1869 related articles for article (PubMed ID: 21734707)
41. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
Xu C; Yuan X; Pan Z; Shen G; Kim JH; Yu S; Khor TO; Li W; Ma J; Kong AN
Mol Cancer Ther; 2006 Aug; 5(8):1918-26. PubMed ID: 16928811
[TBL] [Abstract][Full Text] [Related]
42. Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.
He X; Chen MG; Lin GX; Ma Q
J Biol Chem; 2006 Aug; 281(33):23620-31. PubMed ID: 16785233
[TBL] [Abstract][Full Text] [Related]
43. Nrf2-Keap1 antioxidant defense and cell survival signaling are upregulated by 17β-estradiol in homocysteine-treated dopaminergic SH-SY5Y cells.
Chen CS; Tseng YT; Hsu YY; Lo YC
Neuroendocrinology; 2013; 97(3):232-41. PubMed ID: 22948038
[TBL] [Abstract][Full Text] [Related]
44. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A; Lamark T; Sjøttem E; Larsen KB; Awuh JA; Øvervatn A; McMahon M; Hayes JD; Johansen T
J Biol Chem; 2010 Jul; 285(29):22576-91. PubMed ID: 20452972
[TBL] [Abstract][Full Text] [Related]
45. Activation of Nrf2 in defense against cadmium-induced oxidative stress.
He X; Chen MG; Ma Q
Chem Res Toxicol; 2008 Jul; 21(7):1375-83. PubMed ID: 18512965
[TBL] [Abstract][Full Text] [Related]
46. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
Sun Z; Zhang S; Chan JY; Zhang DD
Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
[TBL] [Abstract][Full Text] [Related]
47. Oxaliplatin activates the Keap1/Nrf2 antioxidant system conferring protection against the cytotoxicity of anticancer drugs.
Wang XJ; Li Y; Luo L; Wang H; Chi Z; Xin A; Li X; Wu J; Tang X
Free Radic Biol Med; 2014 May; 70():68-77. PubMed ID: 24556415
[TBL] [Abstract][Full Text] [Related]
48. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Kaspar JW; Niture SK; Jaiswal AK
J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
[TBL] [Abstract][Full Text] [Related]
49. Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Hamada S; Shimosegawa T; Taguchi K; Nabeshima T; Yamamoto M; Masamune A
Am J Physiol Gastrointest Liver Physiol; 2018 Jan; 314(1):G65-G74. PubMed ID: 28971839
[TBL] [Abstract][Full Text] [Related]
50. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
Rojo AI; Medina-Campos ON; Rada P; Zúñiga-Toalá A; López-Gazcón A; Espada S; Pedraza-Chaverri J; Cuadrado A
Free Radic Biol Med; 2012 Jan; 52(2):473-87. PubMed ID: 22142471
[TBL] [Abstract][Full Text] [Related]
51. The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells.
Ci X; Lv H; Wang L; Wang X; Peng L; Qin FX; Cheng G
Chem Biol Interact; 2015 Sep; 239():192-9. PubMed ID: 26111761
[TBL] [Abstract][Full Text] [Related]
52. Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.
Muthusamy VR; Kannan S; Sadhaasivam K; Gounder SS; Davidson CJ; Boeheme C; Hoidal JR; Wang L; Rajasekaran NS
Free Radic Biol Med; 2012 Jan; 52(2):366-76. PubMed ID: 22051043
[TBL] [Abstract][Full Text] [Related]
53. Identification of an adaptor protein that facilitates Nrf2-Keap1 complex formation and modulates antioxidant response.
Zhang Y; Hou Y; Liu C; Li Y; Guo W; Wu JL; Xu D; You X; Pan Y; Chen Y
Free Radic Biol Med; 2016 Aug; 97():38-49. PubMed ID: 27212020
[TBL] [Abstract][Full Text] [Related]
54. The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis.
Zhou XL; Zhu CY; Wu ZG; Guo X; Zou W
Oncogene; 2019 May; 38(21):4028-4046. PubMed ID: 30692632
[TBL] [Abstract][Full Text] [Related]
55. The ROS-KRAS-Nrf2 axis in the control of the redox homeostasis and the intersection with survival-apoptosis pathways: Implications for photodynamic therapy.
Ferino A; Rapozzi V; Xodo LE
J Photochem Photobiol B; 2020 Jan; 202():111672. PubMed ID: 31778952
[TBL] [Abstract][Full Text] [Related]
56. Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle.
Miller CJ; Gounder SS; Kannan S; Goutam K; Muthusamy VR; Firpo MA; Symons JD; Paine R; Hoidal JR; Rajasekaran NS
Biochim Biophys Acta; 2012 Jun; 1822(6):1038-50. PubMed ID: 22366763
[TBL] [Abstract][Full Text] [Related]
57. Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation.
Park JS; Kang DH; Lee DH; Bae SH
Biochem Biophys Res Commun; 2015 Sep; 465(3):542-7. PubMed ID: 26282199
[TBL] [Abstract][Full Text] [Related]
58. LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in
Galan-Cobo A; Sitthideatphaiboon P; Qu X; Poteete A; Pisegna MA; Tong P; Chen PH; Boroughs LK; Rodriguez MLM; Zhang W; Parlati F; Wang J; Gandhi V; Skoulidis F; DeBerardinis RJ; Minna JD; Heymach JV
Cancer Res; 2019 Jul; 79(13):3251-3267. PubMed ID: 31040157
[TBL] [Abstract][Full Text] [Related]
59. Daphnetin activates the Nrf2-dependent antioxidant response to prevent arsenic-induced oxidative insult in human lung epithelial cells.
Lv X; Li Y; Xiao Q; Li D
Chem Biol Interact; 2019 Apr; 302():93-100. PubMed ID: 30738023
[TBL] [Abstract][Full Text] [Related]
60. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.
Blake DJ; Singh A; Kombairaju P; Malhotra D; Mariani TJ; Tuder RM; Gabrielson E; Biswal S
Am J Respir Cell Mol Biol; 2010 May; 42(5):524-36. PubMed ID: 19520915
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]