268 related articles for article (PubMed ID: 21702481)
1. Molecular dynamics simulation and binding energy calculation for estimation of oligonucleotide duplex thermostability in RNA-based therapeutics.
Shen L; Johnson TL; Clugston S; Huang H; Butenhof KJ; Stanton RV
J Chem Inf Model; 2011 Aug; 51(8):1957-65. PubMed ID: 21702481
[TBL] [Abstract][Full Text] [Related]
2. Sequence-dependent thermodynamic parameters for locked nucleic acid (LNA)-DNA duplex formation.
McTigue PM; Peterson RJ; Kahn JD
Biochemistry; 2004 May; 43(18):5388-405. PubMed ID: 15122905
[TBL] [Abstract][Full Text] [Related]
3. Carba-LNA-5MeC/A/G/T modified oligos show nucleobase-specific modulation of 3'-exonuclease activity, thermodynamic stability, RNA selectivity, and RNase H elicitation: synthesis and biochemistry.
Upadhayaya R; Deshpande SG; Li Q; Kardile RA; Sayyed AY; Kshirsagar EK; Salunke RV; Dixit SS; Zhou C; Földesi A; Chattopadhyaya J
J Org Chem; 2011 Jun; 76(11):4408-31. PubMed ID: 21500818
[TBL] [Abstract][Full Text] [Related]
4. Oligonucleotide charge reversal: 2'-O-lysylaminohexyl modified oligonucleotides.
Winkler J; Noe CR
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):939-42. PubMed ID: 18058513
[TBL] [Abstract][Full Text] [Related]
5. Determination of affinity constants of locked nucleic acid (LNA) and DNA duplex formation using label free sensor technology.
Möhrle BP; Kumpf M; Gauglitz G
Analyst; 2005 Dec; 130(12):1634-8. PubMed ID: 16284662
[TBL] [Abstract][Full Text] [Related]
6. Thermodynamics of DNA-RNA heteroduplex formation: effects of locked nucleic acid nucleotides incorporated into the DNA strand.
Kaur H; Wengel J; Maiti S
Biochemistry; 2008 Jan; 47(4):1218-27. PubMed ID: 18171024
[TBL] [Abstract][Full Text] [Related]
7. NMR studies of fully modified locked nucleic acid (LNA) hybrids: solution structure of an LNA:RNA hybrid and characterization of an LNA:DNA hybrid.
Nielsen KE; Rasmussen J; Kumar R; Wengel J; Jacobsen JP; Petersen M
Bioconjug Chem; 2004; 15(3):449-57. PubMed ID: 15149171
[TBL] [Abstract][Full Text] [Related]
8. Thermodynamic and kinetic characterization of duplex formation between 2'-O, 4'-C-methylene-modified oligoribonucleotides, DNA and RNA.
Christensen U
Biosci Rep; 2007 Dec; 27(6):327-33. PubMed ID: 17592767
[TBL] [Abstract][Full Text] [Related]
9. Conformation of formacetal and 3'-thioformacetal nucleotide linkers and stability of their antisense RNA.DNA hybrid duplexes.
Rice JS; Gao X
Biochemistry; 1997 Jan; 36(2):399-411. PubMed ID: 9003193
[TBL] [Abstract][Full Text] [Related]
10. Comparison of the thermodynamics and base-pair dynamics of a full LNA:DNA duplex and of the isosequential DNA:DNA duplex.
Bruylants G; Boccongelli M; Snoussi K; Bartik K
Biochemistry; 2009 Sep; 48(35):8473-82. PubMed ID: 19670874
[TBL] [Abstract][Full Text] [Related]
11. Recognition of RNA by amide modified backbone nucleic acids: molecular dynamics simulations of DNA-RNA hybrids in aqueous solution.
Nina M; Fonné-Pfister R; Beaudegnies R; Chekatt H; Jung PM; Murphy-Kessabi F; De Mesmaeker A; Wendeborn S
J Am Chem Soc; 2005 Apr; 127(16):6027-38. PubMed ID: 15839703
[TBL] [Abstract][Full Text] [Related]
12. Atomistic investigation of the effect of incremental modification of deoxyribose sugars by locked nucleic acid (β-D-LNA and α-L-LNA) moieties on the structures and thermodynamics of DNA-RNA hybrid duplexes.
Suresh G; Priyakumar UD
J Phys Chem B; 2014 Jun; 118(22):5853-63. PubMed ID: 24845216
[TBL] [Abstract][Full Text] [Related]
13. Role of the heat capacity change in understanding and modeling melting thermodynamics of complementary duplexes containing standard and nucleobase-modified LNA.
Hughesman CB; Turner RF; Haynes CA
Biochemistry; 2011 Jun; 50(23):5354-68. PubMed ID: 21548576
[TBL] [Abstract][Full Text] [Related]
14. Double sugar and phosphate backbone-constrained nucleotides: synthesis, structure, stability, and their incorporation into oligodeoxynucleotides.
Zhou C; Plashkevych O; Chattopadhyaya J
J Org Chem; 2009 May; 74(9):3248-65. PubMed ID: 19348480
[TBL] [Abstract][Full Text] [Related]
15. Structures, dynamics, and stabilities of fully modified locked nucleic acid (β-D-LNA and α-L-LNA) duplexes in comparison to pure DNA and RNA duplexes.
Suresh G; Priyakumar UD
J Phys Chem B; 2013 May; 117(18):5556-64. PubMed ID: 23617391
[TBL] [Abstract][Full Text] [Related]
16. CD and melting curves structural studies of the tandem DNA complex formed with oligonucleotides carrying photoactive and sensitizing groups in the nick region.
Koval VV; Pyshnyi D; Fedorova O
J Biomol Struct Dyn; 2001 Dec; 19(3):515-26. PubMed ID: 11790149
[TBL] [Abstract][Full Text] [Related]
17. Locked nucleic acids: a promising molecular family for gene-function analysis and antisense drug development.
Orum H; Wengel J
Curr Opin Mol Ther; 2001 Jun; 3(3):239-43. PubMed ID: 11497347
[TBL] [Abstract][Full Text] [Related]
18. Effects of locked nucleic acid substitutions on the stability of oligonucleotide hairpins.
Hull C; Szewcyk C; St John PM
Nucleosides Nucleotides Nucleic Acids; 2012; 31(1):28-41. PubMed ID: 22257208
[TBL] [Abstract][Full Text] [Related]
19. Locked nucleic acids: promising nucleic acid analogs for therapeutic applications.
Veedu RN; Wengel J
Chem Biodivers; 2010 Mar; 7(3):536-42. PubMed ID: 20232325
[TBL] [Abstract][Full Text] [Related]
20. LNA-antisense rivals siRNA for gene silencing.
Jepsen JS; Wengel J
Curr Opin Drug Discov Devel; 2004 Mar; 7(2):188-94. PubMed ID: 15603252
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
