BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 21732699)

  • 1. Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds.
    Shimada T; Murayama N; Tanaka K; Takenaka S; Guengerich FP; Yamazaki H; Komori M
    Chem Res Toxicol; 2011 Aug; 24(8):1327-37. PubMed ID: 21732699
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.
    Shimada T; El-Bayoumy K; Upadhyaya P; Sutter TR; Guengerich FP; Yamazaki H
    Cancer Res; 1997 Nov; 57(21):4757-64. PubMed ID: 9354437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
    Shimada T; Guengerich FP
    Chem Res Toxicol; 2006 Feb; 19(2):288-94. PubMed ID: 16485905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.
    Shimada T; Tanaka K; Takenaka S; Murayama N; Martin MV; Foroozesh MK; Yamazaki H; Guengerich FP; Komori M
    Chem Res Toxicol; 2010 Dec; 23(12):1921-35. PubMed ID: 21053930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.
    Shimada T; Murayama N; Okada K; Funae Y; Yamazaki H; Guengerich FP
    Chem Res Toxicol; 2007 Mar; 20(3):489-96. PubMed ID: 17291012
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.
    Shimada T; Kim D; Murayama N; Tanaka K; Takenaka S; Nagy LD; Folkman LM; Foroozesh MK; Komori M; Yamazaki H; Guengerich FP
    Chem Res Toxicol; 2013 Apr; 26(4):517-28. PubMed ID: 23432429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.
    Shimada T
    Toxicol Res; 2017 Apr; 33(2):79-96. PubMed ID: 28443179
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.
    Shimada T; Takenaka S; Kakimoto K; Murayama N; Lim YR; Kim D; Foroozesh MK; Yamazaki H; Guengerich FP; Komori M
    Chem Res Toxicol; 2016 Jun; 29(6):1029-40. PubMed ID: 27137136
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.
    Shimada T; Murajama N; Tanaka K; Takenaka S; Imai Y; Hopkins NE; Foroozesh MK; Alworth WL; Yamazaki H; Guengerich FP; Komori M
    Chem Res Toxicol; 2008 Dec; 21(12):2313-23. PubMed ID: 19548353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.
    Shimada T; Murayama N; Yamazaki H; Tanaka K; Takenaka S; Komori M; Kim D; Guengerich FP
    Chem Res Toxicol; 2013 Apr; 26(4):529-37. PubMed ID: 23432465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
    Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
    Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.
    Shimada T; Inoue K; Suzuki Y; Kawai T; Azuma E; Nakajima T; Shindo M; Kurose K; Sugie A; Yamagishi Y; Fujii-Kuriyama Y; Hashimoto M
    Carcinogenesis; 2002 Jul; 23(7):1199-207. PubMed ID: 12117779
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.
    Shimada T; Murayama N; Kakimoto K; Takenaka S; Lim YR; Yeom S; Kim D; Yamazaki H; Guengerich FP; Komori M
    Xenobiotica; 2018 Jun; 48(6):565-575. PubMed ID: 28648140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13.
    Shimada T; Takenaka S; Murayama N; Kramlinger VM; Kim JH; Kim D; Liu J; Foroozesh MK; Yamazaki H; Guengerich FP; Komori M
    Xenobiotica; 2016; 46(3):211-24. PubMed ID: 26247835
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.
    Jerabek P; Martinek V; Stiborova M
    Neuro Endocrinol Lett; 2012; 33 Suppl 3():25-32. PubMed ID: 23353840
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers.
    von Weymarn LB; Chun JA; Hollenberg PF
    Carcinogenesis; 2006 Apr; 27(4):782-90. PubMed ID: 16364922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.
    Shimada T; Yamazaki H; Foroozesh M; Hopkins NE; Alworth WL; Guengerich FP
    Chem Res Toxicol; 1998 Sep; 11(9):1048-56. PubMed ID: 9760279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular Cloning, Tissue Distribution, and Functional Characterization of Marmoset Cytochrome P450 1A1, 1A2, and 1B1.
    Uehara S; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2016 Jan; 44(1):8-15. PubMed ID: 26502772
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.
    Takahashi E; Fujita K; Kamataki T; Arimoto-Kobayashi S; Okamoto K; Negishi T
    Mutat Res; 2002 Oct; 508(1-2):147-56. PubMed ID: 12379470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study.
    Shimada T; Tanaka K; Takenaka S; Foroozesh MK; Murayama N; Yamazaki H; Guengerich FP; Komori M
    Chem Res Toxicol; 2009 Jul; 22(7):1325-33. PubMed ID: 19563207
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.