These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 21681606)

  • 1. Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice.
    Clarke JD; Hsu A; Williams DE; Dashwood RH; Stevens JF; Yamamoto M; Ho E
    Pharm Res; 2011 Dec; 28(12):3171-9. PubMed ID: 21681606
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.
    Xu C; Huang MT; Shen G; Yuan X; Lin W; Khor TO; Conney AH; Kong AN
    Cancer Res; 2006 Aug; 66(16):8293-6. PubMed ID: 16912211
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.
    Higgins LG; Kelleher MO; Eggleston IM; Itoh K; Yamamoto M; Hayes JD
    Toxicol Appl Pharmacol; 2009 Jun; 237(3):267-80. PubMed ID: 19303893
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells.
    Nair S; Barve A; Khor TO; Shen GX; Lin W; Chan JY; Cai L; Kong AN
    Acta Pharmacol Sin; 2010 Sep; 31(9):1223-40. PubMed ID: 20729872
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
    Thimmulappa RK; Mai KH; Srisuma S; Kensler TW; Yamamoto M; Biswal S
    Cancer Res; 2002 Sep; 62(18):5196-203. PubMed ID: 12234984
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane.
    Yang L; Palliyaguru DL; Kensler TW
    Semin Oncol; 2016 Feb; 43(1):146-153. PubMed ID: 26970133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.
    Morimitsu Y; Nakagawa Y; Hayashi K; Fujii H; Kumagai T; Nakamura Y; Osawa T; Horio F; Itoh K; Iida K; Yamamoto M; Uchida K
    J Biol Chem; 2002 Feb; 277(5):3456-63. PubMed ID: 11706044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.
    Cornblatt BS; Ye L; Dinkova-Kostova AT; Erb M; Fahey JW; Singh NK; Chen MS; Stierer T; Garrett-Mayer E; Argani P; Davidson NE; Talalay P; Kensler TW; Visvanathan K
    Carcinogenesis; 2007 Jul; 28(7):1485-90. PubMed ID: 17347138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.
    Clarke JD; Hsu A; Riedl K; Bella D; Schwartz SJ; Stevens JF; Ho E
    Pharmacol Res; 2011 Nov; 64(5):456-63. PubMed ID: 21816223
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S; Singh SV
    Cancer Res; 2005 Mar; 65(5):2035-43. PubMed ID: 15753404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety.
    Lan A; Li W; Liu Y; Xiong Z; Zhang X; Zhou S; Palko O; Chen H; Kapita M; Prigge JR; Schmidt EE; Chen X; Sun Z; Chen XL
    Oncotarget; 2016 Aug; 7(33):53502-53514. PubMed ID: 27447968
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane.
    Saw CL; Huang MT; Liu Y; Khor TO; Conney AH; Kong AN
    Mol Carcinog; 2011 Jun; 50(6):479-86. PubMed ID: 21557329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy.
    Gu J; Cheng Y; Wu H; Kong L; Wang S; Xu Z; Zhang Z; Tan Y; Keller BB; Zhou H; Wang Y; Xu Z; Cai L
    Diabetes; 2017 Feb; 66(2):529-542. PubMed ID: 27903744
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice.
    Cho HY; Miller-DeGraff L; Blankenship-Paris T; Wang X; Bell DA; Lih F; Deterding L; Panduri V; Morgan DL; Yamamoto M; Reddy AJ; Talalay P; Kleeberger SR
    Toxicol Appl Pharmacol; 2019 Feb; 364():29-44. PubMed ID: 30529165
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes.
    Wang H; Khor TO; Yang Q; Huang Y; Wu TY; Saw CL; Lin W; Androulakis IP; Kong AN
    Mol Pharm; 2012 Oct; 9(10):2819-27. PubMed ID: 22931102
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics of dietary cancer chemopreventive compound dibenzoylmethane in rats and the impact of nanoemulsion and genetic knockout of Nrf2 on its disposition.
    Lin W; Hong JL; Shen G; Wu RT; Wang Y; Huang MT; Newmark HL; Huang Q; Khor TO; Heimbach T; Kong AN
    Biopharm Drug Dispos; 2011 Mar; 32(2):65-75. PubMed ID: 21341276
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications.
    Keum YS
    Ann N Y Acad Sci; 2011 Jul; 1229():184-9. PubMed ID: 21793854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M; Itoh K; Yamamoto M; Chanas SA; Henderson CJ; McLellan LI; Wolf CR; Cavin C; Hayes JD
    Cancer Res; 2001 Apr; 61(8):3299-307. PubMed ID: 11309284
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease.
    Xue M; Qian Q; Adaikalakoteswari A; Rabbani N; Babaei-Jadidi R; Thornalley PJ
    Diabetes; 2008 Oct; 57(10):2809-17. PubMed ID: 18633117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
    Hu R; Xu C; Shen G; Jain MR; Khor TO; Gopalkrishnan A; Lin W; Reddy B; Chan JY; Kong AN
    Cancer Lett; 2006 Nov; 243(2):170-92. PubMed ID: 16516379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.