BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 21684636)

  • 1. Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers.
    Abate C; Ferorelli S; Contino M; Marottoli R; Colabufo NA; Perrone R; Berardi F
    Eur J Med Chem; 2011 Sep; 46(9):4733-41. PubMed ID: 21684636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with added polar functionality and reduced lipophilicity for potential use as positron emission tomography radiotracers.
    Abate C; Niso M; Lacivita E; Mosier PD; Toscano A; Perrone R
    J Med Chem; 2011 Feb; 54(4):1022-32. PubMed ID: 21229979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
    J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
    Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
    J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.
    Abate C; Niso M; Marottoli R; Riganti C; Ghigo D; Ferorelli S; Ossato G; Perrone R; Lacivita E; Lamb DC; Berardi F
    J Med Chem; 2014 Apr; 57(8):3314-23. PubMed ID: 24697311
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.
    Xu J; Tu Z; Jones LA; Vangveravong S; Wheeler KT; Mach RH
    Eur J Pharmacol; 2005 Nov; 525(1-3):8-17. PubMed ID: 16289030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging.
    Selivanova SV; Toscano A; Abate C; Berardi F; Müller A; Krämer SD; Schibli R; Ametamey SM
    Nucl Med Biol; 2015 Apr; 42(4):399-405. PubMed ID: 25637276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents.
    Pati ML; Abate C; Contino M; Ferorelli S; Luisi R; Carroccia L; Niso M; Berardi F
    Eur J Med Chem; 2015 Jan; 89():691-700. PubMed ID: 25462276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
    Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
    J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Aminopyridine derivatives as potential σ(2) receptor antagonists.
    Abate C; Ferorelli S; Niso M; Lovicario C; Infantino V; Convertini P; Perrone R; Berardi F
    ChemMedChem; 2012 Oct; 7(10):1847-57. PubMed ID: 22890883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors.
    Kassiou M; Dannals RF; Liu X; Wong DF; Ravert HT; Scheffel UA
    Bioorg Med Chem; 2005 Jun; 13(11):3623-6. PubMed ID: 15862990
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
    Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands.
    Moussa IA; Banister SD; Beinat C; Giboureau N; Reynolds AJ; Kassiou M
    J Med Chem; 2010 Aug; 53(16):6228-39. PubMed ID: 20662542
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
    Zhang Y; Williams W; Torrence-Campbell C; Bowen WD; Rice KC
    J Med Chem; 1998 Dec; 41(25):4950-7. PubMed ID: 9836612
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
    Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
    Bonhaus DW; Loury DN; Jakeman LB; Hsu SA; To ZP; Leung E; Zeitung KD; Eglen RM; Wong EH
    J Pharmacol Exp Ther; 1994 Oct; 271(1):484-93. PubMed ID: 7965749
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
    Berardi F; Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R
    J Med Chem; 2005 Dec; 48(26):8237-44. PubMed ID: 16366605
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity.
    Abate C; Niso M; Contino M; Colabufo NA; Ferorelli S; Perrone R; Berardi F
    ChemMedChem; 2011 Jan; 6(1):73-80. PubMed ID: 21069657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.
    Abate C; Hornick JR; Spitzer D; Hawkins WG; Niso M; Perrone R; Berardi F
    J Med Chem; 2011 Aug; 54(16):5858-67. PubMed ID: 21744858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.