180 related articles for article (PubMed ID: 21686266)
1. p21-activated kinases in Erbb2-positive breast cancer: A new therapeutic target?
Arias-Romero LE; Chernoff J
Small GTPases; 2010 Sep; 1(2):124-128. PubMed ID: 21686266
[TBL] [Abstract][Full Text] [Related]
2. A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells.
Arias-Romero LE; Villamar-Cruz O; Pacheco A; Kosoff R; Huang M; Muthuswamy SK; Chernoff J
Oncogene; 2010 Oct; 29(43):5839-49. PubMed ID: 20711231
[TBL] [Abstract][Full Text] [Related]
3. Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.
Lim L; Manser E; Leung T; Hall C
Eur J Biochem; 1996 Dec; 242(2):171-85. PubMed ID: 8973630
[TBL] [Abstract][Full Text] [Related]
4. Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts.
Tang Y; Yu J; Field J
Mol Cell Biol; 1999 Mar; 19(3):1881-91. PubMed ID: 10022875
[TBL] [Abstract][Full Text] [Related]
5. Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Tabusa H; Brooks T; Massey AJ
Mol Cancer Res; 2013 Feb; 11(2):109-21. PubMed ID: 23233484
[TBL] [Abstract][Full Text] [Related]
6. Function of the Rho family GTPases in Ras-stimulated Raf activation.
Li W; Chong H; Guan KL
J Biol Chem; 2001 Sep; 276(37):34728-37. PubMed ID: 11457831
[TBL] [Abstract][Full Text] [Related]
7. Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration.
Bourguignon LY; Gilad E; Peyrollier K
J Biol Chem; 2007 Jul; 282(27):19426-41. PubMed ID: 17493932
[TBL] [Abstract][Full Text] [Related]
8. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.
Eblen ST; Slack JK; Weber MJ; Catling AD
Mol Cell Biol; 2002 Sep; 22(17):6023-33. PubMed ID: 12167697
[TBL] [Abstract][Full Text] [Related]
9. Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation.
Sundberg-Smith LJ; Doherty JT; Mack CP; Taylor JM
J Biol Chem; 2005 Jan; 280(3):2055-64. PubMed ID: 15542607
[TBL] [Abstract][Full Text] [Related]
10. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity.
Song P; Song B; Liu J; Wang X; Nan X; Wang J
Clin Transl Oncol; 2021 Apr; 23(4):892-901. PubMed ID: 32974862
[TBL] [Abstract][Full Text] [Related]
11. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
[TBL] [Abstract][Full Text] [Related]
12. Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.
Aksamitiene E; Achanta S; Kolch W; Kholodenko BN; Hoek JB; Kiyatkin A
Cell Signal; 2011 Nov; 23(11):1794-805. PubMed ID: 21726627
[TBL] [Abstract][Full Text] [Related]
13. SDF-1 synergistically enhances IL-3-induced activation of the Raf-1/MEK/Erk signaling pathway through activation of Rac and its effector Pak kinases to promote hematopoiesis and chemotaxis.
Arai A; Jin A; Yan W; Mizuchi D; Yamamoto K; Nanki T; Miura O
Cell Signal; 2005 Apr; 17(4):497-506. PubMed ID: 15601627
[TBL] [Abstract][Full Text] [Related]
14. p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.
Chow HY; Jubb AM; Koch JN; Jaffer ZM; Stepanova D; Campbell DA; Duron SG; O'Farrell M; Cai KQ; Klein-Szanto AJ; Gutkind JS; Hoeflich KP; Chernoff J
Cancer Res; 2012 Nov; 72(22):5966-75. PubMed ID: 22983922
[TBL] [Abstract][Full Text] [Related]
15. TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.
Oberst MD; Beberman SJ; Zhao L; Yin JJ; Ward Y; Kelly K
BMC Cancer; 2008 Jul; 8():189. PubMed ID: 18597688
[TBL] [Abstract][Full Text] [Related]
16. P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
Huynh N; Liu KH; Baldwin GS; He H
Biochim Biophys Acta; 2010 Sep; 1803(9):1106-13. PubMed ID: 20595063
[TBL] [Abstract][Full Text] [Related]
17. The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway.
Teramoto H; Crespo P; Coso OA; Igishi T; Xu N; Gutkind JS
J Biol Chem; 1996 Oct; 271(42):25731-4. PubMed ID: 8824197
[TBL] [Abstract][Full Text] [Related]
18. Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts.
Tang Y; Chen Z; Ambrose D; Liu J; Gibbs JB; Chernoff J; Field J
Mol Cell Biol; 1997 Aug; 17(8):4454-64. PubMed ID: 9234703
[TBL] [Abstract][Full Text] [Related]
19. Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
Arias-Romero LE; Villamar-Cruz O; Huang M; Hoeflich KP; Chernoff J
Cancer Res; 2013 Jun; 73(12):3671-82. PubMed ID: 23576562
[TBL] [Abstract][Full Text] [Related]
20. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens.
Zhong B; Jiang K; Gilvary DL; Epling-Burnette PK; Ritchey C; Liu J; Jackson RJ; Hong-Geller E; Wei S
Blood; 2003 Apr; 101(8):3240-8. PubMed ID: 12511425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]