These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

411 related articles for article (PubMed ID: 21747117)

  • 1. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
    Mazumdar T; Devecchio J; Agyeman A; Shi T; Houghton JA
    Cancer Res; 2011 Sep; 71(17):5904-14. PubMed ID: 21747117
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
    Mazumdar T; DeVecchio J; Agyeman A; Shi T; Houghton JA
    Oncotarget; 2011 Aug; 2(8):638-45. PubMed ID: 21860067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A; Mazumdar T; Houghton JA
    Oncotarget; 2012 Aug; 3(8):854-68. PubMed ID: 23097684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hedgehog signaling drives cellular survival in human colon carcinoma cells.
    Mazumdar T; DeVecchio J; Shi T; Jones J; Agyeman A; Houghton JA
    Cancer Res; 2011 Feb; 71(3):1092-102. PubMed ID: 21135115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
    Agyeman A; Jha BK; Mazumdar T; Houghton JA
    Oncotarget; 2014 Jun; 5(12):4492-503. PubMed ID: 24962990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells.
    Mazumdar T; Sandhu R; Qadan M; DeVecchio J; Magloire V; Agyeman A; Li B; Houghton JA
    PLoS One; 2013; 8(9):e75253. PubMed ID: 24086482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.
    Zhang R; Wu J; Ferrandon S; Glowacki KJ; Houghton JA
    Oncotarget; 2016 Dec; 7(49):80190-80207. PubMed ID: 27863397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
    Yoshimoto AN; Bernardazzi C; Carneiro AJ; Elia CC; Martinusso CA; Ventura GM; Castelo-Branco MT; de Souza HS
    PLoS One; 2012; 7(9):e45332. PubMed ID: 23028941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.
    Hu MC; Mo R; Bhella S; Wilson CW; Chuang PT; Hui CC; Rosenblum ND
    Development; 2006 Feb; 133(3):569-78. PubMed ID: 16396903
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
    Barsoum I; Yao HH
    Biol Reprod; 2011 May; 84(5):894-9. PubMed ID: 21209421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gant61 ameliorates CCl
    Jiayuan S; Junyan Y; Xiangzhen W; Zuping L; Jian N; Baowei H; Lifang J
    Toxicol Appl Pharmacol; 2020 Jan; 387():114853. PubMed ID: 31816328
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.
    Huang L; Walter V; Hayes DN; Onaitis M
    Clin Cancer Res; 2014 Mar; 20(6):1566-75. PubMed ID: 24423612
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gli2 expression and human bladder transitional carcinoma cell invasiveness.
    Mechlin CW; Tanner MJ; Chen M; Buttyan R; Levin RM; Mian BM
    J Urol; 2010 Jul; 184(1):344-51. PubMed ID: 20488474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma.
    Yan M; Wang L; Zuo H; Zhang Z; Chen W; Mao L; Zhang P
    Oral Oncol; 2011 Jun; 47(6):504-9. PubMed ID: 21536478
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
    Kawabata N; Ijiri K; Ishidou Y; Yamamoto T; Nagao H; Nagano S; Maeda S; Komiya S; Setoguchi T
    Int J Oncol; 2011 Oct; 39(4):899-906. PubMed ID: 21674124
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Smoothened-independent activation of hedgehog signaling by rearranged during transfection promotes neuroblastoma cell proliferation and tumor growth.
    Ruan H; Luo H; Wang J; Ji X; Zhang Z; Wu J; Zhang X; Wu X
    Biochim Biophys Acta; 2016 Sep; 1860(9):1961-72. PubMed ID: 27316313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.