BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1354 related articles for article (PubMed ID: 21752789)

  • 41. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.
    Tu PH; Raju P; Robinson KA; Gurney ME; Trojanowski JQ; Lee VM
    Proc Natl Acad Sci U S A; 1996 Apr; 93(7):3155-60. PubMed ID: 8610185
    [TBL] [Abstract][Full Text] [Related]  

  • 42. An autopsied case of sporadic adult-onset amyotrophic lateral sclerosis with FUS-positive basophilic inclusions.
    Matsuoka T; Fujii N; Kondo A; Iwaki A; Hokonohara T; Honda H; Sasaki K; Suzuki SO; Iwaki T
    Neuropathology; 2011 Feb; 31(1):71-6. PubMed ID: 20573033
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Identification of 2 Loci at chromosomes 9 and 14 in a multiplex family with frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Gijselinck I; Engelborghs S; Maes G; Cuijt I; Peeters K; Mattheijssens M; Joris G; Cras P; Martin JJ; De Deyn PP; Kumar-Singh S; Van Broeckhoven C; Cruts M
    Arch Neurol; 2010 May; 67(5):606-16. PubMed ID: 20457961
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions.
    Nishihira Y; Tan CF; Onodera O; Toyoshima Y; Yamada M; Morita T; Nishizawa M; Kakita A; Takahashi H
    Acta Neuropathol; 2008 Aug; 116(2):169-82. PubMed ID: 18481073
    [TBL] [Abstract][Full Text] [Related]  

  • 45. mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms.
    Scherz B; Rabl R; Flunkert S; Rohler S; Neddens J; Taub N; Temmel M; Panzenboeck U; Niederkofler V; Zimmermann R; Hutter-Paier B
    PLoS One; 2018; 13(5):e0197674. PubMed ID: 29787578
    [TBL] [Abstract][Full Text] [Related]  

  • 46. GPNMB ameliorates mutant TDP-43-induced motor neuron cell death.
    Nagahara Y; Shimazawa M; Ohuchi K; Ito J; Takahashi H; Tsuruma K; Kakita A; Hara H
    J Neurosci Res; 2017 Aug; 95(8):1647-1665. PubMed ID: 27935101
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis.
    Woolley SC; Strong MJ
    Neurol Clin; 2015 Nov; 33(4):787-805. PubMed ID: 26515622
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis.
    Swarup V; Audet JN; Phaneuf D; Kriz J; Julien JP
    J Neurosci; 2012 Dec; 32(50):18186-95. PubMed ID: 23238732
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.
    Nishimura AL; Zupunski V; Troakes C; Kathe C; Fratta P; Howell M; Gallo JM; Hortobágyi T; Shaw CE; Rogelj B
    Brain; 2010 Jun; 133(Pt 6):1763-71. PubMed ID: 20472655
    [TBL] [Abstract][Full Text] [Related]  

  • 50. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.
    Vernay A; Therreau L; Blot B; Risson V; Dirrig-Grosch S; Waegaert R; Lequeu T; Sellal F; Schaeffer L; Sadoul R; Loeffler JP; René F
    Hum Mol Genet; 2016 Aug; 25(15):3341-3360. PubMed ID: 27329763
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Distinct biochemical signatures characterize peripherin isoform expression in both traumatic neuronal injury and motor neuron disease.
    McLean J; Liu HN; Miletic D; Weng YC; Rogaeva E; Zinman L; Kriz J; Robertson J
    J Neurochem; 2010 Aug; 114(4):1177-92. PubMed ID: 20533992
    [TBL] [Abstract][Full Text] [Related]  

  • 52. [Neuropathology of frontotemporal lobar degeneration with ubiquitinated inclusions].
    Yoshida M
    Brain Nerve; 2009 Nov; 61(11):1308-18. PubMed ID: 19938688
    [TBL] [Abstract][Full Text] [Related]  

  • 53. TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.
    Suzuki H; Lee K; Matsuoka M
    J Biol Chem; 2011 Apr; 286(15):13171-83. PubMed ID: 21339291
    [TBL] [Abstract][Full Text] [Related]  

  • 54. TDP-43 and FUS: a nuclear affair.
    Dormann D; Haass C
    Trends Neurosci; 2011 Jul; 34(7):339-48. PubMed ID: 21700347
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.
    Chen HJ; Mitchell JC; Novoselov S; Miller J; Nishimura AL; Scotter EL; Vance CA; Cheetham ME; Shaw CE
    Brain; 2016 May; 139(Pt 5):1417-32. PubMed ID: 26936937
    [TBL] [Abstract][Full Text] [Related]  

  • 57. An autopsy case of frontotemporal lobar degeneration with the appearance of fused in sarcoma inclusions (basophilic inclusion body disease) clinically presenting corticobasal syndrome.
    Matsumoto A; Suzuki H; Fukatsu R; Shimizu H; Suzuki Y; Hisanaga K
    Neuropathology; 2016 Feb; 36(1):77-87. PubMed ID: 26227957
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Molecular basis of amyotrophic lateral sclerosis.
    Liscic RM; Breljak D
    Prog Neuropsychopharmacol Biol Psychiatry; 2011 Mar; 35(2):370-2. PubMed ID: 20655970
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Temporal profiles of neuronal degeneration, glial proliferation, and cell death in hNFL(+/+) and NFL(-/-) mice.
    McLean JR; Sanelli TR; Leystra-Lantz C; He BP; Strong MJ
    Glia; 2005 Oct; 52(1):59-69. PubMed ID: 15920739
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
    Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
    Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 68.