These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 21718246)

  • 1. New insights in drug-induced mitochondrial toxicity.
    Nadanaciva S; Will Y
    Curr Pharm Des; 2011; 17(20):2100-12. PubMed ID: 21718246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigating mitochondrial dysfunction to increase drug safety in the pharmaceutical industry.
    Nadanaciva S; Will Y
    Curr Drug Targets; 2011 Jun; 12(6):774-82. PubMed ID: 21275886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?
    Pereira SP; Pereira GC; Moreno AJ; Oliveira PJ
    Altern Lab Anim; 2009 Sep; 37(4):355-65. PubMed ID: 19807208
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of mitochondrial dysfunction and drug safety.
    Nadanaciva S; Will Y
    IDrugs; 2009 Nov; 12(11):706-10. PubMed ID: 19844857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The use of high-throughput screening techniques to evaluate mitochondrial toxicity.
    Wills LP
    Toxicology; 2017 Nov; 391():34-41. PubMed ID: 28789971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple Targets for Drug-Induced Mitochondrial Toxicity.
    Wallace KB
    Curr Med Chem; 2015; 22(20):2488-92. PubMed ID: 25973981
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death.
    Swiss R; Niles A; Cali JJ; Nadanaciva S; Will Y
    Toxicol In Vitro; 2013 Sep; 27(6):1789-97. PubMed ID: 23726864
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial toxicity assessment in industry--a decade of technology development and insight.
    Will Y; Dykens J
    Expert Opin Drug Metab Toxicol; 2014 Aug; 10(8):1061-7. PubMed ID: 25023361
    [No Abstract]   [Full Text] [Related]  

  • 9. The significance of mitochondrial toxicity testing in drug development.
    Dykens JA; Will Y
    Drug Discov Today; 2007 Sep; 12(17-18):777-85. PubMed ID: 17826691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A high content screening assay to predict human drug-induced liver injury during drug discovery.
    Persson M; Løye AF; Mow T; Hornberg JJ
    J Pharmacol Toxicol Methods; 2013; 68(3):302-13. PubMed ID: 23933113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Current concepts in drug-induced mitochondrial toxicity.
    Nadanaciva S; Will Y
    Curr Protoc Toxicol; 2009 May; Chapter 2():Unit 2.15. PubMed ID: 20941696
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug induced mitochondrial dysfunction: Mechanisms and adverse clinical consequences.
    Vuda M; Kamath A
    Mitochondrion; 2016 Nov; 31():63-74. PubMed ID: 27771494
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug-associated mitochondrial toxicity and its detection.
    Amacher DE
    Curr Med Chem; 2005; 12(16):1829-39. PubMed ID: 16101504
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The acute extracellular flux (XF) assay to assess compound effects on mitochondrial function.
    Wang R; Novick SJ; Mangum JB; Queen K; Ferrick DA; Rogers GW; Stimmel JB
    J Biomol Screen; 2015 Mar; 20(3):422-9. PubMed ID: 25381255
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity.
    Hoogstraten CA; Lyon JJ; Smeitink JAM; Russel FGM; Schirris TJJ
    Pharmacol Rev; 2023 May; 75(3):463-486. PubMed ID: 36627212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays.
    Hynes J; Nadanaciva S; Swiss R; Carey C; Kirwan S; Will Y
    Toxicol In Vitro; 2013 Mar; 27(2):560-9. PubMed ID: 23147640
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Translating extracellular microRNA into clinical biomarkers for drug-induced toxicity: from high-throughput profiling to validation.
    Wang W; Shi Q; Mattes WB; Mendrick DL; Yang X
    Biomark Med; 2015; 9(11):1177-88. PubMed ID: 26501984
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human-Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in Humans.
    Goda K; Kobayashi A; Takahashi A; Takahashi T; Saito K; Maekawa K; Saito Y; Sugai S
    Int J Mol Sci; 2017 Apr; 18(4):. PubMed ID: 28417920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety?
    Pereira CV; Moreira AC; Pereira SP; Machado NG; Carvalho FS; Sardão VA; Oliveira PJ
    Curr Drug Saf; 2009 Jan; 4(1):34-54. PubMed ID: 19149524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predicting in vivo safety characteristics using physiochemical properties and in vitro assays.
    Greene N; Song M
    Future Med Chem; 2011 Sep; 3(12):1503-11. PubMed ID: 21882943
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.