These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 21707057)

  • 1. Structure and mechanism of the trans-acting acyltransferase from the disorazole synthase.
    Wong FT; Jin X; Mathews II; Cane DE; Khosla C
    Biochemistry; 2011 Aug; 50(30):6539-48. PubMed ID: 21707057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.
    Miyanaga A; Ouchi R; Ishikawa F; Goto E; Tanabe G; Kudo F; Eguchi T
    J Am Chem Soc; 2018 Jun; 140(25):7970-7978. PubMed ID: 29870659
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conserved secondary structure in the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2) and the fatty acid synthase acyl carrier protein from Escherichia coli.
    Crump MP; Crosby J; Dempsey CE; Murray M; Hopwood DA; Simpson TJ
    FEBS Lett; 1996 Aug; 391(3):302-6. PubMed ID: 8764994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.
    Wong FT; Chen AY; Cane DE; Khosla C
    Biochemistry; 2010 Jan; 49(1):95-102. PubMed ID: 19921859
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D; Katsuyama Y; Horiuchi M; Fushinobu S; Chen A; Davis TD; Burkart MD; Ohnishi Y
    Nat Chem Biol; 2020 Jul; 16(7):776-782. PubMed ID: 32367018
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site.
    Szafranska AE; Hitchman TS; Cox RJ; Crosby J; Simpson TJ
    Biochemistry; 2002 Feb; 41(5):1421-7. PubMed ID: 11814333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ; Szafranska AE; Long J; Mills J; Cox RJ; Findlow SC; Simpson TJ; Crump MP; Crosby J
    Chem Biol; 2006 Jun; 13(6):587-96. PubMed ID: 16793516
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).
    Crump MP; Crosby J; Dempsey CE; Parkinson JA; Murray M; Hopwood DA; Simpson TJ
    Biochemistry; 1997 May; 36(20):6000-8. PubMed ID: 9166770
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Liou GF; Lau J; Cane DE; Khosla C
    Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mapping a ketosynthase:acyl carrier protein binding interface via unnatural amino acid-mediated photo-cross-linking.
    Ye Z; Williams GJ
    Biochemistry; 2014 Dec; 53(48):7494-502. PubMed ID: 25427130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The type I rat fatty acid synthase ACP shows structural homology and analogous biochemical properties to type II ACPs.
    Reed MA; Schweizer M; Szafranska AE; Arthur C; Nicholson TP; Cox RJ; Crosby J; Crump MP; Simpson TJ
    Org Biomol Chem; 2003 Feb; 1(3):463-71. PubMed ID: 12926246
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate.
    Park H; Kevany BM; Dyer DH; Thomas MG; Forest KT
    PLoS One; 2014; 9(10):e110965. PubMed ID: 25340352
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
    Kremer L; Nampoothiri KM; Lesjean S; Dover LG; Graham S; Betts J; Brennan PJ; Minnikin DE; Locht C; Besra GS
    J Biol Chem; 2001 Jul; 276(30):27967-74. PubMed ID: 11373295
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.
    Miyanaga A; Iwasawa S; Shinohara Y; Kudo F; Eguchi T
    Proc Natl Acad Sci U S A; 2016 Feb; 113(7):1802-7. PubMed ID: 26831085
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis of Transient Interactions of Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase.
    Miyanaga A; Kawada K; Chisuga T; Kudo F; Eguchi T
    Biochemistry; 2023 Jan; 62(1):17-21. PubMed ID: 36512613
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.
    Evans SE; Williams C; Arthur CJ; Burston SG; Simpson TJ; Crosby J; Crump MP
    Chembiochem; 2008 Oct; 9(15):2424-32. PubMed ID: 18770515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
    Feng Y; Zhang F; Huang S; Deng Z; Bai L; Zheng J
    Acta Crystallogr D Struct Biol; 2022 Jun; 78(Pt 6):779-791. PubMed ID: 35647924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P; Koppisch AT; Cane DE; Khosla C
    J Am Chem Soc; 2003 Nov; 125(47):14307-12. PubMed ID: 14624579
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.