BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

693 related articles for article (PubMed ID: 21724828)

  • 21. MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
    Bernt KM; Zhu N; Sinha AU; Vempati S; Faber J; Krivtsov AV; Feng Z; Punt N; Daigle A; Bullinger L; Pollock RM; Richon VM; Kung AL; Armstrong SA
    Cancer Cell; 2011 Jul; 20(1):66-78. PubMed ID: 21741597
    [TBL] [Abstract][Full Text] [Related]  

  • 22. DOT1L regulates dystrophin expression and is critical for cardiac function.
    Nguyen AT; Xiao B; Neppl RL; Kallin EM; Li J; Chen T; Wang DZ; Xiao X; Zhang Y
    Genes Dev; 2011 Feb; 25(3):263-74. PubMed ID: 21289070
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis.
    Yang L; Liu L; Gao H; Pinnamaneni JP; Sanagasetti D; Singh VP; Wang K; Mathison M; Zhang Q; Chen F; Mo Q; Rosengart T; Yang J
    J Hematol Oncol; 2017 Oct; 10(1):159. PubMed ID: 28974232
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
    Yang L; Lei Q; Li L; Yang J; Dong Z; Cui H
    Clin Epigenetics; 2019 Dec; 11(1):199. PubMed ID: 31888761
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
    Bovio PP; Franz H; Heidrich S; Rauleac T; Kilpert F; Manke T; Vogel T
    Mol Neurobiol; 2019 Jun; 56(6):4273-4287. PubMed ID: 30302725
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
    Feng Q; Wang H; Ng HH; Erdjument-Bromage H; Tempst P; Struhl K; Zhang Y
    Curr Biol; 2002 Jun; 12(12):1052-8. PubMed ID: 12123582
    [TBL] [Abstract][Full Text] [Related]  

  • 27. CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.
    Yu Z; Kong Q; Kone BC
    Am J Physiol Renal Physiol; 2010 Mar; 298(3):F617-24. PubMed ID: 20053791
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases.
    Wakeman TP; Wang Q; Feng J; Wang XF
    EMBO J; 2012 May; 31(9):2169-81. PubMed ID: 22373577
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.
    Wen L; Fu L; Guo X; Chen Y; Shi YB
    FASEB J; 2015 Feb; 29(2):385-93. PubMed ID: 25366346
    [TBL] [Abstract][Full Text] [Related]  

  • 30. DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
    Ho LL; Sinha A; Verzi M; Bernt KM; Armstrong SA; Shivdasani RA
    Mol Cell Biol; 2013 May; 33(9):1735-45. PubMed ID: 23428873
    [TBL] [Abstract][Full Text] [Related]  

  • 31. DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
    Nguyen AT; Taranova O; He J; Zhang Y
    Blood; 2011 Jun; 117(25):6912-22. PubMed ID: 21521783
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
    FitzGerald J; Moureau S; Drogaris P; O'Connell E; Abshiru N; Verreault A; Thibault P; Grenon M; Lowndes NF
    PLoS One; 2011 Feb; 6(2):e14714. PubMed ID: 21383990
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.
    Wysocki R; Javaheri A; Allard S; Sha F; Côté J; Kron SJ
    Mol Cell Biol; 2005 Oct; 25(19):8430-43. PubMed ID: 16166626
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
    Jo SY; Granowicz EM; Maillard I; Thomas D; Hess JL
    Blood; 2011 May; 117(18):4759-68. PubMed ID: 21398221
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Targeting the histone H3 lysine 79 methyltransferase DOT1L in MLL-rearranged leukemias.
    Yi Y; Ge S
    J Hematol Oncol; 2022 Mar; 15(1):35. PubMed ID: 35331314
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79.
    Tatum D; Li S
    J Biol Chem; 2011 May; 286(20):17530-5. PubMed ID: 21460225
    [TBL] [Abstract][Full Text] [Related]  

  • 37. [DOT1: a distinct class of histone lysine methyltransferase].
    Gao WL; Liu HL
    Yi Chuan; 2007 Dec; 29(12):1449-54. PubMed ID: 18065378
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia.
    Dafflon C; Craig VJ; Méreau H; Gräsel J; Schacher Engstler B; Hoffman G; Nigsch F; Gaulis S; Barys L; Ito M; Aguadé-Gorgorió J; Bornhauser B; Bourquin JP; Proske A; Stork-Fux C; Murakami M; Sellers WR; Hofmann F; Schwaller J; Tiedt R
    Leukemia; 2017 Jun; 31(6):1269-1277. PubMed ID: 27840424
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of the DOT1L network: implications of diverse roles for DOT1L.
    Park G; Gong Z; Chen J; Kim JE
    Protein J; 2010 Apr; 29(3):213-23. PubMed ID: 20431927
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
    Deshpande AJ; Chen L; Fazio M; Sinha AU; Bernt KM; Banka D; Dias S; Chang J; Olhava EJ; Daigle SR; Richon VM; Pollock RM; Armstrong SA
    Blood; 2013 Mar; 121(13):2533-41. PubMed ID: 23361907
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 35.