These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 21707788)

  • 1. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells.
    Barbosa AD; Osório H; Sims KJ; Almeida T; Alves M; Bielawski J; Amorim MA; Moradas-Ferreira P; Hannun YA; Costa V
    Mol Microbiol; 2011 Jul; 81(2):515-27. PubMed ID: 21707788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells.
    Teixeira V; Medeiros TC; Vilaça R; Pereira AT; Chaves SR; Côrte-Real M; Moradas-Ferreira P; Costa V
    Cell Signal; 2015 Sep; 27(9):1840-9. PubMed ID: 26079297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging.
    Barbosa AD; Graça J; Mendes V; Chaves SR; Amorim MA; Mendes MV; Moradas-Ferreira P; Côrte-Real M; Costa V
    Mech Ageing Dev; 2012 May; 133(5):317-30. PubMed ID: 22445853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation.
    Barbosa AD; Pereira C; Osório H; Moradas-Ferreira P; Costa V
    Cell Cycle; 2016 Jun; 15(12):1620-30. PubMed ID: 27163342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis.
    Almeida T; Marques M; Mojzita D; Amorim MA; Silva RD; Almeida B; Rodrigues P; Ludovico P; Hohmann S; Moradas-Ferreira P; Côrte-Real M; Costa V
    Mol Biol Cell; 2008 Mar; 19(3):865-76. PubMed ID: 18162582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells.
    Teixeira V; Medeiros TC; Vilaça R; Moradas-Ferreira P; Costa V
    Microb Cell; 2014 Jan; 1(1):21-36. PubMed ID: 28357207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1.
    Vilaça R; Barros I; Matmati N; Silva E; Martins T; Teixeira V; Hannun YA; Costa V
    Biochim Biophys Acta Mol Basis Dis; 2018 Jan; 1864(1):79-88. PubMed ID: 28988886
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells.
    Teixeira V; Medeiros TC; Vilaça R; Ferreira J; Moradas-Ferreira P; Costa V
    Biochim Biophys Acta; 2016 Jan; 1861(1):21-33. PubMed ID: 26477382
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae.
    Cowart LA; Okamoto Y; Lu X; Hannun YA
    Biochem J; 2006 Feb; 393(Pt 3):733-40. PubMed ID: 16201964
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isc1 regulates sphingolipid metabolism in yeast mitochondria.
    Kitagaki H; Cowart LA; Matmati N; Vaena de Avalos S; Novgorodov SA; Zeidan YH; Bielawski J; Obeid LM; Hannun YA
    Biochim Biophys Acta; 2007 Nov; 1768(11):2849-61. PubMed ID: 17880915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism.
    Rego A; Costa M; Chaves SR; Matmati N; Pereira H; Sousa MJ; Moradas-Ferreira P; Hannun YA; Costa V; Côrte-Real M
    PLoS One; 2012; 7(11):e48571. PubMed ID: 23226203
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel Sit4 phosphatase complex is involved in the response to ceramide stress in yeast.
    Woodacre A; Lone MA; Jablonowski D; Schneiter R; Giorgini F; Schaffrath R
    Oxid Med Cell Longev; 2013; 2013():129645. PubMed ID: 24082981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.
    Vilaça R; Silva E; Nadais A; Teixeira V; Matmati N; Gaifem J; Hannun YA; Sá Miranda MC; Costa V
    Mol Microbiol; 2014 Feb; 91(3):438-51. PubMed ID: 24286211
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast.
    Matmati N; Metelli A; Tripathi K; Yan S; Mohanty BK; Hannun YA
    J Biol Chem; 2013 Jun; 288(24):17272-84. PubMed ID: 23620586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sphingolipids and mitochondrial function in budding yeast.
    Spincemaille P; Matmati N; Hannun YA; Cammue BP; Thevissen K
    Biochim Biophys Acta; 2014 Oct; 1840(10):3131-7. PubMed ID: 24973565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of SNF1/AMPK mediates the mitochondrial derepression, resistance to oxidative stress and increased lifespan of cells lacking the phosphatase Sit4p.
    Pereira C; Pereira AT; Costa V
    Biochim Biophys Acta Mol Cell Res; 2020 Apr; 1867(4):118660. PubMed ID: 31991152
    [No Abstract]   [Full Text] [Related]  

  • 17. Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria.
    Rego A; Cooper KF; Snider J; Hannun YA; Costa V; Côrte-Real M; Chaves SR
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Jun; 1863(6):576-583. PubMed ID: 29496584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sit4 Genetically Interacts with Vps27 to Regulate Mitochondrial Function and Lifespan in
    Martins TS; Correia M; Pinheiro D; Lemos C; Mendes MV; Pereira C; Costa V
    Cells; 2024 Apr; 13(8):. PubMed ID: 38667270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The serine/threonine protein phosphatase Sit4p activates multidrug resistance in Saccharomyces cerevisiae.
    Miranda MN; Masuda CA; Ferreira-Pereira A; Carvajal E; Ghislain M; Montero-Lomelí M
    FEMS Yeast Res; 2010 Sep; 10(6):674-86. PubMed ID: 20608983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae.
    Kitagaki H; Cowart LA; Matmati N; Montefusco D; Gandy J; de Avalos SV; Novgorodov SA; Zheng J; Obeid LM; Hannun YA
    J Biol Chem; 2009 Apr; 284(16):10818-30. PubMed ID: 19179331
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.