BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 21686274)

  • 21. A novel role for mixed lineage kinase 3 (MLK3) in B-Raf activation and cell proliferation.
    Chadee DN; Kyriakis JM
    Cell Cycle; 2004 Oct; 3(10):1227-9. PubMed ID: 15467451
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens.
    Zhong B; Jiang K; Gilvary DL; Epling-Burnette PK; Ritchey C; Liu J; Jackson RJ; Hong-Geller E; Wei S
    Blood; 2003 Apr; 101(8):3240-8. PubMed ID: 12511425
    [TBL] [Abstract][Full Text] [Related]  

  • 23. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1.
    Olson MF; Ashworth A; Hall A
    Science; 1995 Sep; 269(5228):1270-2. PubMed ID: 7652575
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The role of mixed lineage kinase 3 (MLK3) in cancers.
    Ramachandraiah K; Thylur Puttalingaiah R
    Pharmacol Ther; 2022 Oct; 238():108269. PubMed ID: 36038020
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells.
    Blessing NA; Kasturirangan S; Zink EM; Schroyer AL; Chadee DN
    Cell Signal; 2017 Nov; 39():66-73. PubMed ID: 28757353
    [TBL] [Abstract][Full Text] [Related]  

  • 26. EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion.
    Misek SA; Chen J; Schroeder L; Rattanasinchai C; Sample A; Sarkaria JN; Gallo KA
    Mol Cancer Res; 2017 Aug; 15(8):1085-1095. PubMed ID: 28487380
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.
    Arozarena I; Matallanas D; Crespo P
    J Biol Chem; 2001 Jun; 276(24):21878-84. PubMed ID: 11285260
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Distinct cellular effects and interactions of the Rho-family GTPase TC10.
    Neudauer CL; Joberty G; Tatsis N; Macara IG
    Curr Biol; 1998 Oct; 8(21):1151-60. PubMed ID: 9799731
    [TBL] [Abstract][Full Text] [Related]  

  • 29. MLK3 Signaling in Cancer Invasion.
    Rattanasinchai C; Gallo KA
    Cancers (Basel); 2016 May; 8(5):. PubMed ID: 27213454
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway.
    Teramoto H; Crespo P; Coso OA; Igishi T; Xu N; Gutkind JS
    J Biol Chem; 1996 Oct; 271(42):25731-4. PubMed ID: 8824197
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells.
    Schroyer AL; Stimes NW; Abi Saab WF; Chadee DN
    Oncogene; 2018 Feb; 37(8):1031-1040. PubMed ID: 29084209
    [TBL] [Abstract][Full Text] [Related]  

  • 32. MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation.
    Chadee DN; Kyriakis JM
    Nat Cell Biol; 2004 Aug; 6(8):770-6. PubMed ID: 15258589
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells.
    Kim KY; Kim BC; Xu Z; Kim SJ
    J Biol Chem; 2004 Jul; 279(28):29478-84. PubMed ID: 15069087
    [TBL] [Abstract][Full Text] [Related]  

  • 34. MLK3 limits activated Galphaq signaling to Rho by binding to p63RhoGEF.
    Swenson-Fields KI; Sandquist JC; Rossol-Allison J; Blat IC; Wennerberg K; Burridge K; Means AR
    Mol Cell; 2008 Oct; 32(1):43-56. PubMed ID: 18851832
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
    Kissil JL; Wilker EW; Johnson KC; Eckman MS; Yaffe MB; Jacks T
    Mol Cell; 2003 Oct; 12(4):841-9. PubMed ID: 14580336
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field.
    Rajnicek AM; Foubister LE; McCaig CD
    J Cell Sci; 2006 May; 119(Pt 9):1723-35. PubMed ID: 16595546
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6.
    Korchnak AC; Zhan Y; Aguilar MT; Chadee DN
    Cell Signal; 2009 Nov; 21(11):1620-5. PubMed ID: 19586614
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.
    Mishra P; Senthivinayagam S; Rangasamy V; Sondarva G; Rana B
    Mol Endocrinol; 2010 Mar; 24(3):598-607. PubMed ID: 20150185
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis.
    Cronan MR; Nakamura K; Johnson NL; Granger DA; Cuevas BD; Wang JG; Mackman N; Scott JE; Dohlman HG; Johnson GL
    Oncogene; 2012 Aug; 31(34):3889-900. PubMed ID: 22139075
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.
    Liou GY; Zhang H; Miller EM; Seibold SA; Chen W; Gallo KA
    Biochem J; 2010 Apr; 427(3):435-43. PubMed ID: 20158498
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.