BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 21711053)

  • 1. Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?
    Van Goethem S; Matheeussen V; Joossens J; Lambeir AM; Chen X; De Meester I; Haemers A; Augustyns K; Van der Veken P
    J Med Chem; 2011 Aug; 54(16):5737-46. PubMed ID: 21711053
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors.
    Van Goethem S; Van der Veken P; Dubois V; Soroka A; Lambeir AM; Chen X; Haemers A; Scharpé S; De Meester I; Augustyns K
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4159-62. PubMed ID: 18556198
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads.
    Van der Veken P; De Meester I; Dubois V; Soroka A; Van Goethem S; Maes MB; Brandt I; Lambeir AM; Chen X; Haemers A; Scharpé S; Augustyns K
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4154-8. PubMed ID: 18556199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Docking-based 3D-QSAR study for selectivity of DPP4, DPP8, and DPP9 inhibitors.
    Kang NS; Ahn JH; Kim SS; Chae CH; Yoo SE
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3716-21. PubMed ID: 17462890
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors.
    Huan Y; Jiang Q; Liu JL; Shen ZF
    J Pharmacol Toxicol Methods; 2015; 71():8-12. PubMed ID: 25464020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.
    Lu IL; Lee SJ; Tsu H; Wu SY; Kao KH; Chien CH; Chang YY; Chen YS; Cheng JH; Chang CN; Chen TW; Chang SP; Chen X; Jiaang WT
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3271-5. PubMed ID: 15927466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dipeptidyl peptidase 8/9-like activity in human leukocytes.
    Maes MB; Dubois V; Brandt I; Lambeir AM; Van der Veken P; Augustyns K; Cheng JD; Chen X; Scharpé S; De Meester I
    J Leukoc Biol; 2007 May; 81(5):1252-7. PubMed ID: 17287297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV.
    Tsu H; Chen X; Chen CT; Lee SJ; Chang CN; Kao KH; Coumar MS; Yeh YT; Chien CH; Wang HS; Lin KT; Chang YY; Wu SH; Chen YS; Lu IL; Wu SY; Tsai TY; Chen WC; Hsieh HP; Chao YS; Jiaang WT
    J Med Chem; 2006 Jan; 49(1):373-80. PubMed ID: 16392822
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates.
    Van der Veken P; Soroka A; Brandt I; Chen YS; Maes MB; Lambeir AM; Chen X; Haemers A; Scharpé S; Augustyns K; De Meester I
    J Med Chem; 2007 Nov; 50(23):5568-70. PubMed ID: 17958345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9.
    Pilla E; Kilisch M; Lenz C; Urlaub H; Geiss-Friedlander R
    J Biol Chem; 2013 Nov; 288(45):32787-32796. PubMed ID: 24072711
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
    Lankas GR; Leiting B; Roy RS; Eiermann GJ; Beconi MG; Biftu T; Chan CC; Edmondson S; Feeney WP; He H; Ippolito DE; Kim D; Lyons KA; Ok HO; Patel RA; Petrov AN; Pryor KA; Qian X; Reigle L; Woods A; Wu JK; Zaller D; Zhang X; Zhu L; Weber AE; Thornberry NA
    Diabetes; 2005 Oct; 54(10):2988-94. PubMed ID: 16186403
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor.
    Wu JJ; Tang HK; Yeh TK; Chen CM; Shy HS; Chu YR; Chien CH; Tsai TY; Huang YC; Huang YL; Huang CH; Tseng HY; Jiaang WT; Chao YS; Chen X
    Biochem Pharmacol; 2009 Jul; 78(2):203-10. PubMed ID: 19439267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein.
    Tsai TY; Yeh TK; Chen X; Hsu T; Jao YC; Huang CH; Song JS; Huang YC; Chien CH; Chiu JH; Yen SC; Tang HK; Chao YS; Jiaang WT
    J Med Chem; 2010 Sep; 53(18):6572-83. PubMed ID: 20718420
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9-Specific Lead.
    Benramdane S; De Loose J; Beyens O; Van Rymenant Y; Vliegen G; Augustyns K; De Winter H; De Meester I; Van der Veken P
    ChemMedChem; 2022 Aug; 17(15):e202200097. PubMed ID: 35760756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
    Matheeussen V; Waumans Y; Martinet W; Van Goethem S; Van der Veken P; Scharpé S; Augustyns K; De Meyer GR; De Meester I
    Basic Res Cardiol; 2013 May; 108(3):350. PubMed ID: 23608773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.
    Jiaang WT; Chen YS; Hsu T; Wu SH; Chien CH; Chang CN; Chang SP; Lee SJ; Chen X
    Bioorg Med Chem Lett; 2005 Feb; 15(3):687-91. PubMed ID: 15664838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues.
    Harstad EB; Rosenblum JS; Gorrell MD; Achanzar WE; Minimo L; Wu J; Rosini-Marthaler L; Gullo R; Ordway ND; Kirby MS; Chadwick KD; Cosma GN; Moyer CF
    Regul Pept; 2013 Sep; 186():26-35. PubMed ID: 23850796
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells.
    Zhang Y; Li K; Li Y; Zhao W; Wang L; Chen Z; Ma X; Yao T; Wang J; Dong W; Li X; Tian X; Fu R
    Pharmacol Res; 2021 Jul; 169():105630. PubMed ID: 33932609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An example of designed multiple ligands spanning protein classes: dual MCH-1R antagonists/DPPIV inhibitors.
    Gattrell WT; Sambrook Smith CP; Smith AJ
    Bioorg Med Chem Lett; 2012 Apr; 22(7):2464-9. PubMed ID: 22377519
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
    Ross B; Krapp S; Augustin M; Kierfersauer R; Arciniega M; Geiss-Friedlander R; Huber R
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):E1437-E1445. PubMed ID: 29382749
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.