267 related articles for article (PubMed ID: 21757497)
1. Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Wang W; Nyman JS; Ono K; Stevenson DA; Yang X; Elefteriou F
Hum Mol Genet; 2011 Oct; 20(20):3910-24. PubMed ID: 21757497
[TBL] [Abstract][Full Text] [Related]
2. Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model.
Rhodes SD; Wu X; He Y; Chen S; Yang H; Staser KW; Wang J; Zhang P; Jiang C; Yokota H; Dong R; Peng X; Yang X; Murthy S; Azhar M; Mohammad KS; Xu M; Guise TA; Yang FC
J Bone Miner Res; 2013 Dec; 28(12):2476-89. PubMed ID: 23703870
[TBL] [Abstract][Full Text] [Related]
3. Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice.
Sharma R; Wu X; Rhodes SD; Chen S; He Y; Yuan J; Li J; Yang X; Li X; Jiang L; Kim ET; Stevenson DA; Viskochil D; Xu M; Yang FC
Hum Mol Genet; 2013 Dec; 22(23):4818-28. PubMed ID: 23863460
[TBL] [Abstract][Full Text] [Related]
4. Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
de la Croix Ndong J; Makowski AJ; Uppuganti S; Vignaux G; Ono K; Perrien DS; Joubert S; Baglio SR; Granchi D; Stevenson DA; Rios JJ; Nyman JS; Elefteriou F
Nat Med; 2014 Aug; 20(8):904-10. PubMed ID: 24997609
[TBL] [Abstract][Full Text] [Related]
5. Ras dependent paracrine secretion of osteopontin by Nf1+/- osteoblasts promote osteoclast activation in a neurofibromatosis type I murine model.
Li H; Liu Y; Zhang Q; Jing Y; Chen S; Song Z; Yan J; Li Y; Wu X; Zhang X; Zhang Y; Case J; Yu M; Ingram DA; Yang FC
Pediatr Res; 2009 Jun; 65(6):613-8. PubMed ID: 19247213
[TBL] [Abstract][Full Text] [Related]
6. Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.
Kühnisch J; Seto J; Lange C; Schrof S; Stumpp S; Kobus K; Grohmann J; Kossler N; Varga P; Osswald M; Emmerich D; Tinschert S; Thielemann F; Duda G; Seifert W; El Khassawna T; Stevenson DA; Elefteriou F; Kornak U; Raum K; Fratzl P; Mundlos S; Kolanczyk M
PLoS One; 2014; 9(1):e86115. PubMed ID: 24465906
[TBL] [Abstract][Full Text] [Related]
7. Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice.
de la Croix Ndong J; Stevens DM; Vignaux G; Uppuganti S; Perrien DS; Yang X; Nyman JS; Harth E; Elefteriou F
J Bone Miner Res; 2015 Jan; 30(1):55-63. PubMed ID: 25043591
[TBL] [Abstract][Full Text] [Related]
8. NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos.
Kuorilehto T; Nissinen M; Koivunen J; Benson MD; Peltonen J
J Bone Miner Res; 2004 Jun; 19(6):983-9. PubMed ID: 15125795
[TBL] [Abstract][Full Text] [Related]
9. A murine model of neurofibromatosis type 1 tibial pseudarthrosis featuring proliferative fibrous tissue and osteoclast-like cells.
El-Hoss J; Sullivan K; Cheng T; Yu NY; Bobyn JD; Peacock L; Mikulec K; Baldock P; Alexander IE; Schindeler A; Little DG
J Bone Miner Res; 2012 Jan; 27(1):68-78. PubMed ID: 21956219
[TBL] [Abstract][Full Text] [Related]
10. MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.
Bok S; Shin DY; Yallowitz AR; Eiseman M; Cung M; Xu R; Li N; Sun J; Williams AL; Scott JE; Su B; Shim JH; Greenblatt MB
Nat Commun; 2020 Nov; 11(1):5704. PubMed ID: 33177525
[TBL] [Abstract][Full Text] [Related]
11. Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Wang W; Nyman JS; Moss HE; Gutierrez G; Mundy GR; Yang X; Elefteriou F
J Bone Miner Res; 2010 Jul; 25(7):1658-67. PubMed ID: 20200958
[TBL] [Abstract][Full Text] [Related]
12. Multiple roles for neurofibromin in skeletal development and growth.
Kolanczyk M; Kossler N; Kühnisch J; Lavitas L; Stricker S; Wilkening U; Manjubala I; Fratzl P; Spörle R; Herrmann BG; Parada LF; Kornak U; Mundlos S
Hum Mol Genet; 2007 Apr; 16(8):874-86. PubMed ID: 17317783
[TBL] [Abstract][Full Text] [Related]
13. JNK inhibitors increase osteogenesis in Nf1-deficient cells.
Sullivan K; El-Hoss J; Little DG; Schindeler A
Bone; 2011 Dec; 49(6):1311-6. PubMed ID: 21964323
[TBL] [Abstract][Full Text] [Related]
14. Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background.
Alanne MH; Siljamäki E; Peltonen S; Väänänen K; Windle JJ; Parada LF; Määttä JA; Peltonen J
J Cell Biochem; 2012 Jun; 113(6):2136-46. PubMed ID: 22307743
[TBL] [Abstract][Full Text] [Related]
15. The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Ono K; Karolak MR; Ndong Jde L; Wang W; Yang X; Elefteriou F
Hum Mol Genet; 2013 Aug; 22(15):3048-62. PubMed ID: 23571107
[TBL] [Abstract][Full Text] [Related]
16. Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.
Kamiya N; Yamaguchi R; Aruwajoye O; Kim AJ; Kuroyanagi G; Phipps M; Adapala NS; Feng JQ; Kim HK
J Bone Miner Res; 2017 Aug; 32(8):1716-1726. PubMed ID: 28425622
[TBL] [Abstract][Full Text] [Related]
17. A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.
Zhang T; Jia C; Dong Z; Li C; Lu W
Mol Genet Genomic Med; 2021 May; 9(5):e1643. PubMed ID: 33764694
[TBL] [Abstract][Full Text] [Related]
18. Neurofibromin (Nf1) is required for skeletal muscle development.
Kossler N; Stricker S; Rödelsperger C; Robinson PN; Kim J; Dietrich C; Osswald M; Kühnisch J; Stevenson DA; Braun T; Mundlos S; Kolanczyk M
Hum Mol Genet; 2011 Jul; 20(14):2697-709. PubMed ID: 21478499
[TBL] [Abstract][Full Text] [Related]
19. Is osseous dysplasia a primary feature of neurofibromatosis 1 (NF1)?
Alwan S; Tredwell SJ; Friedman JM
Clin Genet; 2005 May; 67(5):378-90. PubMed ID: 15811002
[TBL] [Abstract][Full Text] [Related]
20. Recent insights into bone development, homeostasis, and repair in type 1 neurofibromatosis (NF1).
Schindeler A; Little DG
Bone; 2008 Apr; 42(4):616-22. PubMed ID: 18248783
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
