These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 21685363)

  • 1. A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
    Aragón E; Goerner N; Zaromytidou AI; Xi Q; Escobedo A; Massagué J; Macias MJ
    Genes Dev; 2011 Jun; 25(12):1275-88. PubMed ID: 21685363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Function of WW domains as phosphoserine- or phosphothreonine-binding modules.
    Lu PJ; Zhou XZ; Shen M; Lu KP
    Science; 1999 Feb; 283(5406):1325-8. PubMed ID: 10037602
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways.
    Aragón E; Goerner N; Xi Q; Gomes T; Gao S; Massagué J; Macias MJ
    Structure; 2012 Oct; 20(10):1726-36. PubMed ID: 22921829
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.
    Gao S; Alarcón C; Sapkota G; Rahman S; Chen PY; Goerner N; Macias MJ; Erdjument-Bromage H; Tempst P; Massagué J
    Mol Cell; 2009 Nov; 36(3):457-68. PubMed ID: 19917253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
    Alarcón C; Zaromytidou AI; Xi Q; Gao S; Yu J; Fujisawa S; Barlas A; Miller AN; Manova-Todorova K; Macias MJ; Sapkota G; Pan D; Massagué J
    Cell; 2009 Nov; 139(4):757-69. PubMed ID: 19914168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.
    Nakano A; Koinuma D; Miyazawa K; Uchida T; Saitoh M; Kawabata M; Hanai J; Akiyama H; Abe M; Miyazono K; Matsumoto T; Imamura T
    J Biol Chem; 2009 Mar; 284(10):6109-15. PubMed ID: 19122240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular interaction between Smurf1 WW2 domain and PPXY motifs of Smad1, Smad5, and Smad6--modeling and analysis.
    Sangadala S; Metpally RP; Reddy BV
    J Biomol Struct Dyn; 2007 Aug; 25(1):11-23. PubMed ID: 17676934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.
    Edwin F; Anderson K; Patel TB
    J Biol Chem; 2010 Jan; 285(1):255-64. PubMed ID: 19864419
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phospho-Smad1 modulation by nedd4 E3 ligase in BMP/TGF-β signaling.
    Kim BG; Lee JH; Yasuda J; Ryoo HM; Cho JY
    J Bone Miner Res; 2011 Jul; 26(7):1411-24. PubMed ID: 21308777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for phosphoserine-proline recognition by group IV WW domains.
    Verdecia MA; Bowman ME; Lu KP; Hunter T; Noel JP
    Nat Struct Biol; 2000 Aug; 7(8):639-43. PubMed ID: 10932246
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function.
    Lu PJ; Zhou XZ; Liou YC; Noel JP; Lu KP
    J Biol Chem; 2002 Jan; 277(4):2381-4. PubMed ID: 11723108
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription.
    Li L; Xin H; Xu X; Huang M; Zhang X; Chen Y; Zhang S; Fu XY; Chang Z
    Mol Cell Biol; 2004 Jan; 24(2):856-64. PubMed ID: 14701756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.
    Yan X; Liao H; Cheng M; Shi X; Lin X; Feng XH; Chen YG
    J Biol Chem; 2016 Jan; 291(1):382-92. PubMed ID: 26555259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.
    Morén A; Imamura T; Miyazono K; Heldin CH; Moustakas A
    J Biol Chem; 2005 Jun; 280(23):22115-23. PubMed ID: 15817471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation.
    Schelhorn C; Martín-Malpartida P; Suñol D; Macias MJ
    Sci Rep; 2015 Oct; 5():14990. PubMed ID: 26456073
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.
    Wiemuth D; Lott JS; Ly K; Ke Y; Teesdale-Spittle P; Snyder PM; McDonald FJ
    PLoS One; 2010 Aug; 5(8):e12163. PubMed ID: 20730100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functions of WW domains in the nucleus.
    Sudol M; Sliwa K; Russo T
    FEBS Lett; 2001 Feb; 490(3):190-5. PubMed ID: 11223034
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.
    Chong PA; Lin H; Wrana JL; Forman-Kay JD
    Proc Natl Acad Sci U S A; 2010 Oct; 107(43):18404-9. PubMed ID: 20937913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.
    Salah Z; Cohen S; Itzhaki E; Aqeilan RI
    Cell Cycle; 2013 Dec; 12(24):3817-23. PubMed ID: 24107629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.