These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
235 related articles for article (PubMed ID: 21746917)
1. Targeted Sos1 deletion reveals its critical role in early T-cell development. Kortum RL; Sommers CL; Alexander CP; Pinski JM; Li W; Grinberg A; Lee J; Love PE; Samelson LE Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12407-12. PubMed ID: 21746917 [TBL] [Abstract][Full Text] [Related]
2. Deconstructing Ras signaling in the thymus. Kortum RL; Sommers CL; Pinski JM; Alexander CP; Merrill RK; Li W; Love PE; Samelson LE Mol Cell Biol; 2012 Jul; 32(14):2748-59. PubMed ID: 22586275 [TBL] [Abstract][Full Text] [Related]
3. Sos1 regulates sustained TCR-mediated Erk activation. Poltorak M; Meinert I; Stone JC; Schraven B; Simeoni L Eur J Immunol; 2014 May; 44(5):1535-40. PubMed ID: 24497027 [TBL] [Abstract][Full Text] [Related]
4. The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo. Kortum RL; Balagopalan L; Alexander CP; Garcia J; Pinski JM; Merrill RK; Nguyen PH; Li W; Agarwal I; Akpan IO; Sommers CL; Samelson LE Sci Signal; 2013 Nov; 6(301):ra99. PubMed ID: 24222714 [TBL] [Abstract][Full Text] [Related]
5. Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells. Kortum RL; Rouquette-Jazdanian AK; Samelson LE Trends Immunol; 2013 Jun; 34(6):259-68. PubMed ID: 23506953 [TBL] [Abstract][Full Text] [Related]
6. Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival. Baltanás FC; Pérez-Andrés M; Ginel-Picardo A; Diaz D; Jimeno D; Liceras-Boillos P; Kortum RL; Samelson LE; Orfao A; Santos E Mol Cell Biol; 2013 Nov; 33(22):4562-78. PubMed ID: 24043312 [TBL] [Abstract][Full Text] [Related]
7. Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. Reynolds LF; de Bettignies C; Norton T; Beeser A; Chernoff J; Tybulewicz VL J Biol Chem; 2004 Apr; 279(18):18239-46. PubMed ID: 14764585 [TBL] [Abstract][Full Text] [Related]
8. RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4. Golec DP; Dower NA; Stone JC; Baldwin TA PLoS One; 2013; 8(1):e53300. PubMed ID: 23308188 [TBL] [Abstract][Full Text] [Related]
9. Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice. Chen X; Priatel JJ; Chow MT; Teh HS J Immunol; 2008 May; 180(9):5973-82. PubMed ID: 18424717 [TBL] [Abstract][Full Text] [Related]
10. Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis. Liceras-Boillos P; Jimeno D; García-Navas R; Lorenzo-Martín LF; Menacho-Marquez M; Segrelles C; Gómez C; Calzada N; Fuentes-Mateos R; Paramio JM; Bustelo XR; Baltanás FC; Santos E Mol Cell Biol; 2018 Aug; 38(16):. PubMed ID: 29844066 [TBL] [Abstract][Full Text] [Related]
11. The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties. Qian X; Esteban L; Vass WC; Upadhyaya C; Papageorge AG; Yienger K; Ward JM; Lowy DR; Santos E EMBO J; 2000 Feb; 19(4):642-54. PubMed ID: 10675333 [TBL] [Abstract][Full Text] [Related]
12. Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration. Guittard G; Kortum RL; Balagopalan L; Çuburu N; Nguyen P; Sommers CL; Samelson LE Eur J Immunol; 2015 Aug; 45(8):2389-95. PubMed ID: 25973715 [TBL] [Abstract][Full Text] [Related]
13. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development. Priatel JJ; Chen X; Dhanji S; Abraham N; Teh HS J Immunol; 2006 Aug; 177(3):1470-80. PubMed ID: 16849453 [TBL] [Abstract][Full Text] [Related]
14. Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation. Jun JE; Kulhanek KR; Chen H; Chakraborty A; Roose JP Sci Signal; 2019 Jul; 12(591):. PubMed ID: 31337738 [TBL] [Abstract][Full Text] [Related]
15. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Dower NA; Stang SL; Bottorff DA; Ebinu JO; Dickie P; Ostergaard HL; Stone JC Nat Immunol; 2000 Oct; 1(4):317-21. PubMed ID: 11017103 [TBL] [Abstract][Full Text] [Related]
16. SOS1, ARHGEF1, and DOCK2 rho-GEFs Mediate JAK-Dependent LFA-1 Activation by Chemokines. Toffali L; Montresor A; Mirenda M; Scita G; Laudanna C J Immunol; 2017 Jan; 198(2):708-717. PubMed ID: 27986909 [TBL] [Abstract][Full Text] [Related]
17. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. Priatel JJ; Teh SJ; Dower NA; Stone JC; Teh HS Immunity; 2002 Nov; 17(5):617-27. PubMed ID: 12433368 [TBL] [Abstract][Full Text] [Related]
18. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. Maillard I; Tu L; Sambandam A; Yashiro-Ohtani Y; Millholland J; Keeshan K; Shestova O; Xu L; Bhandoola A; Pear WS J Exp Med; 2006 Oct; 203(10):2239-45. PubMed ID: 16966428 [TBL] [Abstract][Full Text] [Related]
19. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth. Depeille P; Henricks LM; van de Ven RA; Lemmens E; Wang CY; Matli M; Werb Z; Haigis KM; Donner D; Warren R; Roose JP Nat Cell Biol; 2015 Jun; 17(6):804-15. PubMed ID: 26005835 [TBL] [Abstract][Full Text] [Related]
20. IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens. Deshpande P; Cavanagh MM; Le Saux S; Singh K; Weyand CM; Goronzy JJ J Immunol; 2013 Feb; 190(4):1416-23. PubMed ID: 23325887 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]