BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 21741595)

  • 1. Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.
    Heuser M; Yun H; Berg T; Yung E; Argiropoulos B; Kuchenbauer F; Park G; Hamwi I; Palmqvist L; Lai CK; Leung M; Lin G; Chaturvedi A; Thakur BK; Iwasaki M; Bilenky M; Thiessen N; Robertson G; Hirst M; Kent D; Wilson NK; Göttgens B; Eaves C; Cleary ML; Marra M; Ganser A; Humphries RK
    Cancer Cell; 2011 Jul; 20(1):39-52. PubMed ID: 21741595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes.
    Wang GG; Pasillas MP; Kamps MP
    Mol Cell Biol; 2006 May; 26(10):3902-16. PubMed ID: 16648484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins.
    Shen WF; Montgomery JC; Rozenfeld S; Moskow JJ; Lawrence HJ; Buchberg AM; Largman C
    Mol Cell Biol; 1997 Nov; 17(11):6448-58. PubMed ID: 9343407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3.
    Argiropoulos B; Yung E; Xiang P; Lo CY; Kuchenbauer F; Palmqvist L; Reindl C; Heuser M; Sekulovic S; Rosten P; Muranyi A; Goh SL; Featherstone M; Humphries RK
    Blood; 2010 May; 115(20):4071-82. PubMed ID: 20237320
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Meis2 as a critical player in MN1-induced leukemia.
    Lai CK; Norddahl GL; Maetzig T; Rosten P; Lohr T; Sanchez Milde L; von Krosigk N; Docking TR; Heuser M; Karsan A; Humphries RK
    Blood Cancer J; 2017 Sep; 7(9):e613. PubMed ID: 28960191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mapping of MN1 sequences necessary for myeloid transformation.
    Kandilci A; Surtel J; Janke L; Neale G; Terranova S; Grosveld GC
    PLoS One; 2013; 8(4):e61706. PubMed ID: 23626719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
    Riedel SS; Haladyna JN; Bezzant M; Stevens B; Pollyea DA; Sinha AU; Armstrong SA; Wei Q; Pollock RM; Daigle SR; Jordan CT; Ernst P; Neff T; Bernt KM
    J Clin Invest; 2016 Apr; 126(4):1438-50. PubMed ID: 26927674
    [TBL] [Abstract][Full Text] [Related]  

  • 9. GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis.
    Wang Z; Iwasaki M; Ficara F; Lin C; Matheny C; Wong SH; Smith KS; Cleary ML
    Cancer Cell; 2010 Jun; 17(6):597-608. PubMed ID: 20541704
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation.
    Morgado E; Albouhair S; Lavau C
    Blood; 2007 May; 109(9):4020-2. PubMed ID: 17202314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
    Schneider E; Pochert N; Ruess C; MacPhee L; Escano L; Miller C; Krowiorz K; Delsing Malmberg E; Heravi-Moussavi A; Lorzadeh A; Ashouri A; Grasedieck S; Sperb N; Kumar Kopparapu P; Iben S; Staffas A; Xiang P; Rösler R; Kanduri M; Larsson E; Fogelstrand L; Döhner H; Döhner K; Wiese S; Hirst M; Keith Humphries R; Palmqvist L; Kuchenbauer F; Rouhi A
    Leukemia; 2020 May; 34(5):1253-1265. PubMed ID: 31768018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.
    Wang GG; Pasillas MP; Kamps MP
    Blood; 2005 Jul; 106(1):254-64. PubMed ID: 15755900
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
    Mohr S; Doebele C; Comoglio F; Berg T; Beck J; Bohnenberger H; Alexe G; Corso J; Ströbel P; Wachter A; Beissbarth T; Schnütgen F; Cremer A; Haetscher N; Göllner S; Rouhi A; Palmqvist L; Rieger MA; Schroeder T; Bönig H; Müller-Tidow C; Kuchenbauer F; Schütz E; Green AR; Urlaub H; Stegmaier K; Humphries RK; Serve H; Oellerich T
    Cancer Cell; 2017 Apr; 31(4):549-562.e11. PubMed ID: 28399410
    [TBL] [Abstract][Full Text] [Related]  

  • 14. C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.
    Bisaillon R; Wilhelm BT; Krosl J; Sauvageau G
    Blood; 2011 Oct; 118(17):4682-9. PubMed ID: 21900201
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.
    Jiang X; Huang H; Li Z; He C; Li Y; Chen P; Gurbuxani S; Arnovitz S; Hong GM; Price C; Ren H; Kunjamma RB; Neilly MB; Salat J; Wunderlich M; Slany RK; Zhang Y; Larson RA; Le Beau MM; Mulloy JC; Rowley JD; Chen J
    Proc Natl Acad Sci U S A; 2012 Nov; 109(47):19397-402. PubMed ID: 23132946
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
    Wong P; Iwasaki M; Somervaille TC; So CW; Cleary ML
    Genes Dev; 2007 Nov; 21(21):2762-74. PubMed ID: 17942707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
    Velu CS; Chaubey A; Phelan JD; Horman SR; Wunderlich M; Guzman ML; Jegga AG; Zeleznik-Le NJ; Chen J; Mulloy JC; Cancelas JA; Jordan CT; Aronow BJ; Marcucci G; Bhat B; Gebelein B; Grimes HL
    J Clin Invest; 2014 Jan; 124(1):222-36. PubMed ID: 24334453
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3.
    Argiropoulos B; Palmqvist L; Yung E; Kuchenbauer F; Heuser M; Sly LM; Wan A; Krystal G; Humphries RK
    Exp Hematol; 2008 Jul; 36(7):845-59. PubMed ID: 18375036
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
    Willer A; Jakobsen JS; Ohlsson E; Rapin N; Waage J; Billing M; Bullinger L; Karlsson S; Porse BT
    Leukemia; 2015 May; 29(5):1018-31. PubMed ID: 25349154
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Historical Relationship Between Meis1 and Leukemia.
    Meriç N; Kocabaş F
    Adv Exp Med Biol; 2022; 1387():127-144. PubMed ID: 35304708
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.