BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 21707071)

  • 1. Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.
    Shawahna R; Uchida Y; Declèves X; Ohtsuki S; Yousif S; Dauchy S; Jacob A; Chassoux F; Daumas-Duport C; Couraud PO; Terasaki T; Scherrmann JM
    Mol Pharm; 2011 Aug; 8(4):1332-41. PubMed ID: 21707071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.
    Dauchy S; Dutheil F; Weaver RJ; Chassoux F; Daumas-Duport C; Couraud PO; Scherrmann JM; De Waziers I; Declèves X
    J Neurochem; 2008 Dec; 107(6):1518-28. PubMed ID: 19094056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.
    Roberts LM; Black DS; Raman C; Woodford K; Zhou M; Haggerty JE; Yan AT; Cwirla SE; Grindstaff KK
    Neuroscience; 2008 Aug; 155(2):423-38. PubMed ID: 18619525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.
    Nagasaka Y; Oda K; Iwatsubo T; Kawamura A; Usui T
    Biopharm Drug Dispos; 2012 Sep; 33(6):304-15. PubMed ID: 22847220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.
    Durmus S; Xu N; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Pharmacol Res; 2013 Oct; 76():9-16. PubMed ID: 23827160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inner Blood-Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig.
    Zhang Z; Uchida Y; Hirano S; Ando D; Kubo Y; Auriola S; Akanuma SI; Hosoya KI; Urtti A; Terasaki T; Tachikawa M
    Mol Pharm; 2017 Nov; 14(11):3729-3738. PubMed ID: 28954515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ontogeny of ABC and SLC transporters in the microvessels of developing rat brain.
    Soares RV; Do TM; Mabondzo A; Pons G; Chhun S
    Fundam Clin Pharmacol; 2016 Apr; 30(2):107-16. PubMed ID: 26662930
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology.
    Andersen V; Svenningsen K; Knudsen LA; Hansen AK; Holmskov U; Stensballe A; Vogel U
    World J Gastroenterol; 2015 Nov; 21(41):11862-76. PubMed ID: 26557010
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier.
    Do TM; Noel-Hudson MS; Ribes S; Besengez C; Smirnova M; Cisternino S; Buyse M; Calon F; Chimini G; Chacun H; Scherrmann JM; Farinotti R; Bourasset F
    J Alzheimers Dis; 2012; 30(1):155-66. PubMed ID: 22391220
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer.
    Chen M; Xue X; Wang F; An Y; Tang D; Xu Y; Wang H; Yuan Z; Gao W; Wei J; Zhang J; Miao Y
    Oncol Rep; 2012 Jan; 27(1):265-9. PubMed ID: 21956451
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATP-binding cassette transporters in primary central nervous system lymphoma: decreased expression of MDR1 P-glycoprotein and breast cancer resistance protein in tumor capillary endothelial cells.
    Sakata S; Fujiwara M; Ohtsuka K; Kamma H; Nagane M; Sakamoto A; Fujioka Y
    Oncol Rep; 2011 Feb; 25(2):333-9. PubMed ID: 21165575
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new intestinal cell culture model to discriminate the relative contribution of P-gp and BCRP on transport of substrates such as imatinib.
    Graber-Maier A; Gutmann H; Drewe J
    Mol Pharm; 2010 Oct; 7(5):1618-28. PubMed ID: 20701289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ABC efflux transporters in brain vasculature of Alzheimer's subjects.
    Wijesuriya HC; Bullock JY; Faull RL; Hladky SB; Barrand MA
    Brain Res; 2010 Oct; 1358():228-38. PubMed ID: 20727860
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation.
    Yousif S; Chaves C; Potin S; Margaill I; Scherrmann JM; Declèves X
    J Neurochem; 2012 Nov; 123(4):491-503. PubMed ID: 22845665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactions of tenofovir and tenofovir disoproxil fumarate with drug efflux transporters ABCB1, ABCG2, and ABCC2; role in transport across the placenta.
    Neumanova Z; Cerveny L; Ceckova M; Staud F
    AIDS; 2014 Jan; 28(1):9-17. PubMed ID: 24413260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier.
    Decleves X; Jacob A; Yousif S; Shawahna R; Potin S; Scherrmann JM
    Curr Drug Metab; 2011 Oct; 12(8):732-41. PubMed ID: 21623707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
    Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
    Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells.
    Svirnovski AI; Shman TV; Serhiyenka TF; Savitski VP; Smolnikova VV; Fedasenka UU
    Hematology; 2009 Aug; 14(4):204-12. PubMed ID: 19635183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance.
    Shi Z; Peng XX; Kim IW; Shukla S; Si QS; Robey RW; Bates SE; Shen T; Ashby CR; Fu LW; Ambudkar SV; Chen ZS
    Cancer Res; 2007 Nov; 67(22):11012-20. PubMed ID: 18006847
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
    Tang SC; Nguyen LN; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Int J Cancer; 2014 Mar; 134(6):1484-94. PubMed ID: 24037730
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.