BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 21750985)

  • 1. Role of polyamines in determining the cellular response to chemotherapeutic agents: modulation of protein kinase CK2 expression and activity.
    Kreutzer JN; Olsen BB; Lech K; Issinger OG; Guerra B
    Mol Cell Biochem; 2011 Oct; 356(1-2):149-58. PubMed ID: 21750985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells.
    Allen WL; McLean EG; Boyer J; McCulla A; Wilson PM; Coyle V; Longley DB; Casero RA; Johnston PG
    Mol Cancer Ther; 2007 Jan; 6(1):128-37. PubMed ID: 17237273
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
    Tummala R; Diegelman P; Hector S; Kramer DL; Clark K; Zagst P; Fetterly G; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2011 Feb; 67(2):401-14. PubMed ID: 20443003
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
    Hector S; Porter CW; Kramer DL; Clark K; Prey J; Kisiel N; Diegelman P; Chen Y; Pendyala L
    Mol Cancer Ther; 2004 Jul; 3(7):813-22. PubMed ID: 15252142
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Hector S; Tummala R; Kisiel ND; Diegelman P; Vujcic S; Clark K; Fakih M; Kramer DL; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2008 Aug; 62(3):517-27. PubMed ID: 17987291
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    Choi W; Gerner EW; Ramdas L; Dupart J; Carew J; Proctor L; Huang P; Zhang W; Hamilton SR
    J Biol Chem; 2005 Feb; 280(5):3295-304. PubMed ID: 15546879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.
    Uimari A; Keinänen TA; Karppinen A; Woster P; Uimari P; Jänne J; Alhonen L
    Biochem J; 2009 Jul; 422(1):101-9. PubMed ID: 19473115
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma.
    Tian Y; Wang S; Wang B; Zhang J; Jiang R; Zhang W
    Oncol Rep; 2012 Apr; 27(4):1227-32. PubMed ID: 22179681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation.
    Butcher NJ; Broadhurst GM; Minchin RF
    J Biol Chem; 2007 Sep; 282(39):28530-28539. PubMed ID: 17690107
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.
    Stanic' I; Facchini A; Borzì RM; Stefanelli C; Flamigni F
    J Cell Physiol; 2009 Apr; 219(1):109-16. PubMed ID: 19097065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death.
    Holst CM; Johansson VM; Alm K; Oredsson SM
    Cell Biol Int; 2008 Jan; 32(1):66-74. PubMed ID: 17920946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis.
    Shappell NW; Fogel-Petrovic MF; Porter CW
    FEBS Lett; 1993 Apr; 321(2-3):179-83. PubMed ID: 8477847
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.
    Stanic I; Cetrullo S; Facchini A; Stefanelli C; Borzì RM; Tantini B; Guarnieri C; Caldarera CM; Flamigni F
    J Cell Physiol; 2008 Jul; 216(1):153-61. PubMed ID: 18231987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
    Gurkan AC; Arisan ED; Yerlikaya PO; Ilhan H; Unsal NP
    Cell Oncol (Dordr); 2018 Jun; 41(3):297-317. PubMed ID: 29492901
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.
    Pledgie-Tracy A; Billam M; Hacker A; Sobolewski MD; Woster PM; Zhang Z; Casero RA; Davidson NE
    Cancer Chemother Pharmacol; 2010 May; 65(6):1067-81. PubMed ID: 19727732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.
    Pledgie A; Huang Y; Hacker A; Zhang Z; Woster PM; Davidson NE; Casero RA
    J Biol Chem; 2005 Dec; 280(48):39843-51. PubMed ID: 16207710
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
    Murray-Stewart T; Dunworth M; Lui Y; Giardiello FM; Woster PM; Casero RA
    PLoS One; 2018; 13(8):e0202677. PubMed ID: 30138353
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M; Vujcic S; Brown PJ; Haddox MK; Porter CW
    Biochemistry; 1996 Nov; 35(45):14436-44. PubMed ID: 8916930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity of the polyamine analog N(1), N(11)-diethylnorspermine against human prostate carcinoma cells.
    Schipper RG; Deli G; Deloyer P; Lange WP; Schalken JA; Verhofstad AA
    Prostate; 2000 Sep; 44(4):313-21. PubMed ID: 10951496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis induced by the potential chemotherapeutic drug N1, N11-Diethylnorspermine in a neuroblastoma cell line.
    Söderstjerna E; Holst CM; Alm K; Oredsson SM
    Anticancer Drugs; 2010 Nov; 21(10):917-26. PubMed ID: 20729713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.