BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 21734808)

  • 1. Antitumor activity of mutant bacterial cytosine deaminase gene for colon cancer.
    Deng LY; Wang JP; Gui ZF; Shen LZ
    World J Gastroenterol; 2011 Jun; 17(24):2958-64. PubMed ID: 21734808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma.
    Kaliberov SA; Market JM; Gillespie GY; Krendelchtchikova V; Della Manna D; Sellers JC; Kaliberova LN; Black ME; Buchsbaum DJ
    Gene Ther; 2007 Jul; 14(14):1111-9. PubMed ID: 17495948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular chemotherapy of pancreatic cancer using novel mutant bacterial cytosine deaminase gene.
    Kaliberova LN; Della Manna DL; Krendelchtchikova V; Black ME; Buchsbaum DJ; Kaliberov SA
    Mol Cancer Ther; 2008 Sep; 7(9):2845-54. PubMed ID: 18790765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alanine-scanning mutagenesis reveals a cytosine deaminase mutant with altered substrate preference.
    Mahan SD; Ireton GC; Stoddard BL; Black ME
    Biochemistry; 2004 Jul; 43(28):8957-64. PubMed ID: 15248753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts.
    Liu J; Harada H; Ogura M; Shibata T; Hiraoka M
    Br J Cancer; 2007 Jun; 96(12):1871-8. PubMed ID: 17519901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Experimental studies on the treatment of colon cancer by cytosine deaminase gene and 5-fluorocytosine].
    Huang JH; Wang Y; Li CH; Zhong DG; Lü HY
    Zhonghua Zhong Liu Za Zhi; 2005 Jan; 27(1):6-8. PubMed ID: 15771788
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nanoparticle-delivered VEGF-silencing cassette and suicide gene expression cassettes inhibit colon carcinoma growth in vitro and in vivo.
    Leng A; Yang J; Liu T; Cui J; Li XH; Zhu Y; Xiong T; Chen Y
    Tumour Biol; 2011 Dec; 32(6):1103-11. PubMed ID: 21761115
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts.
    Kievit E; Bershad E; Ng E; Sethna P; Dev I; Lawrence TS; Rehemtulla A
    Cancer Res; 1999 Apr; 59(7):1417-21. PubMed ID: 10197605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts.
    Kievit E; Nyati MK; Ng E; Stegman LD; Parsels J; Ross BD; Rehemtulla A; Lawrence TS
    Cancer Res; 2000 Dec; 60(23):6649-55. PubMed ID: 11118048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.
    Fuchita M; Ardiani A; Zhao L; Serve K; Stoddard BL; Black ME
    Cancer Res; 2009 Jun; 69(11):4791-9. PubMed ID: 19487291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice].
    Huang ZJ; Feng QZ; You J; Xu L; Luo WY; Yi WC; Zeng YY; Luo Q
    Zhonghua Yi Xue Za Zhi; 2013 Jul; 93(28):2235-40. PubMed ID: 24169337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Specific CEA-producing colorectal carcinoma cell killing with recombinant adenoviral vector containing cytosine deaminase gene.
    Shen LZ; Wu WX; Xu DH; Zheng ZC; Liu XY; Ding Q; Hua YB; Yao K
    World J Gastroenterol; 2002 Apr; 8(2):270-5. PubMed ID: 11925606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative analysis of enzyme and pathway engineering strategies for 5FC-mediated suicide gene therapy applications.
    Johnson AJ; Ardiani A; Sanchez-Bonilla M; Black ME
    Cancer Gene Ther; 2011 Aug; 18(8):533-42. PubMed ID: 21394105
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminase.
    Park JI; Cao L; Platt VM; Huang Z; Stull RA; Dy EE; Sperinde JJ; Yokoyama JS; Szoka FC
    Mol Pharm; 2009; 6(3):801-12. PubMed ID: 19265397
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adenovirus-mediated interleukin-12 gene transfer combined with cytosine deaminase followed by 5-fluorocytosine treatment exerts potent antitumor activity in Renca tumor-bearing mice.
    Hwang KS; Cho WK; Yoo J; Yun HJ; Kim S; Im DS
    BMC Cancer; 2005 May; 5():51. PubMed ID: 15910693
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro and in vivo effect of 5-FC combined gene therapy with TNF-α and CD suicide gene on human laryngeal carcinoma cell line Hep-2.
    Chai LP; Wang ZF; Liang WY; Chen L; Chen D; Wang AX; Zhang ZQ
    PLoS One; 2013; 8(4):e61136. PubMed ID: 23593411
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytotoxic effect of replication-competent adenoviral vectors carrying L-plastin promoter regulated E1A and cytosine deaminase genes in cancers of the breast, ovary and colon.
    Akbulut H; Zhang L; Tang Y; Deisseroth A
    Cancer Gene Ther; 2003 May; 10(5):388-95. PubMed ID: 12719708
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine.
    Koyama F; Sawada H; Hirao T; Fujii H; Hamada H; Nakano H
    Cancer Gene Ther; 2000 Jul; 7(7):1015-22. PubMed ID: 10917204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor effect of cytosine deaminase/5-fluorocytosine suicide gene therapy system mediated by Bifidobacterium infantis on melanoma.
    Yi C; Huang Y; Guo ZY; Wang SR
    Acta Pharmacol Sin; 2005 May; 26(5):629-34. PubMed ID: 15842785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bifunctional chimeric SuperCD suicide gene -YCD: YUPRT fusion is highly effective in a rat hepatoma model.
    Graepler F; Lemken ML; Wybranietz WA; Schmidt U; Smirnow I; Gross CD; Spiegel M; Schenk A; Graf H; Lauer UA; Vonthein R; Gregor M; Armeanu S; Bitzer M; Lauer UM
    World J Gastroenterol; 2005 Nov; 11(44):6910-9. PubMed ID: 16437592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.