129 related articles for article (PubMed ID: 21741838)
1. Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.
Ryckmans T; Aubdool AA; Bodkin JV; Cox P; Brain SD; Dupont T; Fairman E; Hashizume Y; Ishii N; Kato T; Kitching L; Newman J; Omoto K; Rawson D; Strover J
Bioorg Med Chem Lett; 2011 Aug; 21(16):4857-9. PubMed ID: 21741838
[TBL] [Abstract][Full Text] [Related]
2. Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists.
Gijsen HJ; Berthelot D; De Cleyn MA; Geuens I; Brône B; Mercken M
Bioorg Med Chem Lett; 2012 Jan; 22(2):797-800. PubMed ID: 22222037
[TBL] [Abstract][Full Text] [Related]
3. 7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Baraldi PG; Romagnoli R; Saponaro G; Aghazadeh Tabrizi M; Baraldi S; Pedretti P; Fusi C; Nassini R; Materazzi S; Geppetti P; Preti D
Bioorg Med Chem; 2012 Mar; 20(5):1690-8. PubMed ID: 22325155
[TBL] [Abstract][Full Text] [Related]
4. Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597).
Niforatos W; Zhang XF; Lake MR; Walter KA; Neelands T; Holzman TF; Scott VE; Faltynek CR; Moreland RB; Chen J
Mol Pharmacol; 2007 May; 71(5):1209-16. PubMed ID: 17314320
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.
Morera E; De Petrocellis L; Morera L; Moriello AS; Nalli M; Di Marzo V; Ortar G
Bioorg Med Chem Lett; 2012 Feb; 22(4):1674-7. PubMed ID: 22257892
[TBL] [Abstract][Full Text] [Related]
6. TRPA1.
García-Añoveros J; Nagata K
Handb Exp Pharmacol; 2007; (179):347-62. PubMed ID: 17217068
[TBL] [Abstract][Full Text] [Related]
7. Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor.
Defalco J; Steiger D; Gustafson A; Emerling DE; Kelly MG; Duncton MA
Bioorg Med Chem Lett; 2010 Jan; 20(1):276-9. PubMed ID: 19945872
[TBL] [Abstract][Full Text] [Related]
8. Activation of TRPA1 by farnesyl thiosalicylic acid.
Maher M; Ao H; Banke T; Nasser N; Wu NT; Breitenbucher JG; Chaplan SR; Wickenden AD
Mol Pharmacol; 2008 Apr; 73(4):1225-34. PubMed ID: 18171730
[TBL] [Abstract][Full Text] [Related]
9. A Potent and Site-Selective Agonist of TRPA1.
Takaya J; Mio K; Shiraishi T; Kurokawa T; Otsuka S; Mori Y; Uesugi M
J Am Chem Soc; 2015 Dec; 137(50):15859-64. PubMed ID: 26630251
[TBL] [Abstract][Full Text] [Related]
10. Analogues of morphanthridine and the tear gas dibenz[b,f][1,4]oxazepine (CR) as extremely potent activators of the human transient receptor potential ankyrin 1 (TRPA1) channel.
Gijsen HJ; Berthelot D; Zaja M; Brône B; Geuens I; Mercken M
J Med Chem; 2010 Oct; 53(19):7011-20. PubMed ID: 20806939
[TBL] [Abstract][Full Text] [Related]
11. Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.
Yassaka RT; Inagaki H; Fujino T; Nakatani K; Kubo T
Neurosci Res; 2010 Jan; 66(1):99-105. PubMed ID: 19808063
[TBL] [Abstract][Full Text] [Related]
12. The anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel.
Babes A; Fischer MJ; Filipovic M; Engel MA; Flonta ML; Reeh PW
Eur J Pharmacol; 2013 Mar; 704(1-3):15-22. PubMed ID: 23461853
[TBL] [Abstract][Full Text] [Related]
13. Transient receptor potential A1 mediates an osmotically activated ion channel.
Zhang XF; Chen J; Faltynek CR; Moreland RB; Neelands TR
Eur J Neurosci; 2008 Feb; 27(3):605-11. PubMed ID: 18279313
[TBL] [Abstract][Full Text] [Related]
14. Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
Copeland KW; Boezio AA; Cheung E; Lee J; Olivieri P; Schenkel LB; Wan Q; Wang W; Wells MC; Youngblood B; Gavva NR; Lehto SG; Geuns-Meyer S
Bioorg Med Chem Lett; 2014 Aug; 24(15):3464-8. PubMed ID: 24953819
[TBL] [Abstract][Full Text] [Related]
15. Recent advances in the biology and medicinal chemistry of TRPA1.
Rech JC; Eckert WA; Maher MP; Banke T; Bhattacharya A; Wickenden AD
Future Med Chem; 2010 May; 2(5):843-58. PubMed ID: 21426205
[TBL] [Abstract][Full Text] [Related]
16. TRPA1 modulators in preclinical development.
Viana F; Ferrer-Montiel A
Expert Opin Ther Pat; 2009 Dec; 19(12):1787-99. PubMed ID: 19939193
[TBL] [Abstract][Full Text] [Related]
17. Sustained TRPA1 activation in vivo.
Koivisto A
Acta Physiol (Oxf); 2012 Feb; 204(2):248-54. PubMed ID: 21518269
[TBL] [Abstract][Full Text] [Related]
18. Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels.
Ma S; G G; Ak VE; Jf D; H H
Pak J Pharm Sci; 2008 Oct; 21(4):370-8. PubMed ID: 18930858
[TBL] [Abstract][Full Text] [Related]
19. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.
Eid SR; Crown ED; Moore EL; Liang HA; Choong KC; Dima S; Henze DA; Kane SA; Urban MO
Mol Pain; 2008 Oct; 4():48. PubMed ID: 18954467
[TBL] [Abstract][Full Text] [Related]
20. Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.
Meents JE; Fischer MJ; McNaughton PA
J Physiol; 2016 Nov; 594(22):6643-6660. PubMed ID: 27307078
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
