Shui X; Hou J; Li J; Deng X; Zhu X; Yang T
    Int J Mol Med; 2016 Sep; 38(3):969-75. PubMed ID: 27430240
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methotrexate up-regulates ecto-5'-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment.
    Figueiró F; de Oliveira CP; Bergamin LS; Rockenbach L; Mendes FB; Jandrey EH; Moritz CE; Pettenuzzo LF; Sévigny J; Guterres SS; Pohlmann AR; Battastini AM
    Purinergic Signal; 2016 Jun; 12(2):303-12. PubMed ID: 26910734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells.
    Kerkelä E; Laitinen A; Räbinä J; Valkonen S; Takatalo M; Larjo A; Veijola J; Lampinen M; Siljander P; Lehenkari P; Alfthan K; Laitinen S
    Stem Cells; 2016 Mar; 34(3):781-90. PubMed ID: 26731338
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CD73 expression on extracellular vesicles derived from CD4+ CD25+ Foxp3+ T cells contributes to their regulatory function.
    Smyth LA; Ratnasothy K; Tsang JY; Boardman D; Warley A; Lechler R; Lombardi G
    Eur J Immunol; 2013 Sep; 43(9):2430-40. PubMed ID: 23749427
    [TBL] [Abstract][Full Text] [Related]  

  • 12. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine.
    Kobie JJ; Shah PR; Yang L; Rebhahn JA; Fowell DJ; Mosmann TR
    J Immunol; 2006 Nov; 177(10):6780-6. PubMed ID: 17082591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High expression of CD39/ENTPD1 in malignant epithelial cells of human rectal adenocarcinoma.
    Zhang B; Cheng B; Li FS; Ding JH; Feng YY; Zhuo GZ; Wei HF; Zhao K
    Tumour Biol; 2015 Dec; 36(12):9411-9. PubMed ID: 26113408
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extracellular ATP inhibits IL-1-induced MMP-1 expression through the action of CD39/nucleotidase triphosphate dephosphorylase-1 on human gingival fibroblasts.
    Nemoto E; Gotoh K; Tsuchiya M; Sakisaka Y; Shimauchi H
    Int Immunopharmacol; 2013 Nov; 17(3):513-8. PubMed ID: 23941770
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
    Deaglio S; Dwyer KM; Gao W; Friedman D; Usheva A; Erat A; Chen JF; Enjyoji K; Linden J; Oukka M; Kuchroo VK; Strom TB; Robson SC
    J Exp Med; 2007 Jun; 204(6):1257-65. PubMed ID: 17502665
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenotypical analysis of ectoenzymes CD39/CD73 and adenosine receptor 2A in CD4
    Han L; Sugiyama H; Zhang Q; Yan K; Fang X; McCormick TS; Cooper KD; Huang Q
    Australas J Dermatol; 2018 Feb; 59(1):e31-e38. PubMed ID: 28295154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.
    Häusler SF; Montalbán del Barrio I; Strohschein J; Chandran PA; Engel JB; Hönig A; Ossadnik M; Horn E; Fischer B; Krockenberger M; Heuer S; Seida AA; Junker M; Kneitz H; Kloor D; Klotz KN; Dietl J; Wischhusen J
    Cancer Immunol Immunother; 2011 Oct; 60(10):1405-18. PubMed ID: 21638125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes.
    Clifford EE; Martin KA; Dalal P; Thomas R; Dubyak GR
    Am J Physiol; 1997 Sep; 273(3 Pt 1):C973-87. PubMed ID: 9316419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells.
    Yegutkin GG; Henttinen T; Samburski SS; Spychala J; Jalkanen S
    Biochem J; 2002 Oct; 367(Pt 1):121-8. PubMed ID: 12099890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased exosome production from tumour cell cultures using the Integra CELLine Culture System.
    Mitchell JP; Court J; Mason MD; Tabi Z; Clayton A
    J Immunol Methods; 2008 Jun; 335(1-2):98-105. PubMed ID: 18423480
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 50.