These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 21680182)

  • 41. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A; Brady NR
    J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Protein-protein recognition as a first step towards the inhibition of XIAP and Survivin anti-apoptotic proteins.
    Obiol-Pardo C; Granadino-Roldán JM; Rubio-Martinez J
    J Mol Recognit; 2008; 21(3):190-204. PubMed ID: 18438971
    [TBL] [Abstract][Full Text] [Related]  

  • 43. General Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC.
    Quast SA; Berger A; Buttstädt N; Friebel K; Schönherr R; Eberle J
    PLoS One; 2012; 7(6):e39290. PubMed ID: 22723988
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Design of small-molecule Smac mimetics as IAP antagonists.
    Wang S
    Curr Top Microbiol Immunol; 2011; 348():89-113. PubMed ID: 21072626
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs.
    Corti A; Milani M; Lecis D; Seneci P; de Rosa M; Mastrangelo E; Cossu F
    FEBS J; 2018 Sep; 285(17):3286-3298. PubMed ID: 30055105
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Bivalent SMAC Mimetics for Treating Cancer by Antagonizing Inhibitor of Apoptosis Proteins.
    Zhu H; Li Y; Liu Y; Han B
    ChemMedChem; 2019 Dec; 14(23):1951-1962. PubMed ID: 31692274
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro.
    Mao HL; Liu PS; Zheng JF; Zhang PH; Zhou LG; Xin G; Liu C
    Pharmacol Res; 2007 Dec; 56(6):483-92. PubMed ID: 18029193
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Bypassing the need for pre-sensitization of cancer cells for anticancer TRAIL therapy with secretion of novel cell penetrable form of Smac from hA-MSCs as cellular delivery vehicle.
    Khorashadizadeh M; Soleimani M; Khanahmad H; Fallah A; Naderi M; Khorramizadeh M
    Tumour Biol; 2015 Jun; 36(6):4213-21. PubMed ID: 25586349
    [TBL] [Abstract][Full Text] [Related]  

  • 49. The TwistDock workflow for evaluation of bivalent Smac mimetics targeting XIAP.
    Huang Q; Peng Y; Peng Y; Wei D; Wei Y; Feng S
    Drug Des Devel Ther; 2019; 13():1373-1388. PubMed ID: 31118573
    [No Abstract]   [Full Text] [Related]  

  • 50. Smac mimetics increase cancer cell response to chemotherapeutics in a TNF-α-dependent manner.
    Probst BL; Liu L; Ramesh V; Li L; Sun H; Minna JD; Wang L
    Cell Death Differ; 2010 Oct; 17(10):1645-54. PubMed ID: 20431601
    [TBL] [Abstract][Full Text] [Related]  

  • 51. X-linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery.
    Zhou J; Lu X; Tan TZ; Chng WJ
    Mol Oncol; 2018 Jan; 12(1):33-47. PubMed ID: 29063676
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Small-molecule SMAC mimetics as new cancer therapeutics.
    Bai L; Smith DC; Wang S
    Pharmacol Ther; 2014 Oct; 144(1):82-95. PubMed ID: 24841289
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors.
    Eyrisch S; Medina-Franco JL; Helms V
    J Mol Model; 2012 May; 18(5):2031-42. PubMed ID: 21877153
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.
    Ramachandiran S; Cain J; Liao A; He Y; Guo X; Boise LH; Fu H; Ratner L; Khoury HJ; Bernal-Mizrachi L
    Leuk Res; 2012 Jun; 36(6):784-90. PubMed ID: 22325366
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
    Lu J; McEachern D; Sun H; Bai L; Peng Y; Qiu S; Miller R; Liao J; Yi H; Liu M; Bellail A; Hao C; Sun SY; Ting AT; Wang S
    Mol Cancer Ther; 2011 May; 10(5):902-14. PubMed ID: 21372226
    [TBL] [Abstract][Full Text] [Related]  

  • 56. A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.
    Petrucci E; Pasquini L; Petronelli A; Saulle E; Mariani G; Riccioni R; Biffoni M; Ferretti G; Benedetti-Panici P; Cognetti F; Scambia G; Humphreys R; Peschle C; Testa U
    Gynecol Oncol; 2007 May; 105(2):481-92. PubMed ID: 17292950
    [TBL] [Abstract][Full Text] [Related]  

  • 57. X-linked inhibitor of apoptosis positive nuclear labeling: a new independent prognostic biomarker of breast invasive ductal carcinoma.
    Zhang Y; Zhu J; Tang Y; Li F; Zhou H; Peng B; Zhou C; Fu R
    Diagn Pathol; 2011 Jun; 6():49. PubMed ID: 21645409
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
    Fu J; Jin Y; Arend LJ
    J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.
    Sun H; Nikolovska-Coleska Z; Chen J; Yang CY; Tomita Y; Pan H; Yoshioka Y; Krajewski K; Roller PP; Wang S
    Bioorg Med Chem Lett; 2005 Feb; 15(3):793-7. PubMed ID: 15664859
    [TBL] [Abstract][Full Text] [Related]  

  • 60. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.
    Li L; Thomas RM; Suzuki H; De Brabander JK; Wang X; Harran PG
    Science; 2004 Sep; 305(5689):1471-4. PubMed ID: 15353805
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.