BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

63 related articles for article (PubMed ID: 21762707)

  • 1. The repair of melphalan-induced DNA adducts in the transcribed strand of active genes is subject to a strong polarity effect.
    Episkopou H; Kyrtopoulos SA; Sfikakis PP; Dimopoulos MA; Souliotis VL
    Mutat Res; 2011 Sep; 714(1-2):78-87. PubMed ID: 21762707
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preferential in vivo DNA repair of melphalan-induced damage in human genes is greatly affected by the local chromatin structure.
    Souliotis VL; Dimopoulos MA; Episkopou HG; Kyrtopoulos SA; Sfikakis PP
    DNA Repair (Amst); 2006 Aug; 5(8):972-85. PubMed ID: 16781199
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts.
    Episkopou H; Kyrtopoulos SA; Sfikakis PP; Fousteri M; Dimopoulos MA; Mullenders LH; Souliotis VL
    Cancer Res; 2009 May; 69(10):4424-33. PubMed ID: 19417135
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Extent of damage and repair in the p53 tumor-suppressor gene after treatment of myeloma patients with high-dose melphalan and autologous blood stem-cell transplantation is individualized and may predict clinical outcome.
    Dimopoulos MA; Souliotis VL; Anagnostopoulos A; Papadimitriou C; Sfikakis PP
    J Clin Oncol; 2005 Jul; 23(19):4381-9. PubMed ID: 15883412
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gene-specific formation and repair of DNA monoadducts and interstrand cross-links after therapeutic exposure to nitrogen mustards.
    Souliotis VL; Dimopoulos MA; Sfikakis PP
    Clin Cancer Res; 2003 Oct; 9(12):4465-74. PubMed ID: 14555520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA; Zhu Q; El-Mahdy M; Venkatachalam S; Wani AA
    Cancer Res; 2000 Apr; 60(8):2273-80. PubMed ID: 10786695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide.
    Snyderwine EG; Bohr VA
    Cancer Res; 1992 Aug; 52(15):4183-9. PubMed ID: 1638532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
    Denissenko MF; Pao A; Pfeifer GP; Tang M
    Oncogene; 1998 Mar; 16(10):1241-7. PubMed ID: 9546425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA strand bias in the repair of the p53 gene in normal human and xeroderma pigmentosum group C fibroblasts.
    Evans MK; Taffe BG; Harris CC; Bohr VA
    Cancer Res; 1993 Nov; 53(22):5377-81. PubMed ID: 8221675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of transcriptional activity of p53 by ultraviolet radiation: linkage between p53 pathway and DNA repair through damage recognition.
    Zhu Q; Wani MA; El-Mahdy M; Wani G; Wani AA
    Mol Carcinog; 2000 Aug; 28(4):215-24. PubMed ID: 10972991
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes.
    Dumaz N; Duthu A; Ehrhart JC; Drougard C; Appella E; Anderson CW; May P; Sarasin A; Daya-Grosjean L
    Mol Carcinog; 1997 Dec; 20(4):340-7. PubMed ID: 9433478
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In UV-irradiated Saccharomyces cerevisiae, overexpression of Swi2/Snf2 family member Rad26 increases transcription-coupled repair and repair of the non-transcribed strand.
    Bucheli M; Sweder K
    Mol Microbiol; 2004 Jun; 52(6):1653-63. PubMed ID: 15186415
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Excision repair at the level of the nucleotide in the Saccharomyces cerevisiae MFA2 gene: mapping of where enhanced repair in the transcribed strand begins or ends and identification of only a partial rad16 requisite for repairing upstream control sequences.
    Teng Y; Li S; Waters R; Reed SH
    J Mol Biol; 1997 Mar; 267(2):324-37. PubMed ID: 9096229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preferential DNA damage in the p53 gene by benzo[a]pyrene metabolites in cytochrome P4501A1-expressing xeroderma pigmentosum group A cells.
    Quan T; States JC
    Mol Carcinog; 1996 May; 16(1):32-43. PubMed ID: 8634092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. U.v.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle.
    Yamaizumi M; Sugano T
    Oncogene; 1994 Oct; 9(10):2775-84. PubMed ID: 8084582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment.
    Bulmer JT; Zacal NJ; Rainbow AJ
    Cancer Chemother Pharmacol; 2005 Aug; 56(2):189-98. PubMed ID: 15841377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene.
    Wellinger RE; Thoma F
    EMBO J; 1997 Aug; 16(16):5046-56. PubMed ID: 9305646
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA repair fine structure in Werner's syndrome cell lines.
    Webb DK; Evans MK; Bohr VA
    Exp Cell Res; 1996 May; 224(2):272-8. PubMed ID: 8612704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chromatin structure modulates DNA repair by photolyase in vivo.
    Suter B; Livingstone-Zatchej M; Thoma F
    EMBO J; 1997 Apr; 16(8):2150-60. PubMed ID: 9155040
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of strand-specific repair of UV-induced DNA lesions in three genes of the archaeon Sulfolobus solfataricus.
    Romano V; Napoli A; Salerno V; Valenti A; Rossi M; Ciaramella M
    J Mol Biol; 2007 Jan; 365(4):921-9. PubMed ID: 17113105
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.