BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 21763149)

  • 1. Structural modifications of quinolone-3-carboxylic acids with anti-HIV activity.
    He QQ; Gu SX; Liu J; Wu HQ; Zhang X; Yang LM; Zheng YT; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(16):5039-45. PubMed ID: 21763149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of HQCAs with aryl or benzyl substituents on N-1 position as potential HIV-1 integrase inhibitors.
    He QQ; Zhang X; Wu HQ; Gu SX; Ma XD; Yang LM; Zheng YT; Chen FE
    Bioorg Med Chem; 2011 Sep; 19(18):5553-8. PubMed ID: 21862337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors.
    He QQ; Zhang X; Yang LM; Zheng YT; Chen F
    J Enzyme Inhib Med Chem; 2013 Aug; 28(4):671-6. PubMed ID: 22468749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives.
    Santos Fda C; Abreu P; Castro HC; Paixão IC; Cirne-Santos CC; Giongo V; Barbosa JE; Simonetti BR; Garrido V; Bou-Habib DC; Silva Dde O; Batalha PN; Temerozo JR; Souza TM; Nogueira CM; Cunha AC; Rodrigues CR; Ferreira VF; de Souza MC
    Bioorg Med Chem; 2009 Aug; 17(15):5476-81. PubMed ID: 19581097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural modifications of DAPY analogues with potent anti-HIV-1 activity.
    Feng XQ; Liang YH; Zeng ZS; Chen FE; Balzarini J; Pannecouque C; De Clercq E
    ChemMedChem; 2009 Feb; 4(2):219-24. PubMed ID: 19090525
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ma XD; Zhang X; Yang SQ; Dai HF; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(16):4704-9. PubMed ID: 21788138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
    Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
    Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach.
    Zhan P; Chen W; Li Z; Li X; Chen X; Tian Y; Pannecouque C; Clercq ED; Liu X
    Bioorg Med Chem; 2012 Dec; 20(23):6795-802. PubMed ID: 23098609
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives.
    Tabarrini O; Massari S; Daelemans D; Meschini F; Manfroni G; Bottega L; Gatto B; Palumbo M; Pannecouque C; Cecchetti V
    ChemMedChem; 2010 Nov; 5(11):1880-92. PubMed ID: 20928882
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
    Hopkins AL; Ren J; Milton J; Hazen RJ; Chan JH; Stuart DI; Stammers DK
    J Med Chem; 2004 Nov; 47(24):5912-22. PubMed ID: 15537346
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV.
    Feng XQ; Zeng ZS; Liang YH; Chen FE; Pannecouque C; Balzarini J; De Clercq E
    Bioorg Med Chem; 2010 Apr; 18(7):2370-4. PubMed ID: 20307984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity.
    Tabarrini O; Massari S; Sancineto L; Daelemans D; Sabatini S; Manfroni G; Cecchetti V; Pannecouque C
    ChemMedChem; 2011 Jul; 6(7):1249-57. PubMed ID: 21567967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Zhan P; Liu X; Fang Z; Li Z; Pannecouque C; De Clercq E
    Eur J Med Chem; 2009 Nov; 44(11):4648-53. PubMed ID: 19628308
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationship of 7-(substituted)-aminomethyl-4-quinolone-3-carboxylic acid derivatives.
    Zhang Z; Yu A; Zhou W
    Bioorg Med Chem; 2007 Dec; 15(23):7274-80. PubMed ID: 17826097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors.
    Zhan P; Liu XY; Li ZY; Fang ZJ; Pannecouque C; De Clercq E
    Chem Biodivers; 2010 Jul; 7(7):1717-27. PubMed ID: 20658659
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase--discovery of a new polyhydroxylated antiviral agent.
    Maurin C; Lion C; Bailly F; Touati N; Vezin H; Mbemba G; Mouscadet JF; Debyser Z; Witvrouw M; Cotelle P
    Bioorg Med Chem; 2010 Jul; 18(14):5194-201. PubMed ID: 20541944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase.
    Wang Z; Vince R
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1293-6. PubMed ID: 18226894
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents.
    He YP; Long J; Zhang SS; Li C; Lai CC; Zhang CS; Li DX; Zhang DH; Wang H; Cai QQ; Zheng YT
    Bioorg Med Chem Lett; 2011 Jan; 21(2):694-7. PubMed ID: 21194939
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitro.
    Cheng P; Huang N; Jiang ZY; Zhang Q; Zheng YT; Chen JJ; Zhang XM; Ma YB
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2475-8. PubMed ID: 18316190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-HIV diarylpyrimidine-quinolone hybrids and their mode of action.
    Mao TQ; He QQ; Wan ZY; Chen WX; Chen FE; Tang GF; De Clercq E; Daelemans D; Pannecouque C
    Bioorg Med Chem; 2015 Jul; 23(13):3860-8. PubMed ID: 25907370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.