BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

866 related articles for article (PubMed ID: 21765015)

  • 1. Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis.
    Roda JM; Sumner LA; Evans R; Phillips GS; Marsh CB; Eubank TD
    J Immunol; 2011 Aug; 187(4):1970-6. PubMed ID: 21765015
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
    Roda JM; Wang Y; Sumner LA; Phillips GS; Marsh CB; Eubank TD
    J Immunol; 2012 Sep; 189(6):3168-77. PubMed ID: 22869907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes.
    Eubank TD; Roda JM; Liu H; O'Neil T; Marsh CB
    Blood; 2011 Jan; 117(1):323-32. PubMed ID: 20952691
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia inducible factors-mediated inhibition of cancer by GM-CSF: a mathematical model.
    Chen D; Roda JM; Marsh CB; Eubank TD; Friedman A
    Bull Math Biol; 2012 Nov; 74(11):2752-77. PubMed ID: 23073704
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer.
    Steinberger KJ; Forget MA; Bobko AA; Mihalik NE; Gencheva M; Roda JM; Cole SL; Mo X; Hoblitzell EH; Evans R; Gross AC; Moldovan L; Marsh CB; Khramstov VV; Eubank TD
    J Immunol; 2020 Oct; 205(8):2301-2311. PubMed ID: 32938724
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Melanoma exosome induction of endothelial cell GM-CSF in pre-metastatic lymph nodes may result in different M1 and M2 macrophage mediated angiogenic processes.
    Hood JL
    Med Hypotheses; 2016 Sep; 94():118-22. PubMed ID: 27515216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
    Puppo M; Battaglia F; Ottaviano C; Delfino S; Ribatti D; Varesio L; Bosco MC
    Mol Cancer Ther; 2008 Jul; 7(7):1974-84. PubMed ID: 18645007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
    Spinella F; Rosanò L; Del Duca M; Di Castro V; Nicotra MR; Natali PG; Bagnato A
    PLoS One; 2010 Jun; 5(6):e11241. PubMed ID: 20574527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.
    Chae KS; Kang MJ; Lee JH; Ryu BK; Lee MG; Her NG; Ha TK; Han J; Kim YK; Chi SG
    Oncogene; 2011 Mar; 30(10):1213-28. PubMed ID: 21057546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF.
    Knowles HJ; Athanasou NA
    J Pathol; 2008 May; 215(1):56-66. PubMed ID: 18283716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1.
    Yamashita T; Ohneda K; Nagano M; Miyoshi C; Kaneko N; Miwa Y; Yamamoto M; Ohneda O; Fujii-Kuriyama Y
    J Biol Chem; 2008 Jul; 283(27):18926-36. PubMed ID: 18434321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hypoxia inducible factor 1α and hypoxia inducible factor 2α play distinct and functionally overlapping roles in oral squamous cell carcinoma.
    Zhu GQ; Tang YL; Li L; Zheng M; Jiang J; Li XY; Chen SX; Liang XH
    Clin Cancer Res; 2010 Oct; 16(19):4732-41. PubMed ID: 20807755
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia inducible factor-1α/vascular endothelial growth factor signaling activation correlates with response to radiotherapy and its inhibition reduces hypoxia-induced angiogenesis in lung cancer.
    Zhu H; Zhang S
    J Cell Biochem; 2018 Sep; 119(9):7707-7718. PubMed ID: 29904944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
    Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Paracrine regulation of vascular endothelial growth factor--a expression during macrophage-melanoma cell interaction: role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor.
    Varney ML; Olsen KJ; Mosley RL; Singh RK
    J Interferon Cytokine Res; 2005 Nov; 25(11):674-83. PubMed ID: 16318581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lenticular cytoprotection. Part 1: the role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia.
    Neelam S; Brooks MM; Cammarata PR
    Mol Vis; 2013; 19():1-15. PubMed ID: 23335846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascularization.
    Noguera R; Fredlund E; Piqueras M; Pietras A; Beckman S; Navarro S; Påhlman S
    Clin Cancer Res; 2009 Dec; 15(23):7130-6. PubMed ID: 19903792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma.
    Sivridis E; Giatromanolaki A; Gatter KC; Harris AL; Koukourakis MI;
    Cancer; 2002 Sep; 95(5):1055-63. PubMed ID: 12209691
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis.
    Paradziej-Łukowicz J; Skwarska A; Peszyńska-Sularz G; Brillowska-Dąbrowska A; Konopa J
    Cancer Biol Ther; 2011 Oct; 12(7):586-97. PubMed ID: 21775820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.