212 related articles for article (PubMed ID: 21763680)
1. Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer.
Lu CW; Lin SC; Chien CW; Lin SC; Lee CT; Lin BW; Lee JC; Tsai SJ
Am J Pathol; 2011 Sep; 179(3):1405-14. PubMed ID: 21763680
[TBL] [Abstract][Full Text] [Related]
2. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance.
Lu CW; Lin SC; Chen KF; Lai YY; Tsai SJ
J Biol Chem; 2008 Oct; 283(42):28106-14. PubMed ID: 18718909
[TBL] [Abstract][Full Text] [Related]
3. HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.
Prigione A; Rohwer N; Hoffmann S; Mlody B; Drews K; Bukowiecki R; Blümlein K; Wanker EE; Ralser M; Cramer T; Adjaye J
Stem Cells; 2014 Feb; 32(2):364-76. PubMed ID: 24123565
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.
Kluza J; Corazao-Rozas P; Touil Y; Jendoubi M; Maire C; Guerreschi P; Jonneaux A; Ballot C; Balayssac S; Valable S; Corroyer-Dulmont A; Bernaudin M; Malet-Martino M; de Lassalle EM; Maboudou P; Formstecher P; Polakowska R; Mortier L; Marchetti P
Cancer Res; 2012 Oct; 72(19):5035-47. PubMed ID: 22865452
[TBL] [Abstract][Full Text] [Related]
5. Diversity of the pyruvate dehydrogenase kinase gene family in humans.
Gudi R; Bowker-Kinley MM; Kedishvili NY; Zhao Y; Popov KM
J Biol Chem; 1995 Dec; 270(48):28989-94. PubMed ID: 7499431
[TBL] [Abstract][Full Text] [Related]
6. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia.
Peng F; Wang JH; Fan WJ; Meng YT; Li MM; Li TT; Cui B; Wang HF; Zhao Y; An F; Guo T; Liu XF; Zhang L; Lv L; Lv DK; Xu LZ; Xie JJ; Lin WX; Lam EW; Xu J; Liu Q
Oncogene; 2018 Feb; 37(8):1062-1074. PubMed ID: 29106390
[TBL] [Abstract][Full Text] [Related]
7. Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic
Cenigaonandia-Campillo A; Serna-Blasco R; Gómez-Ocabo L; Solanes-Casado S; Baños-Herraiz N; Puerto-Nevado LD; Cañas JA; Aceñero MJ; García-Foncillas J; Aguilera Ó
Theranostics; 2021; 11(8):3595-3606. PubMed ID: 33664850
[No Abstract] [Full Text] [Related]
8. Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function.
Halvarsson C; Eliasson P; Jönsson JI
PLoS One; 2017; 12(2):e0171714. PubMed ID: 28182733
[TBL] [Abstract][Full Text] [Related]
9. Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance.
Xu J; Shi Q; Xu W; Zhou Q; Shi R; Ma Y; Chen D; Zhu L; Feng L; Cheng AS; Morrison H; Wang X; Jin H
Theranostics; 2019; 9(10):2999-3013. PubMed ID: 31244938
[No Abstract] [Full Text] [Related]
10. Structural determinants for cross-talk between pyruvate dehydrogenase kinase 3 and lipoyl domain 2 of the human pyruvate dehydrogenase complex.
Tso SC; Kato M; Chuang JL; Chuang DT
J Biol Chem; 2006 Sep; 281(37):27197-204. PubMed ID: 16849321
[TBL] [Abstract][Full Text] [Related]
11. Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer.
Yoon S; Kim JG; Seo AN; Park SY; Kim HJ; Park JS; Choi GS; Jeong JY; Jun do Y; Yoon GS; Kang BW
Oncology; 2015; 89(6):351-9. PubMed ID: 26439504
[TBL] [Abstract][Full Text] [Related]
12. Serum pyruvate dehydrogenase kinase as a prognostic marker for cholangiocarcinoma.
Sanmai S; Proungvitaya T; Limpaiboon T; Chua-On D; Seubwai W; Roytrakul S; Wongkham S; Wongkham C; Somintara O; Sangkhamanon S; Proungvitaya S
Oncol Lett; 2019 Jun; 17(6):5275-5282. PubMed ID: 31186744
[TBL] [Abstract][Full Text] [Related]
13. Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.
Hur H; Xuan Y; Kim YB; Lee G; Shim W; Yun J; Ham IH; Han SU
Int J Oncol; 2013 Jan; 42(1):44-54. PubMed ID: 23135628
[TBL] [Abstract][Full Text] [Related]
14. Excess glucose induces hypoxia-inducible factor-1α in pancreatic cancer cells and stimulates glucose metabolism and cell migration.
Liu Z; Jia X; Duan Y; Xiao H; Sundqvist KG; Permert J; Wang F
Cancer Biol Ther; 2013 May; 14(5):428-35. PubMed ID: 23377827
[TBL] [Abstract][Full Text] [Related]
15. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway.
Wang H; Zhao L; Zhu LT; Wang Y; Pan D; Yao J; You QD; Guo QL
Mol Carcinog; 2014 Feb; 53 Suppl 1():E107-18. PubMed ID: 23761018
[TBL] [Abstract][Full Text] [Related]
16. Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.
Goodwin J; Choi H; Hsieh MH; Neugent ML; Ahn JM; Hayenga HN; Singh PK; Shackelford DB; Lee IK; Shulaev V; Dhar S; Takeda N; Kim JW
Am J Respir Cell Mol Biol; 2018 Feb; 58(2):216-231. PubMed ID: 28915065
[TBL] [Abstract][Full Text] [Related]
17. Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer.
Nunes-Xavier CE; Mingo J; Emaldi M; Flem-Karlsen K; Mælandsmo GM; Fodstad Ø; Llarena R; López JI; Pulido R
Front Oncol; 2022; 12():873516. PubMed ID: 35692804
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma.
Kuo YH; Chan TC; Lai HY; Chen TJ; Wu LC; Hsing CH; Li CF
Front Oncol; 2021; 11():749142. PubMed ID: 34589439
[TBL] [Abstract][Full Text] [Related]
19. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Kim JW; Tchernyshyov I; Semenza GL; Dang CV
Cell Metab; 2006 Mar; 3(3):177-85. PubMed ID: 16517405
[TBL] [Abstract][Full Text] [Related]
20. Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.
Ognibene M; Cangelosi D; Morini M; Segalerba D; Bosco MC; Sementa AR; Eva A; Varesio L
PLoS One; 2017; 12(11):e0187206. PubMed ID: 29117193
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]