These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 21707050)

  • 21. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.
    Murakami S; Nakashima R; Yamashita E; Matsumoto T; Yamaguchi A
    Nature; 2006 Sep; 443(7108):173-9. PubMed ID: 16915237
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli.
    Gerken H; Misra R
    Mol Microbiol; 2004 Nov; 54(3):620-31. PubMed ID: 15491355
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB.
    Kinana AD; Vargiu AV; Nikaido H
    Biochemistry; 2013 Nov; 52(46):8342-51. PubMed ID: 24205856
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dissecting the function of a protruding loop in AcrB trimerization.
    Fang J; Yu L; Wu M; Wei Y
    J Biomol Struct Dyn; 2013 Apr; 31(4):385-92. PubMed ID: 22877148
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump.
    Vargiu AV; Ramaswamy VK; Malvacio I; Malloci G; Kleinekathöfer U; Ruggerone P
    Biochim Biophys Acta Gen Subj; 2018 Apr; 1862(4):836-845. PubMed ID: 29339082
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of
    Atzori A; Malloci G; Cardamone F; Bosin A; Vargiu AV; Ruggerone P
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32013182
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Stepwise substrate translocation mechanism revealed by free energy calculations of doxorubicin in the multidrug transporter AcrB.
    Zuo Z; Wang B; Weng J; Wang W
    Sci Rep; 2015 Sep; 5():13905. PubMed ID: 26365278
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
    Sjuts H; Vargiu AV; Kwasny SM; Nguyen ST; Kim HS; Ding X; Ornik AR; Ruggerone P; Bowlin TL; Nikaido H; Pos KM; Opperman TJ
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3509-14. PubMed ID: 26976576
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Drug uptake pathways of multidrug transporter AcrB studied by molecular simulations and site-directed mutagenesis experiments.
    Yao XQ; Kimura N; Murakami S; Takada S
    J Am Chem Soc; 2013 May; 135(20):7474-85. PubMed ID: 23627437
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate.
    Ababou A; Koronakis V
    PLoS One; 2016; 11(7):e0159154. PubMed ID: 27403665
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.
    Mowla R; Wang Y; Ma S; Venter H
    Biochim Biophys Acta Biomembr; 2018 Apr; 1860(4):878-886. PubMed ID: 28890187
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
    Eicher T; Cha HJ; Seeger MA; Brandstätter L; El-Delik J; Bohnert JA; Kern WV; Verrey F; Grütter MG; Diederichs K; Pos KM
    Proc Natl Acad Sci U S A; 2012 Apr; 109(15):5687-92. PubMed ID: 22451937
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Folding of AcrB Subunit Precedes Trimerization.
    Lu W; Zhong M; Wei Y
    J Mol Biol; 2011 Aug; 411(1):264-74. PubMed ID: 21664361
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Substrate-dependent transport mechanism in AcrB of multidrug resistant bacteria.
    Jewel Y; Van Dinh Q; Liu J; Dutta P
    Proteins; 2020 Jul; 88(7):853-864. PubMed ID: 31998988
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Crucial role of Asp408 in the proton translocation pathway of multidrug transporter AcrB: evidence from site-directed mutagenesis and carbodiimide labeling.
    Seeger MA; von Ballmoos C; Verrey F; Pos KM
    Biochemistry; 2009 Jun; 48(25):5801-12. PubMed ID: 19425588
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Vestibules are part of the substrate path in the multidrug efflux transporter AcrB of Escherichia coli.
    Husain F; Bikhchandani M; Nikaido H
    J Bacteriol; 2011 Oct; 193(20):5847-9. PubMed ID: 21856849
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Substrate path in the AcrB multidrug efflux pump of Escherichia coli.
    Husain F; Nikaido H
    Mol Microbiol; 2010 Oct; 78(2):320-30. PubMed ID: 20804453
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Functional relevance of AcrB Trimerization in pump assembly and substrate binding.
    Lu W; Zhong M; Chai Q; Wang Z; Yu L; Wei Y
    PLoS One; 2014; 9(2):e89143. PubMed ID: 24551234
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.
    Seeger MA; Schiefner A; Eicher T; Verrey F; Diederichs K; Pos KM
    Science; 2006 Sep; 313(5791):1295-8. PubMed ID: 16946072
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB.
    Reading E; Ahdash Z; Fais C; Ricci V; Wang-Kan X; Grimsey E; Stone J; Malloci G; Lau AM; Findlay H; Konijnenberg A; Booth PJ; Ruggerone P; Vargiu AV; Piddock LJV; Politis A
    Nat Commun; 2020 Nov; 11(1):5565. PubMed ID: 33149158
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.