BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 21737879)

  • 1. VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
    Passemard S; El Ghouzzi V; Nasser H; Verney C; Vodjdani G; Lacaud A; Lebon S; Laburthe M; Robberecht P; Nardelli J; Mani S; Verloes A; Gressens P; Lelièvre V
    J Clin Invest; 2011 Aug; 121(8):3071-87. PubMed ID: 21737879
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.
    Gruber R; Zhou Z; Sukchev M; Joerss T; Frappart PO; Wang ZQ
    Nat Cell Biol; 2011 Sep; 13(11):1325-34. PubMed ID: 21947081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of mitotic entry by microcephalin and its overlap with ATR signalling.
    Alderton GK; Galbiati L; Griffith E; Surinya KH; Neitzel H; Jackson AP; Jeggo PA; O'Driscoll M
    Nat Cell Biol; 2006 Jul; 8(7):725-33. PubMed ID: 16783362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly.
    Lin SY; Rai R; Li K; Xu ZX; Elledge SJ
    Proc Natl Acad Sci U S A; 2005 Oct; 102(42):15105-9. PubMed ID: 16217032
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA damage response in microcephaly development of MCPH1 mouse model.
    Zhou ZW; Tapias A; Bruhn C; Gruber R; Sukchev M; Wang ZQ
    DNA Repair (Amst); 2013 Aug; 12(8):645-55. PubMed ID: 23683352
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1.
    Xu X; Lee J; Stern DF
    J Biol Chem; 2004 Aug; 279(33):34091-4. PubMed ID: 15220350
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo.
    Rickmyre JL; Dasgupta S; Ooi DL; Keel J; Lee E; Kirschner MW; Waddell S; Lee LA
    J Cell Sci; 2007 Oct; 120(Pt 20):3565-77. PubMed ID: 17895362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice.
    Wang Y; Zong W; Sun W; Chen C; Wang ZQ; Li T
    Cells; 2022 Aug; 11(17):. PubMed ID: 36078123
    [No Abstract]   [Full Text] [Related]  

  • 9. Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1.
    Tibelius A; Marhold J; Zentgraf H; Heilig CE; Neitzel H; Ducommun B; Rauch A; Ho AD; Bartek J; Krämer A
    J Cell Biol; 2009 Jun; 185(7):1149-57. PubMed ID: 19546241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microcephaly Gene
    Jiang YN; Gao Y; Lai X; Li X; Liu G; Ding M; Wang Z; Guo Z; Qin Y; Li X; Sun L; Wang ZQ; Zhou ZW
    Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731817
    [No Abstract]   [Full Text] [Related]  

  • 11. Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function.
    Trimborn M; Ghani M; Walther DJ; Dopatka M; Dutrannoy V; Busche A; Meyer F; Nowak S; Nowak J; Zabel C; Klose J; Esquitino V; Garshasbi M; Kuss AW; Ropers HH; Mueller S; Poehlmann C; Gavvovidis I; Schindler D; Sperling K; Neitzel H
    PLoS One; 2010 Feb; 5(2):e9242. PubMed ID: 20169082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comprehensive review on the molecular genetics of autosomal recessive primary microcephaly (MCPH).
    Naveed M; Kazmi SK; Amin M; Asif Z; Islam U; Shahid K; Tehreem S
    Genet Res (Camb); 2018 Aug; 100():e7. PubMed ID: 30086807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The E3 ubiquitin ligase APC/C
    Liu X; Zong W; Li T; Wang Y; Xu X; Zhou ZW; Wang ZQ
    EMBO J; 2017 Dec; 36(24):3666-3681. PubMed ID: 29150431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autosomal Recessive Primary Microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum.
    Mahmood S; Ahmad W; Hassan MJ
    Orphanet J Rare Dis; 2011 Jun; 6():39. PubMed ID: 21668957
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensation.
    Leung JW; Leitch A; Wood JL; Shaw-Smith C; Metcalfe K; Bicknell LS; Jackson AP; Chen J
    J Biol Chem; 2011 Jun; 286(24):21393-400. PubMed ID: 21515671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.
    Journiac N; Gilabert-Juan J; Cipriani S; Benit P; Liu X; Jacquier S; Faivre V; Delahaye-Duriez A; Csaba Z; Hourcade T; Melinte E; Lebon S; Violle-Poirsier C; Oury JF; Adle-Biassette H; Wang ZQ; Mani S; Rustin P; Gressens P; Nardelli J
    Cell Rep; 2020 Apr; 31(2):107506. PubMed ID: 32294449
    [TBL] [Abstract][Full Text] [Related]  

  • 17. What primary microcephaly can tell us about brain growth.
    Cox J; Jackson AP; Bond J; Woods CG
    Trends Mol Med; 2006 Aug; 12(8):358-66. PubMed ID: 16829198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.
    Li R; Yang YG; Gao Y; Wang ZQ; Tong WM
    Cell Res; 2012 May; 22(5):859-72. PubMed ID: 22212482
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neurogenesis: premature mitotic entry lets cleavage planes take off!
    Singh P; Cabernard C
    Curr Biol; 2012 Jan; 22(1):R25-8. PubMed ID: 22240477
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MCPH1: A Novel Case Report and a Review of the Literature.
    Caraffi SG; Pollazzon M; Farooq M; Fatima A; Larsen LA; Zuntini R; Napoli M; Garavelli L
    Genes (Basel); 2022 Apr; 13(4):. PubMed ID: 35456440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.