BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 21709232)

  • 1. Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes.
    Shin JW; Swift J; Spinler KR; Discher DE
    Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11458-63. PubMed ID: 21709232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.
    Chen Y; Boukour S; Milloud R; Favier R; Saposnik B; Schlegel N; Nurden A; Raslova H; Vainchenker W; Balland M; Nurden P; Debili N
    J Thromb Haemost; 2013 Dec; 11(12):2163-75. PubMed ID: 24165359
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
    Geue S; Aurbach K; Manke MC; Manukjan G; Münzer P; Stegner D; Brähler C; Walker-Allgaier B; Märklin M; Borst CE; Quintanilla-Fend L; Rath D; Geisler T; Salih HR; Seizer P; Lang F; Nieswandt B; Gawaz M; Schulze H; Pleines I; Borst O
    Blood; 2019 Nov; 134(21):1847-1858. PubMed ID: 31578203
    [TBL] [Abstract][Full Text] [Related]  

  • 4. OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets.
    Matsubara Y; Ono Y; Suzuki H; Arai F; Suda T; Murata M; Ikeda Y
    PLoS One; 2013; 8(3):e58123. PubMed ID: 23469264
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation.
    Aguilar A; Pertuy F; Eckly A; Strassel C; Collin D; Gachet C; Lanza F; Léon C
    Blood; 2016 Oct; 128(16):2022-2032. PubMed ID: 27503502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.
    Chen Z; Naveiras O; Balduini A; Mammoto A; Conti MA; Adelstein RS; Ingber D; Daley GQ; Shivdasani RA
    Blood; 2007 Jul; 110(1):171-9. PubMed ID: 17392504
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ibrutinib Suppresses Early Megakaryopoiesis but Enhances Proplatelet Formation.
    Huang J; Huang S; Ma Z; Lin X; Li X; Huang X; Wang J; Ye W; Li Y; He D; Yang M; Pan J; Ling Q; Li F; Mao S; Wang H; Wang Y; Jin J
    Thromb Haemost; 2021 Feb; 121(2):192-205. PubMed ID: 32961571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice.
    Eckly A; Rinckel JY; Laeuffer P; Cazenave JP; Lanza F; Gachet C; Léon C
    J Thromb Haemost; 2010 Oct; 8(10):2243-51. PubMed ID: 20695978
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production.
    Panuganti S; Schlinker AC; Lindholm PF; Papoutsakis ET; Miller WM
    Tissue Eng Part A; 2013 Apr; 19(7-8):998-1014. PubMed ID: 23190353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.
    Mazharian A; Thomas SG; Dhanjal TS; Buckley CD; Watson SP
    Blood; 2010 Aug; 116(5):793-800. PubMed ID: 20457868
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new path to platelet production through matrix sensing.
    Abbonante V; Di Buduo CA; Gruppi C; De Maria C; Spedden E; De Acutis A; Staii C; Raspanti M; Vozzi G; Kaplan DL; Moccia F; Ravid K; Balduini A
    Haematologica; 2017 Jul; 102(7):1150-1160. PubMed ID: 28411253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.
    Machlus KR; Wu SK; Stumpo DJ; Soussou TS; Paul DS; Campbell RA; Kalwa H; Michel T; Bergmeier W; Weyrich AS; Blackshear PJ; Hartwig JH; Italiano JE
    Blood; 2016 Mar; 127(11):1468-80. PubMed ID: 26744461
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.
    Eckly A; Strassel C; Freund M; Cazenave JP; Lanza F; Gachet C; Léon C
    Blood; 2009 Apr; 113(14):3182-9. PubMed ID: 18984861
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The critical role of myosin IIA in platelet internal contraction.
    Johnson GJ; Leis LA; Krumwiede MD; White JG
    J Thromb Haemost; 2007 Jul; 5(7):1516-29. PubMed ID: 17488351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anagrelide platelet-lowering effect is due to inhibition of both megakaryocyte maturation and proplatelet formation: insight into potential mechanisms.
    Espasandin YR; Glembotsky AC; Grodzielski M; Lev PR; Goette NP; Molinas FC; Marta RF; Heller PG
    J Thromb Haemost; 2015 Apr; 13(4):631-42. PubMed ID: 25604267
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes.
    Balduini A; Pallotta I; Malara A; Lova P; Pecci A; Viarengo G; Balduini CL; Torti M
    J Thromb Haemost; 2008 Nov; 6(11):1900-7. PubMed ID: 18752571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly.
    Jurak Begonja A; Hoffmeister KM; Hartwig JH; Falet H
    Blood; 2011 Aug; 118(8):2285-95. PubMed ID: 21652675
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SET domain containing 2 promotes megakaryocyte polyploidization and platelet generation through methylation of α-tubulin.
    Chen L; Liu J; Chen K; Su Y; Chen Y; Lei Y; Si J; Zhang J; Zhang Z; Zou W; Zhang X; Rondina MT; Wang QF; Li Y
    J Thromb Haemost; 2024 Jun; 22(6):1727-1741. PubMed ID: 38537781
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Long-term platelet production assessed in NOD/SCID mice injected with cord blood CD34+ cells, thrombopoietin-amplified in clinical grade serum-free culture.
    Mattia G; Milazzo L; Vulcano F; Pascuccio M; Macioce G; Hassan HJ; Giampaolo A
    Exp Hematol; 2008 Feb; 36(2):244-52. PubMed ID: 18023520
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets.
    Pertuy F; Eckly A; Weber J; Proamer F; Rinckel JY; Lanza F; Gachet C; Léon C
    Blood; 2014 Feb; 123(8):1261-9. PubMed ID: 24243973
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.