BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 21679153)

  • 1. Human liver enzymes responsible for metabolic elimination of tyramine; a vasopressor agent from daily food.
    Niwa T; Murayama N; Umeyama H; Shimizu M; Yamazaki H
    Drug Metab Lett; 2011 Aug; 5(3):216-9. PubMed ID: 21679153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics.
    Shen HW; Wu C; Jiang XL; Yu AM
    Biochem Pharmacol; 2010 Jul; 80(1):122-8. PubMed ID: 20206139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.
    Erickson DA; Hollfelder S; Tenge J; Gohdes M; Burkhardt JJ; Krieter PA
    Drug Metab Dispos; 2007 Dec; 35(12):2232-41. PubMed ID: 17881661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dopamine formation from tyramine by CYP2D6.
    Hiroi T; Imaoka S; Funae Y
    Biochem Biophys Res Commun; 1998 Aug; 249(3):838-43. PubMed ID: 9731223
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of genetic polymorphism on the metabolism of endogenous neuroactive substances, progesterone and p-tyramine, catalyzed by CYP2D6.
    Niwa T; Hiroi T; Tsuzuki D; Yamamoto S; Narimatsu S; Fukuda T; Azuma J; Funae Y
    Brain Res Mol Brain Res; 2004 Oct; 129(1-2):117-23. PubMed ID: 15469888
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
    Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD
    Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6.
    Shimada T; Tsumura F; Yamazaki H; Guengerich FP; Inoue K
    Pharmacogenetics; 2001 Mar; 11(2):143-56. PubMed ID: 11266079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation and deactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by cytochrome P450 enzymes and flavin-containing monooxygenases in common marmosets (Callithrix jacchus).
    Uehara S; Uno Y; Inoue T; Murayama N; Shimizu M; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2015 May; 43(5):735-42. PubMed ID: 25735838
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine.
    Yu AM; Granvil CP; Haining RL; Krausz KW; Corchero J; Küpfer A; Idle JR; Gonzalez FJ
    J Pharmacol Exp Ther; 2003 Feb; 304(2):539-46. PubMed ID: 12538805
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
    Yumibe N; Huie K; Chen KJ; Snow M; Clement RP; Cayen MN
    Biochem Pharmacol; 1996 Jan; 51(2):165-72. PubMed ID: 8615885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3.
    Okubo M; Narita M; Murayama N; Akimoto Y; Goto A; Yamazaki H
    Hum Psychopharmacol; 2016 Mar; 31(2):83-92. PubMed ID: 26856397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CYP2D6.10 present in human liver microsomes shows low catalytic activity and thermal stability.
    Nakamura K; Ariyoshi N; Yokoi T; Ohgiya S; Chida M; Nagashima K; Inoue K; Kodama T; Shimada N; Kamataki T
    Biochem Biophys Res Commun; 2002 May; 293(3):969-73. PubMed ID: 12051754
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of human cytochrome P450 isoforms involved in the 7-hydroxylation of chlorpromazine by human liver microsomes.
    Yoshii K; Kobayashi K; Tsumuji M; Tani M; Shimada N; Chiba K
    Life Sci; 2000; 67(2):175-84. PubMed ID: 10901285
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6.
    Mankowski DC
    Drug Metab Dispos; 1999 Sep; 27(9):1024-8. PubMed ID: 10460802
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
    Herraiz T; Guillén H; Arán VJ; Idle JR; Gonzalez FJ
    Toxicol Appl Pharmacol; 2006 Nov; 216(3):387-98. PubMed ID: 16870220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of cytochrome P450 2D6 by Sarpogrelate and its active metabolite, M-1, in human liver microsomes.
    Cho DY; Bae SH; Lee JK; Kim YW; Kim BT; Bae SK
    Drug Metab Dispos; 2014 Jan; 42(1):33-9. PubMed ID: 24167220
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6.
    Niwa T; Shizuku M; Yamano K
    Arch Biochem Biophys; 2017 Apr; 620():23-27. PubMed ID: 28347660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. (+)-bufuralol 1'-hydroxylation activity in human and rhesus monkey intestine and liver.
    Prueksaritanont T; Dwyer LM; Cribb AE
    Biochem Pharmacol; 1995 Oct; 50(9):1521-5. PubMed ID: 7503805
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes.
    Nakamura K; Yokoi T; Inoue K; Shimada N; Ohashi N; Kume T; Kamataki T
    Pharmacogenetics; 1996 Oct; 6(5):449-57. PubMed ID: 8946477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.