BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 21700875)

  • 1. Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.
    Kim N; Huang SN; Williams JS; Li YC; Clark AB; Cho JE; Kunkel TA; Pommier Y; Jinks-Robertson S
    Science; 2011 Jun; 332(6037):1561-4. PubMed ID: 21700875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast.
    Cho JE; Kim N; Li YC; Jinks-Robertson S
    DNA Repair (Amst); 2013 Mar; 12(3):205-11. PubMed ID: 23305949
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular biology. A new twist for topoisomerase.
    Cerritelli SM; Chon H; Crouch RJ
    Science; 2011 Jun; 332(6037):1510-1. PubMed ID: 21700860
    [No Abstract]   [Full Text] [Related]  

  • 4. High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.
    Cerritelli SM; Iranzo J; Sharma S; Chabes A; Crouch RJ; Tollervey D; El Hage A
    Nucleic Acids Res; 2020 May; 48(8):4274-4297. PubMed ID: 32187369
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA.
    Williams JS; Smith DJ; Marjavaara L; Lujan SA; Chabes A; Kunkel TA
    Mol Cell; 2013 Mar; 49(5):1010-5. PubMed ID: 23375499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides.
    Williams JS; Kunkel TA
    Methods Mol Biol; 2018; 1703():241-257. PubMed ID: 29177746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis.
    Cerritelli SM; El Hage A
    Curr Genet; 2020 Dec; 66(6):1073-1084. PubMed ID: 32886170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Topoisomerase I alone is sufficient to produce short DNA deletions and can also reverse nicks at ribonucleotide sites.
    Huang SY; Ghosh S; Pommier Y
    J Biol Chem; 2015 May; 290(22):14068-76. PubMed ID: 25887397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter.
    Cho JE; Kim N; Jinks-Robertson S
    Nucleic Acids Res; 2015 Oct; 43(19):9306-13. PubMed ID: 26271994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation.
    Yadav P; Owiti N; Kim N
    Nucleic Acids Res; 2016 Jan; 44(2):718-29. PubMed ID: 26527723
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Topoisomerase I and Genome Stability: The Good and the Bad.
    Cho JE; Jinks-Robertson S
    Methods Mol Biol; 2018; 1703():21-45. PubMed ID: 29177731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks.
    Huang SN; Williams JS; Arana ME; Kunkel TA; Pommier Y
    EMBO J; 2017 Feb; 36(3):361-373. PubMed ID: 27932446
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.
    Cho JE; Jinks-Robertson S
    J Mol Biol; 2017 Oct; 429(21):3156-3167. PubMed ID: 27511624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apn2 resolves blocked 3' ends and suppresses Top1-induced mutagenesis at genomic rNMP sites.
    Li F; Wang Q; Seol JH; Che J; Lu X; Shim EY; Lee SE; Niu H
    Nat Struct Mol Biol; 2019 Mar; 26(3):155-163. PubMed ID: 30778235
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Both R-loop removal and ribonucleotide excision repair activities of RNase H2 contribute substantially to chromosome stability.
    Cornelio DA; Sedam HN; Ferrarezi JA; Sampaio NM; Argueso JL
    DNA Repair (Amst); 2017 Apr; 52():110-114. PubMed ID: 28268090
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides.
    Sparks JL; Burgers PM
    EMBO J; 2015 May; 34(9):1259-69. PubMed ID: 25777529
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo.
    Cho JE; Huang SY; Burgers PM; Shuman S; Pommier Y; Jinks-Robertson S
    Nucleic Acids Res; 2016 Sep; 44(16):7714-21. PubMed ID: 27257064
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of camptothecin or TOP1 overexpression on genetic stability in Saccharomyces cerevisiae.
    Sloan R; Huang SN; Pommier Y; Jinks-Robertson S
    DNA Repair (Amst); 2017 Nov; 59():69-75. PubMed ID: 28961461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H.
    Shen Y; Koh KD; Weiss B; Storici F
    Nat Struct Mol Biol; 2011 Dec; 19(1):98-104. PubMed ID: 22139012
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of RNase H2 in processing ribonucleotides incorporated during DNA replication.
    Williams JS; Gehle DB; Kunkel TA
    DNA Repair (Amst); 2017 May; 53():52-58. PubMed ID: 28325498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.