BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 21679375)

  • 1. Discovery of new antifungal leads via pharmacophore modeling and QSAR analysis of fungal N-myristoyl transferase inhibitors followed by in silico screening.
    Taha MO; Qandil AM; Al-Haraznah T; Khalaf RA; Zalloum H; Al-Bakri AG
    Chem Biol Drug Des; 2011 Sep; 78(3):391-407. PubMed ID: 21679375
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of new renin inhibitory leads via sequential pharmacophore modeling, QSAR analysis, in silico screening and in vitro evaluation.
    Al-Nadaf AH; Taha MO
    J Mol Graph Model; 2011 Apr; 29(6):843-64. PubMed ID: 21376648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of new β-D-galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening.
    Abdula AM; Khalaf RA; Mubarak MS; Taha MO
    J Comput Chem; 2011 Feb; 32(3):463-82. PubMed ID: 20730780
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration.
    Abu Khalaf R; Abu Sheikha G; Bustanji Y; Taha MO
    Eur J Med Chem; 2010 Apr; 45(4):1598-617. PubMed ID: 20116902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening.
    Taha MO; Atallah N; Al-Bakri AG; Paradis-Bleau C; Zalloum H; Younis KS; Levesque RC
    Bioorg Med Chem; 2008 Feb; 16(3):1218-35. PubMed ID: 17988876
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of new potent hormone sensitive lipase inhibitors.
    Taha MO; Dahabiyeh LA; Bustanji Y; Zalloum H; Saleh S
    J Med Chem; 2008 Oct; 51(20):6478-94. PubMed ID: 18808096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of DPP IV inhibitors by pharmacophore modeling and QSAR analysis followed by in silico screening.
    Al-Masri IM; Mohammad MK; Taha MO
    ChemMedChem; 2008 Nov; 3(11):1763-79. PubMed ID: 18989859
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacophore and QSAR modeling of estrogen receptor beta ligands and subsequent validation and in silico search for new hits.
    Taha MO; Tarairah M; Zalloum H; Abu-Sheikha G
    J Mol Graph Model; 2010 Jan; 28(5):383-400. PubMed ID: 19850503
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of new potent human protein tyrosine phosphatase inhibitors via pharmacophore and QSAR analysis followed by in silico screening.
    Taha MO; Bustanji Y; Al-Bakri AG; Yousef AM; Zalloum WA; Al-Masri IM; Atallah N
    J Mol Graph Model; 2007 Mar; 25(6):870-84. PubMed ID: 17035054
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Docking-based comparative intermolecular contacts analysis as new 3-D QSAR concept for validating docking studies and in silico screening: NMT and GP inhibitors as case studies.
    Taha MO; Habash M; Al-Hadidi Z; Al-Bakri A; Younis K; Sisan S
    J Chem Inf Model; 2011 Mar; 51(3):647-69. PubMed ID: 21370899
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors.
    Khanfar MA; Taha MO
    J Chem Inf Model; 2013 Oct; 53(10):2587-612. PubMed ID: 24050502
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
    Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA
    J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4D-QSAR analysis of a series of antifungal p450 inhibitors and 3D-pharmacophore comparisons as a function of alignment.
    Liu J; Pan D; Tseng Y; Hopfinger AJ
    J Chem Inf Comput Sci; 2003; 43(6):2170-9. PubMed ID: 14632469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elaborate ligand-based modeling reveals new nanomolar heat shock protein 90α inhibitors.
    Al-Sha'er MA; Taha MO
    J Chem Inf Model; 2010 Sep; 50(9):1706-23. PubMed ID: 20831219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unsupervised pharmacophore modeling combined with QSAR analyses revealed novel low micromolar SIRT2 inhibitors.
    Khanfar MA; Taha MO
    J Mol Recognit; 2017 Sep; 30(9):. PubMed ID: 28299833
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacophore modeling, quantitative structure-activity relationship analysis, and shape-complemented in silico screening allow access to novel influenza neuraminidase inhibitors.
    Abu Hammad AM; Taha MO
    J Chem Inf Model; 2009 Apr; 49(4):978-96. PubMed ID: 19341295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
    Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
    J Chem Inf Model; 2009 Apr; 49(4):1070-8. PubMed ID: 19296716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand-based modeling of diverse aryalkylamines yields new potent P-glycoprotein inhibitors.
    AlQudah DA; Zihlif MA; Taha MO
    Eur J Med Chem; 2016 Mar; 110():204-23. PubMed ID: 26840362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent beta-secretase inhibitory leads.
    Al-Nadaf A; Abu Sheikha G; Taha MO
    Bioorg Med Chem; 2010 May; 18(9):3088-115. PubMed ID: 20378363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and antifungal activity of isosteric analogues of benzoheterocyclic N-myristoyltransferase inhibitors.
    Sheng C; Xu H; Wang W; Cao Y; Dong G; Wang S; Che X; Ji H; Miao Z; Yao J; Zhang W
    Eur J Med Chem; 2010 Sep; 45(9):3531-40. PubMed ID: 20615585
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.