These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 2168397)

  • 1. A naturally occurring mutation of insulin receptor alanine 1134 impairs tyrosine kinase function and is associated with dominantly inherited insulin resistance.
    Moller DE; Yokota A; White MF; Pazianos AG; Flier JS
    J Biol Chem; 1990 Sep; 265(25):14979-85. PubMed ID: 2168397
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional properties of a naturally occurring Trp1200----Ser1200 mutation of the insulin receptor.
    Moller DE; Yokota A; Ginsberg-Fellner F; Flier JS
    Mol Endocrinol; 1990 Aug; 4(8):1183-91. PubMed ID: 1963473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles.
    Kusari J; Takata Y; Hatada E; Freidenberg G; Kolterman O; Olefsky JM
    J Biol Chem; 1991 Mar; 266(8):5260-7. PubMed ID: 2002058
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biologic activities of naturally occurring human insulin receptor mutations. Evidence that metabolic effects of insulin can be mediated by a kinase-deficient insulin receptor mutant.
    Moller DE; Benecke H; Flier JS
    J Biol Chem; 1991 Jun; 266(17):10995-1001. PubMed ID: 1645719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ala1048-->Asp mutation in the kinase domain of insulin receptor causes defective kinase activity and insulin resistance.
    Haruta T; Takata Y; Iwanishi M; Maegawa H; Imamura T; Egawa K; Itazu T; Kobayashi M
    Diabetes; 1993 Dec; 42(12):1837-44. PubMed ID: 8243830
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substitution of glutamic acid for alanine 1135 in the putative "catalytic loop" of the tyrosine kinase domain of the human insulin receptor. A mutation that impairs proteolytic processing into subunits and inhibits receptor tyrosine kinase activity.
    Cama A; de la Luz Sierra M; Quon MJ; Ottini L; Gorden P; Taylor SI
    J Biol Chem; 1993 Apr; 268(11):8060-9. PubMed ID: 8096518
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor.
    Taira M; Taira M; Hashimoto N; Shimada F; Suzuki Y; Kanatsuka A; Nakamura F; Ebina Y; Tatibana M; Makino H
    Science; 1989 Jul; 245(4913):63-6. PubMed ID: 2544997
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitution of glutamine for arginine 1131. A newly identified mutation in the catalytic loop of the tyrosine kinase domain of the human insulin receptor.
    Kishimoto M; Hashiramoto M; Yonezawa K; Shii K; Kazumi T; Kasuga M
    J Biol Chem; 1994 Apr; 269(15):11349-55. PubMed ID: 7512563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy).
    Vorwerk P; Christoffersen CT; Müller J; Vestergaard H; Pedersen O; De Meyts P
    Horm Res; 1999; 52(5):211-20. PubMed ID: 10844410
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
    Wilden PA; Kahn CR; Siddle K; White MF
    J Biol Chem; 1992 Aug; 267(23):16660-8. PubMed ID: 1322912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A mutation (Trp1193-->Leu1193) in the tyrosine kinase domain of the insulin receptor associated with type A syndrome of insulin resistance.
    Iwanishi M; Haruta T; Takata Y; Ishibashi O; Sasaoka T; Egawa K; Imamura T; Naitou K; Itazu T; Kobayashi M
    Diabetologia; 1993 May; 36(5):414-22. PubMed ID: 8390949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of glucose transport by a natural mutation in the human insulin receptor.
    Longo N; Langley SD; Griffin LD; Elsas LJ
    Proc Natl Acad Sci U S A; 1993 Jan; 90(1):60-4. PubMed ID: 8419945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity.
    White MF; Livingston JN; Backer JM; Lauris V; Dull TJ; Ullrich A; Kahn CR
    Cell; 1988 Aug; 54(5):641-9. PubMed ID: 2842060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A; Momomura K; Tobe K; Yamamoto-Honda R; Sakura H; Tamori Y; Kaburagi Y; Koshio O; Akanuma Y; Yazaki Y
    J Biol Chem; 1992 Jun; 267(18):12788-96. PubMed ID: 1618780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth.
    Wilden PA; Backer JM; Kahn CR; Cahill DA; Schroeder GJ; White MF
    Proc Natl Acad Sci U S A; 1990 May; 87(9):3358-62. PubMed ID: 2159147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
    Kan M; Kanai F; Iida M; Jinnouchi H; Todaka M; Imanaka T; Ito K; Nishioka Y; Ohnishi T; Kamohara S
    Diabetes; 1995 Sep; 44(9):1081-6. PubMed ID: 7657032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A domain of the insulin receptor required for endocytosis in rat fibroblasts.
    Thies RS; Webster NJ; McClain DA
    J Biol Chem; 1990 Jun; 265(17):10132-7. PubMed ID: 2161833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An in-frame insertion in exon 3 and a nonsense mutation in exon 2 of the insulin receptor gene associated with severe insulin resistance in a patient with Rabson-Mendenhall syndrome.
    Müller-Wieland D; van der Vorm ER; Streicher R; Krone W; Seemanova E; Dreyer M; Rüdiger HW; Rosipal SR; Maassen JA
    Diabetologia; 1993 Nov; 36(11):1168-74. PubMed ID: 8270132
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.
    Ebina Y; Araki E; Taira M; Shimada F; Mori M; Craik CS; Siddle K; Pierce SB; Roth RA; Rutter WJ
    Proc Natl Acad Sci U S A; 1987 Feb; 84(3):704-8. PubMed ID: 3101064
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A glycine-1008 to valine mutation in the insulin receptor in a woman with type A insulin resistance.
    Nozaki O; Suzuki Y; Shimada F; Hashimoto N; Taira M; Hatanaka Y; Notoya Y; Kanashiro O; Makino H; Yoshida S
    J Clin Endocrinol Metab; 1993 Jul; 77(1):169-72. PubMed ID: 8392082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.