221 related articles for article (PubMed ID: 21741595)
21. Tumorigenesis by Meis1 overexpression is accompanied by a change of DNA target-sequence specificity which allows binding to the AP-1 element.
Dardaei L; Penkov D; Mathiasen L; Bora P; Morelli MJ; Blasi F
Oncotarget; 2015 Sep; 6(28):25175-87. PubMed ID: 26259236
[TBL] [Abstract][Full Text] [Related]
22. MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
Muntean AG; Chen W; Jones M; Granowicz EM; Maillard I; Hess JL
Blood; 2013 Sep; 122(11):1914-22. PubMed ID: 23900238
[TBL] [Abstract][Full Text] [Related]
23. Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.
Sharma A; Yun H; Jyotsana N; Chaturvedi A; Schwarzer A; Yung E; Lai CK; Kuchenbauer F; Argiropoulos B; Görlich K; Ganser A; Humphries RK; Heuser M
Leukemia; 2015 Jan; 29(1):157-68. PubMed ID: 24957708
[TBL] [Abstract][Full Text] [Related]
24. Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia.
Thorsteinsdottir U; Kroon E; Jerome L; Blasi F; Sauvageau G
Mol Cell Biol; 2001 Jan; 21(1):224-34. PubMed ID: 11113197
[TBL] [Abstract][Full Text] [Related]
25. Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.
Lu R; Wang P; Parton T; Zhou Y; Chrysovergis K; Rockowitz S; Chen WY; Abdel-Wahab O; Wade PA; Zheng D; Wang GG
Cancer Cell; 2016 Jul; 30(1):92-107. PubMed ID: 27344947
[TBL] [Abstract][Full Text] [Related]
26. Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.
Heuser M; Sly LM; Argiropoulos B; Kuchenbauer F; Lai C; Weng A; Leung M; Lin G; Brookes C; Fung S; Valk PJ; Delwel R; Löwenberg B; Krystal G; Humphries RK
Blood; 2009 Nov; 114(19):3983-93. PubMed ID: 19667399
[TBL] [Abstract][Full Text] [Related]
27. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1.
Calvo KR; Sykes DB; Pasillas MP; Kamps MP
Oncogene; 2002 Jun; 21(27):4247-56. PubMed ID: 12082612
[TBL] [Abstract][Full Text] [Related]
28. Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.
Kühn MW; Song E; Feng Z; Sinha A; Chen CW; Deshpande AJ; Cusan M; Farnoud N; Mupo A; Grove C; Koche R; Bradner JE; de Stanchina E; Vassiliou GS; Hoshii T; Armstrong SA
Cancer Discov; 2016 Oct; 6(10):1166-1181. PubMed ID: 27535106
[TBL] [Abstract][Full Text] [Related]
29. PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway.
Zhou J; Wu J; Li B; Liu D; Yu J; Yan X; Zheng S; Wang J; Zhang L; Zhang L; He F; Li Q; Chen A; Zhang Y; Zhao X; Guan Y; Zhao X; Yan J; Ni J; Nobrega MA; Löwenberg B; Delwel R; Valk PJ; Kumar A; Xie L; Tenen DG; Huang G; Wang QF
Leukemia; 2014 Jul; 28(7):1436-48. PubMed ID: 24445817
[TBL] [Abstract][Full Text] [Related]
30. Initiation of MLL-rearranged AML is dependent on C/EBPα.
Ohlsson E; Hasemann MS; Willer A; Lauridsen FK; Rapin N; Jendholm J; Porse BT
J Exp Med; 2014 Jan; 211(1):5-13. PubMed ID: 24367003
[TBL] [Abstract][Full Text] [Related]
31. Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9.
Kawagoe H; Grosveld GC
Blood; 2005 Dec; 106(13):4269-77. PubMed ID: 16105979
[TBL] [Abstract][Full Text] [Related]
32. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.
Bansal D; Scholl C; Fröhling S; McDowell E; Lee BH; Döhner K; Ernst P; Davidson AJ; Daley GQ; Zon LI; Gilliland DG; Huntly BJ
Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16924-9. PubMed ID: 17068127
[TBL] [Abstract][Full Text] [Related]
33. Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
Garzon R; Garofalo M; Martelli MP; Briesewitz R; Wang L; Fernandez-Cymering C; Volinia S; Liu CG; Schnittger S; Haferlach T; Liso A; Diverio D; Mancini M; Meloni G; Foa R; Martelli MF; Mecucci C; Croce CM; Falini B
Proc Natl Acad Sci U S A; 2008 Mar; 105(10):3945-50. PubMed ID: 18308931
[TBL] [Abstract][Full Text] [Related]
34. HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis.
Hu YL; Fong S; Ferrell C; Largman C; Shen WF
Mol Cell Biol; 2009 Sep; 29(18):5181-92. PubMed ID: 19620287
[TBL] [Abstract][Full Text] [Related]
35. Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST.
Chowdhury AH; Ramroop JR; Upadhyay G; Sengupta A; Andrzejczyk A; Saleque S
PLoS One; 2013; 8(1):e53666. PubMed ID: 23308270
[TBL] [Abstract][Full Text] [Related]
36. Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1.
Pineault N; Abramovich C; Ohta H; Humphries RK
Mol Cell Biol; 2004 Mar; 24(5):1907-17. PubMed ID: 14966272
[TBL] [Abstract][Full Text] [Related]
37. Menin is necessary for long term maintenance of meningioma-1 driven leukemia.
Libbrecht C; Xie HM; Kingsley MC; Haladyna JN; Riedel SS; Alikarami F; Lenard A; McGeehan GM; Ernst P; Bernt KM
Leukemia; 2021 May; 35(5):1405-1417. PubMed ID: 33542482
[TBL] [Abstract][Full Text] [Related]
38. Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML.
Riedel SS; Lu C; Xie HM; Nestler K; Vermunt MW; Lenard A; Bennett L; Speck NA; Hanamura I; Lessard JA; Blobel GA; Garcia BA; Bernt KM
Mol Cell; 2021 Jun; 81(11):2332-2348.e9. PubMed ID: 33974912
[TBL] [Abstract][Full Text] [Related]
39. Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13.
Imren S; Heuser M; Gasparetto M; Beer PA; Norddahl GL; Xiang P; Chen L; Berg T; Rhyasen GW; Rosten P; Park G; Moon Y; Weng AP; Eaves CJ; Humphries RK
Blood; 2014 Dec; 124(24):3608-12. PubMed ID: 25339361
[TBL] [Abstract][Full Text] [Related]
40. MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia.
Roychoudhury J; Clark JP; Gracia-Maldonado G; Unnisa Z; Wunderlich M; Link KA; Dasgupta N; Aronow B; Huang G; Mulloy JC; Kumar AR
Blood; 2015 Apr; 125(16):2544-52. PubMed ID: 25740828
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
