BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 21736285)

  • 1. Endonuclease active site plasticity allows DNA cleavage with diverse alkaline Earth and transition metal ions.
    Vasu K; Saravanan M; Nagaraja V
    ACS Chem Biol; 2011 Sep; 6(9):934-42. PubMed ID: 21736285
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of a manganese specific restriction endonuclease with nicking activity.
    Vasu K; Saravanan M; Rajendra BV; Nagaraja V
    Biochemistry; 2010 Sep; 49(38):8425-33. PubMed ID: 20734974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ca(2+) binding to the ExDxD motif regulates the DNA cleavage specificity of a promiscuous endonuclease.
    Nagamalleswari E; Vasu K; Nagaraja V
    Biochemistry; 2012 Nov; 51(44):8939-49. PubMed ID: 23072305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+.
    Saravanan M; Vasu K; Kanakaraj R; Rao DN; Nagaraja V
    Nucleic Acids Res; 2007; 35(8):2777-86. PubMed ID: 17430971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increasing cleavage specificity and activity of restriction endonuclease KpnI.
    Vasu K; Nagamalleswari E; Zahran M; Imhof P; Xu SY; Zhu Z; Chan SH; Nagaraja V
    Nucleic Acids Res; 2013 Nov; 41(21):9812-24. PubMed ID: 23963701
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.
    Saravanan M; Bujnicki JM; Cymerman IA; Rao DN; Nagaraja V
    Nucleic Acids Res; 2004; 32(20):6129-35. PubMed ID: 15562004
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites.
    Horton NC; Perona JJ
    Biochemistry; 2004 Jun; 43(22):6841-57. PubMed ID: 15170321
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Does the restriction endonuclease EcoRV employ a two-metal-Ion mechanism for DNA cleavage?
    Groll DH; Jeltsch A; Selent U; Pingoud A
    Biochemistry; 1997 Sep; 36(38):11389-401. PubMed ID: 9298958
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Domain organization and metal ion requirement of the Type IIS restriction endonuclease MnlI.
    Kriukiene E
    FEBS Lett; 2006 Nov; 580(26):6115-22. PubMed ID: 17055493
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigation of restriction enzyme cofactor requirements: a relationship between metal ion properties and sequence specificity.
    Bowen LM; Dupureur CM
    Biochemistry; 2003 Nov; 42(43):12643-53. PubMed ID: 14580211
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lanthanide spectroscopic studies of the dinuclear and Mg(II)-dependent PvuII restriction endonuclease.
    Bowen LM; Muller G; Riehl JP; Dupureur CM
    Biochemistry; 2004 Dec; 43(48):15286-95. PubMed ID: 15568821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease.
    Saravanan M; Vasu K; Ghosh S; Nagaraja V
    J Biol Chem; 2007 Nov; 282(44):32320-6. PubMed ID: 17785455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based redesign of the catalytic/metal binding site of Cfr10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues.
    Skirgaila R; Grazulis S; Bozic D; Huber R; Siksnys V
    J Mol Biol; 1998 Jun; 279(2):473-81. PubMed ID: 9642051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA cleavage by the EcoRV restriction endonuclease: roles of divalent metal ions in specificity and catalysis.
    Baldwin GS; Sessions RB; Erskine SG; Halford SE
    J Mol Biol; 1999 Apr; 288(1):87-103. PubMed ID: 10329128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ca(2+)-mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease.
    Chandrashekaran S; Saravanan M; Radha DR; Nagaraja V
    J Biol Chem; 2004 Nov; 279(48):49736-40. PubMed ID: 15375161
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Catalytic efficiency and sequence selectivity of a restriction endonuclease modulated by a distal manganese ion binding site.
    Sam MD; Horton NC; Nissan TA; Perona JJ
    J Mol Biol; 2001 Mar; 306(4):851-61. PubMed ID: 11243793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA binding specificity of MunI restriction endonuclease is controlled by pH and calcium ions: involvement of active site carboxylate residues.
    Lagunavicius A; Grazulis S; Balciunaite E; Vainius D; Siksnys V
    Biochemistry; 1997 Sep; 36(37):11093-9. PubMed ID: 9287152
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease.
    Cymerman IA; Obarska A; Skowronek KJ; Lubys A; Bujnicki JM
    Proteins; 2006 Dec; 65(4):867-76. PubMed ID: 17029241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Categoric prediction of metal ion mechanisms in the active sites of 17 select type II restriction endonucleases.
    Advani S; Mishra P; Dubey S; Thakur S
    Biochem Biophys Res Commun; 2010 Nov; 402(2):177-9. PubMed ID: 20888795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. One- and two-metal ion catalysis: global single-turnover kinetic analysis of the PvuII endonuclease mechanism.
    Xie F; Qureshi SH; Papadakos GA; Dupureur CM
    Biochemistry; 2008 Nov; 47(47):12540-50. PubMed ID: 18975919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.