BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

347 related articles for article (PubMed ID: 21685941)

  • 1. Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.
    Wang X; Venugopal C; Manoranjan B; McFarlane N; O'Farrell E; Nolte S; Gunnarsson T; Hollenberg R; Kwiecien J; Northcott P; Taylor MD; Hawkins C; Singh SK
    Oncogene; 2012 Jan; 31(2):187-99. PubMed ID: 21685941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion.
    Michael LE; Westerman BA; Ermilov AN; Wang A; Ferris J; Liu J; Blom M; Ellison DW; van Lohuizen M; Dlugosz AA
    Neoplasia; 2008 Dec; 10(12):1343-9, 5p following 1349. PubMed ID: 19048113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells.
    Venugopal C; Li N; Wang X; Manoranjan B; Hawkins C; Gunnarsson T; Hollenberg R; Klurfan P; Murty N; Kwiecien J; Farrokhyar F; Provias JP; Wynder C; Singh SK
    Stem Cell Res; 2012 Mar; 8(2):141-53. PubMed ID: 22265735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas.
    Leung C; Lingbeek M; Shakhova O; Liu J; Tanger E; Saremaslani P; Van Lohuizen M; Marino S
    Nature; 2004 Mar; 428(6980):337-41. PubMed ID: 15029199
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells.
    Manoranjan B; Wang X; Hallett RM; Venugopal C; Mack SC; McFarlane N; Nolte SM; Scheinemann K; Gunnarsson T; Hassell JA; Taylor MD; Lee C; Triscott J; Foster CM; Dunham C; Hawkins C; Dunn SE; Singh SK
    Stem Cells; 2013 Jul; 31(7):1266-77. PubMed ID: 23592496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bmi1 directly represses p21Waf1/Cip1 in Shh-induced proliferation of cerebellar granule cell progenitors.
    Subkhankulova T; Zhang X; Leung C; Marino S
    Mol Cell Neurosci; 2010 Oct; 45(2):151-62. PubMed ID: 20600931
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma.
    Chiba T; Miyagi S; Saraya A; Aoki R; Seki A; Morita Y; Yonemitsu Y; Yokosuka O; Taniguchi H; Nakauchi H; Iwama A
    Cancer Res; 2008 Oct; 68(19):7742-9. PubMed ID: 18829528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity.
    Lee SJ; Litan A; Li Z; Graves B; Lindsey S; Barwe SP; Langhans SA
    Mol Cancer; 2015 Aug; 14():159. PubMed ID: 26286140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
    Miele E; Po A; Begalli F; Antonucci L; Mastronuzzi A; Marras CE; Carai A; Cucchi D; Abballe L; Besharat ZM; Catanzaro G; Infante P; Di Marcotullio L; Canettieri G; De Smaele E; Screpanti I; Locatelli F; Ferretti E
    BMC Cancer; 2017 Jul; 17(1):488. PubMed ID: 28716052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
    Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
    Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.
    Vora P; Seyfrid M; Venugopal C; Qazi MA; Salim S; Isserlin R; Subapanditha M; O'Farrell E; Mahendram S; Singh M; Bakhshinyan D; Chokshi C; McFarlane N; Dvorkin-Gheva A; Brown KR; Murty N; Moffat J; Bader GD; Singh SK
    J Neurooncol; 2019 Jul; 143(3):417-428. PubMed ID: 31115870
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma.
    Ochiai H; Takenobu H; Nakagawa A; Yamaguchi Y; Kimura M; Ohira M; Okimoto Y; Fujimura Y; Koseki H; Kohno Y; Nakagawara A; Kamijo T
    Oncogene; 2010 May; 29(18):2681-90. PubMed ID: 20190806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.
    Shahi MH; Afzal M; Sinha S; Eberhart CG; Rey JA; Fan X; Castresana JS
    BMC Cancer; 2010 Nov; 10():614. PubMed ID: 21059263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.
    Elamin MH; Shinwari Z; Hendrayani SF; Al-Hindi H; Al-Shail E; Khafaga Y; Al-Kofide A; Aboussekhra A
    Mol Carcinog; 2010 Mar; 49(3):302-14. PubMed ID: 20025076
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD133+ cells from medulloblastoma and PNET cell lines are more resistant to cyclopamine inhibition of the sonic hedgehog signaling pathway than CD133- cells.
    Enguita-Germán M; Schiapparelli P; Rey JA; Castresana JS
    Tumour Biol; 2010 Oct; 31(5):381-90. PubMed ID: 20480407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
    Hor CHH; Lo JCW; Cham ALS; Leong WY; Goh ELK
    J Neurosci; 2021 Aug; 41(32):6850-6863. PubMed ID: 34210780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth.
    Di Magno L; Manzi D; D'Amico D; Coni S; Macone A; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Screpanti I; Agostinelli E; Gulino A; Canettieri G
    Cell Cycle; 2014; 13(21):3404-13. PubMed ID: 25485584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells.
    Ding X; Lin Q; Ensenat-Waser R; Rose-John S; Zenke M
    Stem Cells Dev; 2012 Jan; 21(1):121-32. PubMed ID: 21545235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
    Milla LA; Arros A; Espinoza N; Remke M; Kool M; Taylor MD; Pfister SM; Wainwright BJ; Palma V
    Int J Cancer; 2014 Jan; 134(1):21-31. PubMed ID: 23775842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hedgehog signaling promotes medulloblastoma survival via Bc/II.
    Bar EE; Chaudhry A; Farah MH; Eberhart CG
    Am J Pathol; 2007 Jan; 170(1):347-55. PubMed ID: 17200206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.