BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

467 related articles for article (PubMed ID: 21680894)

  • 1. Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.
    Bouchecareilh M; Higa A; Fribourg S; Moenner M; Chevet E
    FASEB J; 2011 Sep; 25(9):3115-29. PubMed ID: 21680894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.
    Gupta S; Deepti A; Deegan S; Lisbona F; Hetz C; Samali A
    PLoS Biol; 2010 Jul; 8(7):e1000410. PubMed ID: 20625543
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
    Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.
    Liu G; Guo H; Guo C; Zhao S; Gong D; Zhao Y
    Brain Res Bull; 2011 Jan; 84(1):94-102. PubMed ID: 20965234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T; Chu K; Kodama R; Byun S; Yoon KW; Hiraki M; Mandinova A; Lee SW
    Oncotarget; 2015 Aug; 6(24):19990-20001. PubMed ID: 26254280
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production.
    Kim S; Joe Y; Kim HJ; Kim YS; Jeong SO; Pae HO; Ryter SW; Surh YJ; Chung HT
    J Immunol; 2015 May; 194(9):4498-506. PubMed ID: 25821218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.
    Back SH; Lee K; Vink E; Kaufman RJ
    J Biol Chem; 2006 Jul; 281(27):18691-706. PubMed ID: 16644724
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress.
    Chen H; Yang H; Pan L; Wang W; Liu X; Ren X; Liu Y; Liu W; Zhang Y; Jiang L; Li K; Zhang B; Wang LX
    Biomed Pharmacother; 2016 Feb; 77():108-13. PubMed ID: 26796273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
    Gjymishka A; Su N; Kilberg MS
    Biochem J; 2009 Feb; 417(3):695-703. PubMed ID: 18840095
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
    So JS; Cho S; Min SH; Kimball SR; Lee AH
    Mol Cell Biol; 2015 Aug; 35(16):2761-70. PubMed ID: 26031337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
    Lee K; Tirasophon W; Shen X; Michalak M; Prywes R; Okada T; Yoshida H; Mori K; Kaufman RJ
    Genes Dev; 2002 Feb; 16(4):452-66. PubMed ID: 11850408
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress.
    Bright MD; Itzhak DN; Wardell CP; Morgan GJ; Davies FE
    Mol Cell Biol; 2015 Jun; 35(12):2186-202. PubMed ID: 25870107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A; Wang H; Li Y; Wang X; Chen D; Wu Z
    Viruses; 2017 Aug; 9(9):. PubMed ID: 28832521
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress.
    Li X; Sun S; Appathurai S; Sundaram A; Plumb R; Mariappan M
    Cell Rep; 2020 Dec; 33(13):108563. PubMed ID: 33378667
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.
    Lee R; Xu B; Rame JE; Felkin LE; Barton P; Dries DL
    J Am Heart Assoc; 2014 Dec; 3(6):e001104. PubMed ID: 25516437
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Endoplasmic reticulum stress preconditioning antagonizes low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF-κB pathway.
    Yu Y; Zhang L; Liu Q; Tang L; Sun H; Guo H
    Mol Med Rep; 2015 Mar; 11(3):2048-54. PubMed ID: 25405329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.
    Groenendyk J; Peng Z; Dudek E; Fan X; Mizianty MJ; Dufey E; Urra H; Sepulveda D; Rojas-Rivera D; Lim Y; Kim DH; Baretta K; Srikanth S; Gwack Y; Ahnn J; Kaufman RJ; Lee SK; Hetz C; Kurgan L; Michalak M
    Sci Signal; 2014 Jun; 7(329):ra54. PubMed ID: 24917591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.
    Arshad M; Ye Z; Gu X; Wong CK; Liu Y; Li D; Zhou L; Zhang Y; Bay WP; Yu VC; Li P
    J Biol Chem; 2013 Mar; 288(12):8726-8736. PubMed ID: 23378536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
    Zhang K; Wong HN; Song B; Miller CN; Scheuner D; Kaufman RJ
    J Clin Invest; 2005 Feb; 115(2):268-81. PubMed ID: 15690081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.