136 related articles for article (PubMed ID: 21696964)
1. Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.
Kawamura T; Matsubara K; Otaka H; Tashiro E; Shindo K; Yanagita RC; Irie K; Imoto M
Bioorg Med Chem; 2011 Jul; 19(14):4377-85. PubMed ID: 21696964
[TBL] [Abstract][Full Text] [Related]
2. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
Nikolovska-Coleska Z; Xu L; Hu Z; Tomita Y; Li P; Roller PP; Wang R; Fang X; Guo R; Zhang M; Lippman ME; Yang D; Wang S
J Med Chem; 2004 May; 47(10):2430-40. PubMed ID: 15115387
[TBL] [Abstract][Full Text] [Related]
3. Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain.
Orzáez M; Gortat A; Sancho M; Carbajo RJ; Pineda-Lucena A; Palacios-Rodríguez Y; Pérez-Payá E
Apoptosis; 2011 May; 16(5):460-7. PubMed ID: 21340509
[TBL] [Abstract][Full Text] [Related]
4. Bivalent Smac mimetics with a diazabicyclic core as highly potent antagonists of XIAP and cIAP1/2 and novel anticancer agents.
Peng Y; Sun H; Lu J; Liu L; Cai Q; Shen R; Yang CY; Yi H; Wang S
J Med Chem; 2012 Jan; 55(1):106-14. PubMed ID: 22148838
[TBL] [Abstract][Full Text] [Related]
5. Chetomin induces degradation of XIAP and enhances TRAIL sensitivity in urogenital cancer cells.
Yano K; Horinaka M; Yoshida T; Yasuda T; Taniguchi H; Goda AE; Wakada M; Yoshikawa S; Nakamura T; Kawauchi A; Miki T; Sakai T
Int J Oncol; 2011 Feb; 38(2):365-74. PubMed ID: 21165560
[TBL] [Abstract][Full Text] [Related]
6. Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Checinska A; Hoogeland BS; Rodriguez JA; Giaccone G; Kruyt FA
Exp Cell Res; 2007 Apr; 313(6):1215-24. PubMed ID: 17291493
[TBL] [Abstract][Full Text] [Related]
7. Screening multicomponent reactions for X-linked inhibitor of apoptosis-baculoviral inhibitor of apoptosis protein repeats domain binder.
Monfardini I; Huang JW; Beck B; Cellitti JF; Pellecchia M; Dömling A
J Med Chem; 2011 Feb; 54(3):890-900. PubMed ID: 21241056
[TBL] [Abstract][Full Text] [Related]
8. Total synthesis of (+)-trans-trikentrin A.
Tébéka IR; Longato GB; Craveiro MV; de Carvalho JE; Ruiz AL; Silva LF
Chemistry; 2012 Dec; 18(52):16890-901. PubMed ID: 23124578
[TBL] [Abstract][Full Text] [Related]
9. Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.
Vogler M; Walczak H; Stadel D; Haas TL; Genze F; Jovanovic M; Bhanot U; Hasel C; Möller P; Gschwend JE; Simmet T; Debatin KM; Fulda S
Cancer Res; 2009 Mar; 69(6):2425-34. PubMed ID: 19258513
[TBL] [Abstract][Full Text] [Related]
10. Structure and cytotoxicity of phidianidines A and B: first finding of 1,2,4-oxadiazole system in a marine natural product.
Carbone M; Li Y; Irace C; Mollo E; Castelluccio F; Di Pascale A; Cimino G; Santamaria R; Guo YW; Gavagnin M
Org Lett; 2011 May; 13(10):2516-9. PubMed ID: 21506595
[TBL] [Abstract][Full Text] [Related]
11. Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis.
Hörnle M; Peters N; Thayaparasingham B; Vörsmann H; Kashkar H; Kulms D
Oncogene; 2011 Feb; 30(5):575-87. PubMed ID: 20856198
[TBL] [Abstract][Full Text] [Related]
12. Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells.
Shi RX; Ong CN; Shen HM
Cancer Res; 2005 Sep; 65(17):7815-23. PubMed ID: 16140950
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein.
Chen J; Nikolovska-Coleska Z; Wang G; Qiu S; Wang S
Bioorg Med Chem Lett; 2006 Nov; 16(22):5805-8. PubMed ID: 16962773
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of screening libraries based on the muurolane natural product scaffold.
Barnes EC; Choomuenwai V; Andrews KT; Quinn RJ; Davis RA
Org Biomol Chem; 2012 May; 10(20):4015-23. PubMed ID: 22422350
[TBL] [Abstract][Full Text] [Related]
15. Cell-penetrating peptide-conjugated XIAP-inhibitory cyclic hexapeptides enter into Jurkat cells and inhibit cell proliferation.
Sasaki Y; Minamizawa M; Ambo A; Sugawara S; Ogawa Y; Nitta K
FEBS J; 2008 Dec; 275(23):6011-21. PubMed ID: 19016849
[TBL] [Abstract][Full Text] [Related]
16. Total synthesis, stereochemical assignment, and biological activity of all known (-)-trigonoliimines.
Han S; Morrison KC; Hergenrother PJ; Movassaghi M
J Org Chem; 2014 Jan; 79(2):473-86. PubMed ID: 24127681
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 2,5-diaminobenzamide derivatives as anti-proliferating agents.
Lee SH; Park JW; Hong JE; Park JW; Lee J
Arch Pharm Res; 2009 Jun; 32(6):803-12. PubMed ID: 19557356
[TBL] [Abstract][Full Text] [Related]
18. In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3.
Pfisterer PH; Shen C; Nikolovska-Coleska Z; Schyschka L; Schuster D; Rudy A; Wolber G; Vollmar AM; Rollinger JM; Stuppner H
Bioorg Med Chem; 2011 Jan; 19(2):1002-9. PubMed ID: 21087868
[TBL] [Abstract][Full Text] [Related]
19. The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents.
Haney KM; Zhang F; Arnatt CK; Yuan Y; Li G; Ware JL; Gewirtz DA; Zhang Y
Bioorg Med Chem Lett; 2011 Sep; 21(18):5159-63. PubMed ID: 21820898
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and in vitro evaluation of imidazole-based wakayin analogues.
Hoang H; Huang X; Skibo EB
Org Biomol Chem; 2008 Sep; 6(17):3059-64. PubMed ID: 18698463
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
