218 related articles for article (PubMed ID: 21750531)
1. Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery.
Whitehead KA; Sahay G; Li GZ; Love KT; Alabi CA; Ma M; Zurenko C; Querbes W; Langer RS; Anderson DG
Mol Ther; 2011 Sep; 19(9):1688-94. PubMed ID: 21750531
[TBL] [Abstract][Full Text] [Related]
2. Neutralization of negative charges of siRNA results in improved safety and efficient gene silencing activity of lipid nanoparticles loaded with high levels of siRNA.
Sato Y; Matsui H; Sato R; Harashima H
J Control Release; 2018 Aug; 284():179-187. PubMed ID: 29936118
[TBL] [Abstract][Full Text] [Related]
3. Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo.
Sato Y; Hashiba K; Sasaki K; Maeki M; Tokeshi M; Harashima H
J Control Release; 2019 Feb; 295():140-152. PubMed ID: 30610950
[TBL] [Abstract][Full Text] [Related]
4. Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA.
Ball RL; Hajj KA; Vizelman J; Bajaj P; Whitehead KA
Nano Lett; 2018 Jun; 18(6):3814-3822. PubMed ID: 29694050
[TBL] [Abstract][Full Text] [Related]
5. Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA.
Spagnou S; Miller AD; Keller M
Biochemistry; 2004 Oct; 43(42):13348-56. PubMed ID: 15491141
[TBL] [Abstract][Full Text] [Related]
6. Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid.
Suzuki Y; Ishihara H
Int J Pharm; 2016 Aug; 510(1):350-8. PubMed ID: 27374199
[TBL] [Abstract][Full Text] [Related]
7. Multifunctional cationic lipid-based nanoparticles facilitate endosomal escape and reduction-triggered cytosolic siRNA release.
Gujrati M; Malamas A; Shin T; Jin E; Sun Y; Lu ZR
Mol Pharm; 2014 Aug; 11(8):2734-44. PubMed ID: 25020033
[TBL] [Abstract][Full Text] [Related]
8. Biodegradable lipid nanoparticles induce a prolonged RNA interference-mediated protein knockdown and show rapid hepatic clearance in mice and nonhuman primates.
Suzuki Y; Hyodo K; Suzuki T; Tanaka Y; Kikuchi H; Ishihara H
Int J Pharm; 2017 Mar; 519(1-2):34-43. PubMed ID: 28089936
[TBL] [Abstract][Full Text] [Related]
9. Multifunctional pH-Sensitive Amino Lipids for siRNA Delivery.
Gujrati M; Vaidya A; Lu ZR
Bioconjug Chem; 2016 Jan; 27(1):19-35. PubMed ID: 26629982
[TBL] [Abstract][Full Text] [Related]
10. Alkane-modified short polyethyleneimine for siRNA delivery.
Schroeder A; Dahlman JE; Sahay G; Love KT; Jiang S; Eltoukhy AA; Levins CG; Wang Y; Anderson DG
J Control Release; 2012 Jun; 160(2):172-6. PubMed ID: 22155553
[TBL] [Abstract][Full Text] [Related]
11. Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles.
Sato Y; Okabe N; Note Y; Hashiba K; Maeki M; Tokeshi M; Harashima H
Acta Biomater; 2020 Jan; 102():341-350. PubMed ID: 31733331
[TBL] [Abstract][Full Text] [Related]
12. Lipid-like materials for low-dose, in vivo gene silencing.
Love KT; Mahon KP; Levins CG; Whitehead KA; Querbes W; Dorkin JR; Qin J; Cantley W; Qin LL; Racie T; Frank-Kamenetsky M; Yip KN; Alvarez R; Sah DW; de Fougerolles A; Fitzgerald K; Koteliansky V; Akinc A; Langer R; Anderson DG
Proc Natl Acad Sci U S A; 2010 Feb; 107(5):1864-9. PubMed ID: 20080679
[TBL] [Abstract][Full Text] [Related]
13. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics.
Kulkarni JA; Witzigmann D; Chen S; Cullis PR; van der Meel R
Acc Chem Res; 2019 Sep; 52(9):2435-2444. PubMed ID: 31397996
[TBL] [Abstract][Full Text] [Related]
14. Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.
Jing X; Foged C; Martin-Bertelsen B; Yaghmur A; Knapp KM; Malmsten M; Franzyk H; Nielsen HM
Mol Pharm; 2016 Jun; 13(6):1739-49. PubMed ID: 26654841
[TBL] [Abstract][Full Text] [Related]
15. Reducing the Cytotoxicity of Lipid Nanoparticles Associated with a Fusogenic Cationic Lipid in a Natural Killer Cell Line by Introducing a Polycation-Based siRNA Core.
Nakamura T; Yamada K; Fujiwara Y; Sato Y; Harashima H
Mol Pharm; 2018 Jun; 15(6):2142-2150. PubMed ID: 29668291
[TBL] [Abstract][Full Text] [Related]
16. Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo.
Jyotsana N; Sharma A; Chaturvedi A; Budida R; Scherr M; Kuchenbauer F; Lindner R; Noyan F; Sühs KW; Stangel M; Grote-Koska D; Brand K; Vornlocher HP; Eder M; Thol F; Ganser A; Humphries RK; Ramsay E; Cullis P; Heuser M
Ann Hematol; 2019 Aug; 98(8):1905-1918. PubMed ID: 31104089
[TBL] [Abstract][Full Text] [Related]
17. Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach.
Thanki K; Zeng X; Justesen S; Tejlmann S; Falkenberg E; Van Driessche E; Mørck Nielsen H; Franzyk H; Foged C
Eur J Pharm Biopharm; 2017 Nov; 120():22-33. PubMed ID: 28756280
[TBL] [Abstract][Full Text] [Related]
18. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Basha G; Novobrantseva TI; Rosin N; Tam YY; Hafez IM; Wong MK; Sugo T; Ruda VM; Qin J; Klebanov B; Ciufolini M; Akinc A; Tam YK; Hope MJ; Cullis PR
Mol Ther; 2011 Dec; 19(12):2186-200. PubMed ID: 21971424
[TBL] [Abstract][Full Text] [Related]
19. Lipid-based nanotherapeutics for siRNA delivery.
Schroeder A; Levins CG; Cortez C; Langer R; Anderson DG
J Intern Med; 2010 Jan; 267(1):9-21. PubMed ID: 20059641
[TBL] [Abstract][Full Text] [Related]
20. Development of lipidoid-siRNA formulations for systemic delivery to the liver.
Akinc A; Goldberg M; Qin J; Dorkin JR; Gamba-Vitalo C; Maier M; Jayaprakash KN; Jayaraman M; Rajeev KG; Manoharan M; Koteliansky V; Röhl I; Leshchiner ES; Langer R; Anderson DG
Mol Ther; 2009 May; 17(5):872-9. PubMed ID: 19259063
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]