336 related articles for article (PubMed ID: 21718164)
1. Hypoxia: adapting to high altitude by mutating EPAS-1, the gene encoding HIF-2α.
van Patot MC; Gassmann M
High Alt Med Biol; 2011; 12(2):157-67. PubMed ID: 21718164
[TBL] [Abstract][Full Text] [Related]
2. Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia.
Petousi N; Croft QP; Cavalleri GL; Cheng HY; Formenti F; Ishida K; Lunn D; McCormack M; Shianna KV; Talbot NP; Ratcliffe PJ; Robbins PA
J Appl Physiol (1985); 2014 Apr; 116(7):893-904. PubMed ID: 24030663
[TBL] [Abstract][Full Text] [Related]
3. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders.
Tashi T; Scott Reading N; Wuren T; Zhang X; Moore LG; Hu H; Tang F; Shestakova A; Lorenzo F; Burjanivova T; Koul P; Guchhait P; Wittwer CT; Julian CG; Shah B; Huff CD; Gordeuk VR; Prchal JT; Ge R
J Mol Med (Berl); 2017 Jun; 95(6):665-670. PubMed ID: 28233034
[TBL] [Abstract][Full Text] [Related]
4. Genetic and immune changes in Tibetan high-altitude populations contribute to biological adaptation to hypoxia.
Bai J; Li L; Li Y; Zhang L
Environ Health Prev Med; 2022; 27():39. PubMed ID: 36244759
[TBL] [Abstract][Full Text] [Related]
5. EPAS 1, congenital heart disease, and high altitude: disclosures by genetics, bioinformatics, and experimental embryology.
Sergi C
Biosci Rep; 2019 May; 39(5):. PubMed ID: 31015364
[TBL] [Abstract][Full Text] [Related]
6. Genetic adaptation of the hypoxia-inducible factor pathway to oxygen pressure among eurasian human populations.
Ji LD; Qiu YQ; Xu J; Irwin DM; Tam SC; Tang NL; Zhang YP
Mol Biol Evol; 2012 Nov; 29(11):3359-70. PubMed ID: 22628534
[TBL] [Abstract][Full Text] [Related]
7. 'ome on the Range: altitude adaptation, positive selection, and Himalayan genomics.
MacInnis MJ; Rupert JL
High Alt Med Biol; 2011; 12(2):133-9. PubMed ID: 21718161
[TBL] [Abstract][Full Text] [Related]
8. Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
Peng Y; Cui C; He Y; Ouzhuluobu ; Zhang H; Yang D; Zhang Q; Bianbazhuoma ; Yang L; He Y; Xiang K; Zhang X; Bhandari S; Shi P; Yangla ; Dejiquzong ; Baimakangzhuo ; Duojizhuoma ; Pan Y; Cirenyangji ; Baimayangji ; Gonggalanzi ; Bai C; Bianba ; Basang ; Ciwangsangbu ; Xu S; Chen H; Liu S; Wu T; Qi X; Su B
Mol Biol Evol; 2017 Apr; 34(4):818-830. PubMed ID: 28096303
[TBL] [Abstract][Full Text] [Related]
9. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells.
Warnecke C; Zaborowska Z; Kurreck J; Erdmann VA; Frei U; Wiesener M; Eckardt KU
FASEB J; 2004 Sep; 18(12):1462-4. PubMed ID: 15240563
[TBL] [Abstract][Full Text] [Related]
10. Regulation of erythropoiesis by hypoxia-inducible factors.
Haase VH
Blood Rev; 2013 Jan; 27(1):41-53. PubMed ID: 23291219
[TBL] [Abstract][Full Text] [Related]
11. Yak response to high-altitude hypoxic stress by altering mRNA expression and DNA methylation of hypoxia-inducible factors.
Xiong X; Fu M; Lan D; Li J; Zi X; Zhong J
Anim Biotechnol; 2015; 26(3):222-9. PubMed ID: 25927169
[TBL] [Abstract][Full Text] [Related]
12. Identification of key HIF-1α target genes that regulate adaptation to hypoxic conditions in Tibetan chicken embryos.
Zhang Y; Zhang H; Zhang B; Ling Y; Zhang H
Gene; 2020 Mar; 729():144321. PubMed ID: 31887331
[TBL] [Abstract][Full Text] [Related]
13. [Serum levels and significance of HIF-1α and HIF-2α in healthy Tibetan and Han residents at different altitudes].
Guan W; Li X; Yang YZ; Wang J; Feng XY; Xu JH
Zhonghua Yi Xue Za Zhi; 2013 Oct; 93(38):3057-9. PubMed ID: 24417928
[TBL] [Abstract][Full Text] [Related]
14. Fine tuning the HIF-1 'global' O2 sensor for hypobaric hypoxia in Andean high-altitude natives.
Hochachka PW; Rupert JL
Bioessays; 2003 May; 25(5):515-9. PubMed ID: 12717822
[TBL] [Abstract][Full Text] [Related]
15. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.
Chavez JC; Baranova O; Lin J; Pichiule P
J Neurosci; 2006 Sep; 26(37):9471-81. PubMed ID: 16971531
[TBL] [Abstract][Full Text] [Related]
16. Human high-altitude adaptation: forward genetics meets the HIF pathway.
Bigham AW; Lee FS
Genes Dev; 2014 Oct; 28(20):2189-204. PubMed ID: 25319824
[TBL] [Abstract][Full Text] [Related]
17. Regulation of erythropoietin production.
Eckardt KU; Kurtz A
Eur J Clin Invest; 2005 Dec; 35 Suppl 3():13-9. PubMed ID: 16281953
[TBL] [Abstract][Full Text] [Related]
18. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
Weidemann A; Kerdiles YM; Knaup KX; Rafie CA; Boutin AT; Stockmann C; Takeda N; Scadeng M; Shih AY; Haase VH; Simon MC; Kleinfeld D; Johnson RS
J Clin Invest; 2009 Nov; 119(11):3373-83. PubMed ID: 19809162
[TBL] [Abstract][Full Text] [Related]
19. [Adaptation to high altitudes: on which genes was selective pressure exercised?].
Labie D
Med Sci (Paris); 2010 Dec; 26(12):1038-9. PubMed ID: 21187040
[No Abstract] [Full Text] [Related]
20. Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation.
Tan Q; Kerestes H; Percy MJ; Pietrofesa R; Chen L; Khurana TS; Christofidou-Solomidou M; Lappin TR; Lee FS
J Biol Chem; 2013 Jun; 288(24):17134-44. PubMed ID: 23640890
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]