201 related articles for article (PubMed ID: 21718295)
1. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease.
Abuznait AH; Cain C; Ingram D; Burk D; Kaddoumi A
J Pharm Pharmacol; 2011 Aug; 63(8):1111-8. PubMed ID: 21718295
[TBL] [Abstract][Full Text] [Related]
2. Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity.
Abuznait AH; Patrick SG; Kaddoumi A
J Pharm Pharm Sci; 2011; 14(2):236-48. PubMed ID: 21733412
[TBL] [Abstract][Full Text] [Related]
3. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease.
Qosa H; Abuznait AH; Hill RA; Kaddoumi A
J Alzheimers Dis; 2012; 31(1):151-65. PubMed ID: 22504320
[TBL] [Abstract][Full Text] [Related]
4. Proteasome inhibition protects blood-brain barrier P-glycoprotein and lowers Aβ brain levels in an Alzheimer's disease model.
Vulin M; Zhong Y; Maloney BJ; Bauer B; Hartz AMS
Fluids Barriers CNS; 2023 Oct; 20(1):70. PubMed ID: 37803468
[TBL] [Abstract][Full Text] [Related]
5. Lack of P-glycoprotein Results in Impairment of Removal of Beta-Amyloid and Increased Intraparenchymal Cerebral Amyloid Angiopathy after Active Immunization in a Transgenic Mouse Model of Alzheimer's Disease.
Bruckmann S; Brenn A; Grube M; Niedrig K; Holtfreter S; von Bohlen und Halbach O; Groschup M; Keller M; Vogelgesang S
Curr Alzheimer Res; 2017; 14(6):656-667. PubMed ID: 27915995
[TBL] [Abstract][Full Text] [Related]
6. MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.
Kuhnke D; Jedlitschky G; Grube M; Krohn M; Jucker M; Mosyagin I; Cascorbi I; Walker LC; Kroemer HK; Warzok RW; Vogelgesang S
Brain Pathol; 2007 Oct; 17(4):347-53. PubMed ID: 17610523
[TBL] [Abstract][Full Text] [Related]
7. Protecting P-glycoprotein at the blood-brain barrier from degradation in an Alzheimer's disease mouse model.
Ding Y; Zhong Y; Baldeshwiler A; Abner EL; Bauer B; Hartz AMS
Fluids Barriers CNS; 2021 Mar; 18(1):10. PubMed ID: 33676539
[TBL] [Abstract][Full Text] [Related]
8. New Evidence for P-gp-Mediated Export of Amyloid-β PEPTIDES in Molecular, Blood-Brain Barrier and Neuronal Models.
Chai AB; Hartz AMS; Gao X; Yang A; Callaghan R; Gelissen IC
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33383667
[TBL] [Abstract][Full Text] [Related]
9. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease.
Hartz AM; Miller DS; Bauer B
Mol Pharmacol; 2010 May; 77(5):715-23. PubMed ID: 20101004
[TBL] [Abstract][Full Text] [Related]
10. P-glycoprotein: a role in the export of amyloid-β in Alzheimer's disease?
Chai AB; Leung GKF; Callaghan R; Gelissen IC
FEBS J; 2020 Feb; 287(4):612-625. PubMed ID: 31750987
[TBL] [Abstract][Full Text] [Related]
11. Abundance of P-Glycoprotein and Other Drug Transporters at the Human Blood-Brain Barrier in Alzheimer's Disease: A Quantitative Targeted Proteomic Study.
Storelli F; Billington S; Kumar AR; Unadkat JD
Clin Pharmacol Ther; 2021 Mar; 109(3):667-675. PubMed ID: 32885413
[TBL] [Abstract][Full Text] [Related]
12. Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling.
Park R; Kook SY; Park JC; Mook-Jung I
Cell Death Dis; 2014 Jun; 5(6):e1299. PubMed ID: 24967961
[TBL] [Abstract][Full Text] [Related]
13. The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.
Vogelgesang S; Warzok RW; Cascorbi I; Kunert-Keil C; Schroeder E; Kroemer HK; Siegmund W; Walker LC; Pahnke J
Curr Alzheimer Res; 2004 May; 1(2):121-5. PubMed ID: 15975076
[TBL] [Abstract][Full Text] [Related]
14. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
Storck SE; Hartz AMS; Bernard J; Wolf A; Kachlmeier A; Mahringer A; Weggen S; Pahnke J; Pietrzik CU
Brain Behav Immun; 2018 Oct; 73():21-33. PubMed ID: 30041013
[TBL] [Abstract][Full Text] [Related]
15. beta-Amyloid efflux mediated by p-glycoprotein.
Lam FC; Liu R; Lu P; Shapiro AB; Renoir JM; Sharom FJ; Reiner PB
J Neurochem; 2001 Feb; 76(4):1121-8. PubMed ID: 11181832
[TBL] [Abstract][Full Text] [Related]
16. Natural Products based P-glycoprotein Activators for Improved β-amyloid Clearance in Alzheimer's Disease: An in silico Approach.
Shinde P; Vidyasagar N; Dhulap S; Dhulap A; Hirwani R
Cent Nerv Syst Agents Med Chem; 2015; 16(1):50-9. PubMed ID: 26306632
[TBL] [Abstract][Full Text] [Related]
17. Role of P-glycoprotein in mediating rivastigmine effect on amyloid-β brain load and related pathology in Alzheimer's disease mouse model.
Mohamed LA; Keller JN; Kaddoumi A
Biochim Biophys Acta; 2016 Apr; 1862(4):778-787. PubMed ID: 26780497
[TBL] [Abstract][Full Text] [Related]
18. Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein.
McCormick JW; Ammerman L; Chen G; Vogel PD; Wise JG
PLoS One; 2021; 16(4):e0250371. PubMed ID: 33901197
[TBL] [Abstract][Full Text] [Related]
19. Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.
Vogelgesang S; Cascorbi I; Schroeder E; Pahnke J; Kroemer HK; Siegmund W; Kunert-Keil C; Walker LC; Warzok RW
Pharmacogenetics; 2002 Oct; 12(7):535-41. PubMed ID: 12360104
[TBL] [Abstract][Full Text] [Related]
20. Brain Microvascular Endothelial Cell Derived Exosomes Potently Ameliorate Cognitive Dysfunction by Enhancing the Clearance of Aβ Through Up-Regulation of P-gp in Mouse Model of AD.
Pan J; He R; Huo Q; Shi Y; Zhao L
Neurochem Res; 2020 Sep; 45(9):2161-2172. PubMed ID: 32583212
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
