BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 21704157)

  • 1. Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro.
    Peake KB; Campenot RB; Vance DE; Vance JE
    Biochim Biophys Acta; 2011 Sep; 1812(9):1121-9. PubMed ID: 21704157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick disease type C.
    Boyle BR; Melli SE; Altreche RS; Padron ZM; Yousufzai FAK; Kim S; Vasquez MD; Carone DM; Carone BR; Soto I
    Development; 2020 Aug; 147(21):. PubMed ID: 32611604
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decreased estradiol release from astrocytes contributes to the neurodegeneration in a mouse model of Niemann-Pick disease type C.
    Chen G; Li HM; Chen YR; Gu XS; Duan S
    Glia; 2007 Nov; 55(15):1509-18. PubMed ID: 17705200
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia.
    Baudry M; Yao Y; Simmons D; Liu J; Bi X
    Exp Neurol; 2003 Dec; 184(2):887-903. PubMed ID: 14769381
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons.
    Karten B; Vance DE; Campenot RB; Vance JE
    J Neurochem; 2002 Dec; 83(5):1154-63. PubMed ID: 12437586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation.
    Dominko K; Rastija A; Sobocanec S; Vidatic L; Meglaj S; Lovincic Babic A; Hutter-Paier B; Colombo AV; Lichtenthaler SF; Tahirovic S; Hecimovic S
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
    Colombo A; Dinkel L; Müller SA; Sebastian Monasor L; Schifferer M; Cantuti-Castelvetri L; König J; Vidatic L; Bremova-Ertl T; Lieberman AP; Hecimovic S; Simons M; Lichtenthaler SF; Strupp M; Schneider SA; Tahirovic S
    Nat Commun; 2021 Feb; 12(1):1158. PubMed ID: 33627648
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The autophagic defect in Niemann-Pick disease type C neurons differs from somatic cells and reduces neuronal viability.
    Meske V; Erz J; Priesnitz T; Ohm TG
    Neurobiol Dis; 2014 Apr; 64():88-97. PubMed ID: 24412309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cathepsin S contributes to microglia-mediated olfactory dysfunction through the regulation of Cx3cl1-Cx3cr1 axis in a Niemann-Pick disease type C1 model.
    Seo Y; Kim HS; Kang I; Choi SW; Shin TH; Shin JH; Lee BC; Lee JY; Kim JJ; Kook MG; Kang KS
    Glia; 2016 Dec; 64(12):2291-2305. PubMed ID: 27687148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice.
    Peake KB; Vance JE
    J Biol Chem; 2012 Mar; 287(12):9290-8. PubMed ID: 22277650
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C.
    Kavetsky L; Green KK; Boyle BR; Yousufzai FAK; Padron ZM; Melli SE; Kuhnel VL; Jackson HM; Blanco RE; Howell GR; Soto I
    Sci Rep; 2019 Oct; 9(1):14722. PubMed ID: 31605022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Single Cell Transcriptome Analysis of Niemann-Pick Disease, Type C1 Cerebella.
    Cougnoux A; Yerger JC; Fellmeth M; Serra-Vinardell J; Martin K; Navid F; Iben J; Wassif CA; Cawley NX; Porter FD
    Int J Mol Sci; 2020 Jul; 21(15):. PubMed ID: 32731618
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1.
    Prabhu AV; Kang I; De Pace R; Wassif CA; Fujiwara H; Kell P; Jiang X; Ory DS; Bonifacino JS; Ward ME; Porter FD
    BMC Biol; 2021 Oct; 19(1):218. PubMed ID: 34592985
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lysosomal vitamin E accumulation in Niemann-Pick type C disease.
    Yévenes LF; Klein A; Castro JF; Marín T; Leal N; Leighton F; Alvarez AR; Zanlungo S
    Biochim Biophys Acta; 2012 Feb; 1822(2):150-60. PubMed ID: 22120593
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of liver disease and lipid metabolism in the Niemann-Pick C1 mouse.
    Garver WS; Jelinek D; Oyarzo JN; Flynn J; Zuckerman M; Krishnan K; Chung BH; Heidenreich RA
    J Cell Biochem; 2007 May; 101(2):498-516. PubMed ID: 17216601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anatomically defined neuron-based rescue of neurodegenerative Niemann-Pick type C disorder.
    Lopez ME; Klein AD; Dimbil UJ; Scott MP
    J Neurosci; 2011 Mar; 31(12):4367-78. PubMed ID: 21430138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy.
    Yu W; Ko M; Yanagisawa K; Michikawa M
    J Biol Chem; 2005 Jul; 280(29):27296-302. PubMed ID: 15919659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activation in the NPC brain.
    Suzuki M; Sugimoto Y; Ohsaki Y; Ueno M; Kato S; Kitamura Y; Hosokawa H; Davies JP; Ioannou YA; Vanier MT; Ohno K; Ninomiya H
    J Neurosci; 2007 Feb; 27(8):1879-91. PubMed ID: 17314284
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons.
    Karten B; Vance DE; Campenot RB; Vance JE
    J Biol Chem; 2003 Feb; 278(6):4168-75. PubMed ID: 12458210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain.
    Reid PC; Sakashita N; Sugii S; Ohno-Iwashita Y; Shimada Y; Hickey WF; Chang TY
    J Lipid Res; 2004 Mar; 45(3):582-91. PubMed ID: 14703504
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.