210 related articles for article (PubMed ID: 21691803)
61. Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.
T'jollyn H; Snoeys J; Vermeulen A; Michelet R; Cuyckens F; Mannens G; Van Peer A; Annaert P; Allegaert K; Van Bocxlaer J; Boussery K
AAPS J; 2015 Nov; 17(6):1376-87. PubMed ID: 26209290
[TBL] [Abstract][Full Text] [Related]
62. Modelling the pharmacokinetics of tramadol: on the difference between CYP2D6 extensive and poor metabolizers.
Di Patti F; Fanelli D; Pedersen RS; Giuliani C; Torricelli F
J Theor Biol; 2008 Oct; 254(3):568-74. PubMed ID: 18640130
[TBL] [Abstract][Full Text] [Related]
63. Impact of CYP2D6 and CYP2B6 phenotypes on the response to tramadol in patients with acute post-surgical pain.
Casajús A; Zubiaur P; Alday E; Soria-Chacartegui P; Saiz-Rodríguez M; Gutierrez L; Aragonés C; Campodónico D; Gómez-Fernández A; Navares-Gómez M; Villapalos-García G; Mejía-Abril G; Ochoa D; Abad-Santos F
Clin Transl Sci; 2024 Jan; 17(1):e13698. PubMed ID: 38140786
[TBL] [Abstract][Full Text] [Related]
64. Paroxetine, a cytochrome P450 2D6 inhibitor, diminishes the stereoselective O-demethylation and reduces the hypoalgesic effect of tramadol.
Laugesen S; Enggaard TP; Pedersen RS; Sindrup SH; Brøsen K
Clin Pharmacol Ther; 2005 Apr; 77(4):312-23. PubMed ID: 15903129
[TBL] [Abstract][Full Text] [Related]
65. Population pharmacokinetic modeling of tramadol and its O-desmethyl metabolite in plasma and breast milk.
Salman S; Sy SK; Ilett KF; Page-Sharp M; Paech MJ
Eur J Clin Pharmacol; 2011 Sep; 67(9):899-908. PubMed ID: 21394525
[TBL] [Abstract][Full Text] [Related]
66. Enantioselective analysis of unbound tramadol, O-desmethyltramadol and N-desmethyltramadol in plasma by ultrafiltration and LC-MS/MS: application to clinical pharmacokinetics.
de Moraes NV; Lauretti GR; Napolitano MN; Santos NR; Godoy AL; Lanchote VL
J Chromatogr B Analyt Technol Biomed Life Sci; 2012 Jan; 880(1):140-7. PubMed ID: 22173007
[TBL] [Abstract][Full Text] [Related]
67. Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction.
Hagelberg NM; Saarikoski T; Saari TI; Neuvonen M; Neuvonen PJ; Turpeinen M; Scheinin M; Laine K; Olkkola KT
Eur J Clin Pharmacol; 2013 Apr; 69(4):867-75. PubMed ID: 23099620
[TBL] [Abstract][Full Text] [Related]
68. Involvement of CYP2D6 and CYP2B6 on tramadol pharmacokinetics.
Saiz-Rodríguez M; Ochoa D; Román M; Zubiaur P; Koller D; Mejía G; Abad-Santos F
Pharmacogenomics; 2020 Jul; 21(10):663-675. PubMed ID: 32538291
[TBL] [Abstract][Full Text] [Related]
69. Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.
Allegaert K; Anderson BJ; Verbesselt R; Debeer A; de Hoon J; Devlieger H; Van Den Anker JN; Tibboel D
Br J Anaesth; 2005 Aug; 95(2):231-9. PubMed ID: 15951326
[TBL] [Abstract][Full Text] [Related]
70. Influence of Obesity and Type 2 Diabetes Mellitus on the Pharmacokinetics of Tramadol After Single Oral Dose Administration.
Porażka J; Szałek E; Połom W; Czajkowski M; Grabowski T; Matuszewski M; Grześkowiak E
Eur J Drug Metab Pharmacokinet; 2019 Aug; 44(4):579-584. PubMed ID: 30778911
[TBL] [Abstract][Full Text] [Related]
71. PHARMACOKINETICS OF TRAMADOL AND O-DESMETHYLTRAMADOL IN LOGGERHEAD SEA TURTLES (CARETTA CARETTA).
Norton TM; Cox S; Nelson SE; Kaylor M; Thomas R; Hupp A; Sladky KK
J Zoo Wildl Med; 2015 Jun; 46(2):262-5. PubMed ID: 26056877
[TBL] [Abstract][Full Text] [Related]
72. Evaluation of the Ecstasy influence on tramadol and its main metabolite plasma concentration in rats.
Jamali B; Sheikholeslami B; Hosseinzadeh Ardakani Y; Lavasani H; Rouini MR
Drug Metab Pers Ther; 2017 Sep; 32(3):137-145. PubMed ID: 28917081
[TBL] [Abstract][Full Text] [Related]
73. Effects of type 1 and type 2 diabetes on the pharmacokinetics of tramadol enantiomers in patients with neuropathic pain phenotyped as cytochrome P450 2D6 extensive metabolizers.
de Moraes NV; Lauretti GR; Lanchote VL
J Pharm Pharmacol; 2014 Sep; 66(9):1222-30. PubMed ID: 24717054
[TBL] [Abstract][Full Text] [Related]
74. Sequencing CYP2D6 for the detection of poor-metabolizers in post-mortem blood samples with tramadol.
Fonseca S; Amorim A; Costa HA; Franco J; Porto MJ; Santos JC; Dias M
Forensic Sci Int; 2016 Aug; 265():153-9. PubMed ID: 26926096
[TBL] [Abstract][Full Text] [Related]
75. Impact of CYP2D6 activity and cachexia progression on enantiomeric alteration of plasma tramadol and its demethylated metabolites and their relationships with central nervous system symptoms in head and neck cancer patients.
Suzuki K; Naito T; Tanaka H; Shibata K; Yamada Y; Itoh K; Kawakami J
Basic Clin Pharmacol Toxicol; 2021 Mar; 128(3):472-481. PubMed ID: 33131142
[TBL] [Abstract][Full Text] [Related]
76. Use of CYP2D6 substrates and inhibitors during pain management with analgesic opioids: Drug-drug interactions that lead to lack of analgesic effectiveness.
Muriel J; Escorial M; Carratalá C; Margarit C; Barrachina J; López A; Gallardo E; Kringen MK; Peiró AM
Biomed Pharmacother; 2024 Jul; 176():116882. PubMed ID: 38876046
[TBL] [Abstract][Full Text] [Related]
77. Validation of a high-performance liquid chromatography method for tramadol and o-desmethyltramadol in human plasma using solid-phase extraction.
Gan SH; Ismail R
J Chromatogr B Biomed Sci Appl; 2001 Aug; 759(2):325-35. PubMed ID: 11499486
[TBL] [Abstract][Full Text] [Related]
78. Simultaneous Determination of Tramadol and its Metabolite in Human Plasma by GC/MS.
Yılmaz B; Erdem AF
J AOAC Int; 2015; 98(1):56-61. PubMed ID: 25857879
[TBL] [Abstract][Full Text] [Related]
79. Influence of Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) polymorphisms on pain sensitivity and clinical response to weak opioid analgesics.
Zahari Z; Ismail R
Drug Metab Pharmacokinet; 2014; 29(1):29-43. PubMed ID: 23759977
[TBL] [Abstract][Full Text] [Related]
80. Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol.
Paar WD; Poche S; Gerloff J; Dengler HJ
Eur J Clin Pharmacol; 1997; 53(3-4):235-9. PubMed ID: 9476037
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
