173 related articles for article (PubMed ID: 21744858)
1. Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.
Abate C; Hornick JR; Spitzer D; Hawkins WG; Niso M; Perrone R; Berardi F
J Med Chem; 2011 Aug; 54(16):5858-67. PubMed ID: 21744858
[TBL] [Abstract][Full Text] [Related]
2. Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.
Abate C; Niso M; Marottoli R; Riganti C; Ghigo D; Ferorelli S; Ossato G; Perrone R; Lacivita E; Lamb DC; Berardi F
J Med Chem; 2014 Apr; 57(8):3314-23. PubMed ID: 24697311
[TBL] [Abstract][Full Text] [Related]
3. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
[TBL] [Abstract][Full Text] [Related]
4. Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.
Pati ML; Hornick JR; Niso M; Berardi F; Spitzer D; Abate C; Hawkins W
BMC Cancer; 2017 Jan; 17(1):51. PubMed ID: 28086830
[TBL] [Abstract][Full Text] [Related]
5. Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with added polar functionality and reduced lipophilicity for potential use as positron emission tomography radiotracers.
Abate C; Niso M; Lacivita E; Mosier PD; Toscano A; Perrone R
J Med Chem; 2011 Feb; 54(4):1022-32. PubMed ID: 21229979
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging.
Selivanova SV; Toscano A; Abate C; Berardi F; Müller A; Krämer SD; Schibli R; Ametamey SM
Nucl Med Biol; 2015 Apr; 42(4):399-405. PubMed ID: 25637276
[TBL] [Abstract][Full Text] [Related]
7. Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
Moussa IA; Banister SD; Akladios FN; Chua SW; Kassiou M
Bioorg Med Chem Lett; 2011 Oct; 21(19):5707-10. PubMed ID: 21871797
[TBL] [Abstract][Full Text] [Related]
8. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
9. 1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review.
Berardi F; Abate C; Ferorelli S; Colabufo NA; Perrone R
Cent Nerv Syst Agents Med Chem; 2009 Sep; 9(3):205-19. PubMed ID: 20021355
[TBL] [Abstract][Full Text] [Related]
10. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
[TBL] [Abstract][Full Text] [Related]
11. Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers.
Abate C; Ferorelli S; Contino M; Marottoli R; Colabufo NA; Perrone R; Berardi F
Eur J Med Chem; 2011 Sep; 46(9):4733-41. PubMed ID: 21684636
[TBL] [Abstract][Full Text] [Related]
12. 2-Aminopyridine derivatives as potential σ(2) receptor antagonists.
Abate C; Ferorelli S; Niso M; Lovicario C; Infantino V; Convertini P; Perrone R; Berardi F
ChemMedChem; 2012 Oct; 7(10):1847-57. PubMed ID: 22890883
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, radioiodination and in vitro and in vivo sigma receptor studies of N-1-allyl-N´-4-phenethylpiperazine analogs.
Lever SZ; Xu R; Fan KH; Fergason-Cantrell EA; Carmack TL; Watkinson LD; Lever JR
Nucl Med Biol; 2012 Apr; 39(3):401-14. PubMed ID: 22172395
[TBL] [Abstract][Full Text] [Related]
14. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Lacivita E; Tortorella V; Leonardi A; Poggesi E; Testa R
J Med Chem; 2001 Dec; 44(25):4431-42. PubMed ID: 11728188
[TBL] [Abstract][Full Text] [Related]
15. Subcellular localization of sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy.
Zeng C; Vangveravong S; Xu J; Chang KC; Hotchkiss RS; Wheeler KT; Shen D; Zhuang ZP; Kung HF; Mach RH
Cancer Res; 2007 Jul; 67(14):6708-16. PubMed ID: 17638881
[TBL] [Abstract][Full Text] [Related]
16. Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer.
Abate C; Elenewski J; Niso M; Berardi F; Colabufo NA; Azzariti A; Perrone R; Glennon RA
ChemMedChem; 2010 Feb; 5(2):268-73. PubMed ID: 20077462
[TBL] [Abstract][Full Text] [Related]
17. Development of sigma-1 (σ1) receptor fluorescent ligands as versatile tools to study σ1 receptors.
Abate C; Riganti C; Pati ML; Ghigo D; Berardi F; Mavlyutov T; Guo LW; Ruoho A
Eur J Med Chem; 2016 Jan; 108():577-585. PubMed ID: 26717207
[TBL] [Abstract][Full Text] [Related]
18. Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.
Hornick JR; Vangveravong S; Spitzer D; Abate C; Berardi F; Goedegebuure P; Mach RH; Hawkins WG
J Exp Clin Cancer Res; 2012 May; 31(1):41. PubMed ID: 22551149
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors.
Kassiou M; Dannals RF; Liu X; Wong DF; Ravert HT; Scheffel UA
Bioorg Med Chem; 2005 Jun; 13(11):3623-6. PubMed ID: 15862990
[TBL] [Abstract][Full Text] [Related]
20. Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization.
Colabufo NA; Abate C; Contino M; Inglese C; Ferorelli S; Berardi F; Perrone R
Bioorg Med Chem Lett; 2008 Mar; 18(6):2183-7. PubMed ID: 18178434
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
